Class information for:
Level 1: CFTR//CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR//GREGORY FLEMING JAMES CYST FIBROSIS

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
1039 2799 45.0 88%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
660 12667 CYSTIC FIBROSIS//CFTR//JOURNAL OF CYSTIC FIBROSIS

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CFTR Author keyword 179 35% 15% 419
2 CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Author keyword 159 44% 10% 273
3 GREGORY FLEMING JAMES CYST FIBROSIS Address 82 58% 3% 94
4 DELTA F508 CFTR Author keyword 35 89% 1% 16
5 AIRWAY SURFACE LIQUID Author keyword 27 48% 1% 41
6 F508DEL CFTR Author keyword 23 86% 0% 12
7 CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR Author keyword 23 43% 1% 41
8 CFTR CHLORIDE CHANNEL Author keyword 21 85% 0% 11
9 CHLORIDE CHANNEL Author keyword 20 15% 4% 124
10 CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE Author keyword 20 51% 1% 28

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 CFTR 179 35% 15% 419 Search CFTR Search CFTR
2 CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR 159 44% 10% 273 Search CYSTIC+FIBROSIS+TRANSMEMBRANE+CONDUCTANCE+REGULATOR Search CYSTIC+FIBROSIS+TRANSMEMBRANE+CONDUCTANCE+REGULATOR
3 DELTA F508 CFTR 35 89% 1% 16 Search DELTA+F508+CFTR Search DELTA+F508+CFTR
4 AIRWAY SURFACE LIQUID 27 48% 1% 41 Search AIRWAY+SURFACE+LIQUID Search AIRWAY+SURFACE+LIQUID
5 F508DEL CFTR 23 86% 0% 12 Search F508DEL+CFTR Search F508DEL+CFTR
6 CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR 23 43% 1% 41 Search CYSTIC+FIBROSIS+TRANSMEMBRANE+CONDUCTANCE+REGULATOR+CFTR Search CYSTIC+FIBROSIS+TRANSMEMBRANE+CONDUCTANCE+REGULATOR+CFTR
7 CFTR CHLORIDE CHANNEL 21 85% 0% 11 Search CFTR+CHLORIDE+CHANNEL Search CFTR+CHLORIDE+CHANNEL
8 CHLORIDE CHANNEL 20 15% 4% 124 Search CHLORIDE+CHANNEL Search CHLORIDE+CHANNEL
9 CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE 20 51% 1% 28 Search CYSTIC+FIBROSIS+TRANSMEMBRANE+CONDUCTANCE Search CYSTIC+FIBROSIS+TRANSMEMBRANE+CONDUCTANCE
10 IVACAFTOR 17 59% 1% 19 Search IVACAFTOR Search IVACAFTOR

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 TRANSMEMBRANE CONDUCTANCE REGULATOR 386 28% 43% 1191
2 CFTR 316 41% 21% 598
3 CFTR CHLORIDE CHANNEL 213 77% 5% 147
4 DELTA F508 CFTR 208 74% 6% 154
5 SMALL MOLECULE CORRECTORS 195 91% 3% 81
6 R DOMAIN 176 71% 5% 141
7 CL CHANNEL 130 49% 7% 193
8 CHLORIDE CHANNEL 117 24% 15% 421
9 CYSTIC FIBROSIS GENE 57 19% 10% 272
10 ANION SELECTIVITY 56 57% 2% 66

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Origins of Cystic Fibrosis Lung Disease 2015 8 69 59%
New pharmacological approaches for cystic fibrosis: Promises, progress, pitfalls 2015 10 150 33%
CFTR function and prospects for therapy 2008 234 172 70%
CFTR: folding, misfolding and correcting the Delta F508 conformational defect 2012 77 95 87%
The ABC protein turned chloride channel whose failure causes cystic fibrosis 2006 279 82 71%
Understanding how cystic fibrosis mutations disrupt CFTR function: From single molecules to animal models 2014 12 108 87%
Mechanisms of disease: Cystic fibrosis 2005 542 57 37%
New concepts of the pathogenesis of cystic fibrosis lung disease 2004 320 95 56%
Novel pharmacological strategies to treat cystic fibrosis 2013 26 53 75%
MOLECULAR MECHANISMS OF CFTR CHLORIDE CHANNEL DYSFUNCTION IN CYSTIC-FIBROSIS 1993 855 21 67%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 GREGORY FLEMING JAMES CYST FIBROSIS 82 58% 3.4% 94
2 PROGRAMME MOL STRUCT FUNCT 17 68% 0.5% 15
3 SC JOHNSON MED 17 47% 0.9% 26
4 CYST FIBROSIS 15 13% 3.8% 107
5 CYST FIBROSIS PULM TREATMENT 14 18% 2.4% 67
6 CYST FIBROSIS TREATMENT 13 50% 0.7% 19
7 CARDIAC MEMBRANE PHYSIOL 12 50% 0.6% 18
8 PHYSIOL BIOL CELLULAI 9 21% 1.3% 37
9 CYST FIBROSIS TRANSLAT 8 100% 0.2% 5
10 PEDIAT 0831 6 80% 0.1% 4

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000251804 HUMAN MOL GENET PROGRAM//BAK FOONG PILL//EPITHELIAL CELL BIOL
2 0.0000236105 TRANSEPITHELIAL ELECTRICAL POTENTIAL DIFFERENCE//PATHOBIOCHEM CLIN CHEM//SWEAT GLAND
3 0.0000169917 GENE MED GRP//GENEMED GRP//EXPT TREATMENT CYST FIBROSIS
4 0.0000159127 ISOLATED PANCREATIC DUCT//PANCREATIC DUCT CELLS//PANCREATIC DUCT EPITHELIAL CELLS
5 0.0000137883 CYSTIC FIBROSIS//CFTR GENE//CBAVD
6 0.0000116541 TMEM16A//CALCIUM ACTIVATED CHLORIDE CHANNELS//CALCIUM ACTIVATED CHLORIDE CHANNEL
7 0.0000095899 RAT DISTAL COLON//CL SECRETION//CHLORIDE SECRETION
8 0.0000084663 CHLORIDE CURRENT//CALCIUM ACTIVATED CURRENT//CFTR INHIBITOR
9 0.0000078779 JOURNAL OF CYSTIC FIBROSIS//INHALED TOBRAMYCIN//PULMONARY EXACERBATION
10 0.0000072735 RHDNASE//DORNASE ALFA//MUCUS VISCOELASTICITY