Class information for: |
Basic class information |
| ID | Publications | Average number of references |
Avg. shr. active ref. in WoS |
|---|---|---|---|
| 10450 | 996 | 31.4 | 67% |
Classes in level above (level 2) |
| ID, lev. above |
Publications | Label for level above |
|---|---|---|
| 1852 | 5569 | LESCH NYHAN SYNDROME//TIAZOFURIN//LESCH NYHAN DISEASE |
Terms with highest relevance score |
| Rank | Term | Type of term | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
|---|---|---|---|---|---|---|
| 1 | TIAZOFURIN | Author keyword | 83 | 76% | 6% | 59 |
| 2 | BENZAMIDE RIBOSIDE | Author keyword | 41 | 87% | 2% | 20 |
| 3 | IMPDH | Author keyword | 22 | 45% | 4% | 37 |
| 4 | IMP DEHYDROGENASE | Author keyword | 17 | 48% | 3% | 26 |
| 5 | DENDROSTELLERA LESSERTII | Author keyword | 12 | 86% | 1% | 6 |
| 6 | INOSINE MONOPHOSPHATE DEHYDROGENASE | Author keyword | 11 | 36% | 3% | 25 |
| 7 | IMPDH INHIBITORS | Author keyword | 10 | 73% | 1% | 8 |
| 8 | IMP DEHYDROGENASE INHIBITOR | Author keyword | 9 | 83% | 1% | 5 |
| 9 | IMPDH INHIBITOR | Author keyword | 8 | 70% | 1% | 7 |
| 10 | TIAZOFURIN ANALOGUES | Author keyword | 8 | 100% | 1% | 5 |
Web of Science journal categories |
Author Key Words |
| Rank | Web of Science journal category | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
LCSH search | Wikipedia search |
|---|---|---|---|---|---|---|---|
| 1 | TIAZOFURIN | 83 | 76% | 6% | 59 | Search TIAZOFURIN | Search TIAZOFURIN |
| 2 | BENZAMIDE RIBOSIDE | 41 | 87% | 2% | 20 | Search BENZAMIDE+RIBOSIDE | Search BENZAMIDE+RIBOSIDE |
| 3 | IMPDH | 22 | 45% | 4% | 37 | Search IMPDH | Search IMPDH |
| 4 | IMP DEHYDROGENASE | 17 | 48% | 3% | 26 | Search IMP+DEHYDROGENASE | Search IMP+DEHYDROGENASE |
| 5 | DENDROSTELLERA LESSERTII | 12 | 86% | 1% | 6 | Search DENDROSTELLERA+LESSERTII | Search DENDROSTELLERA+LESSERTII |
| 6 | INOSINE MONOPHOSPHATE DEHYDROGENASE | 11 | 36% | 3% | 25 | Search INOSINE+MONOPHOSPHATE+DEHYDROGENASE | Search INOSINE+MONOPHOSPHATE+DEHYDROGENASE |
| 7 | IMPDH INHIBITORS | 10 | 73% | 1% | 8 | Search IMPDH+INHIBITORS | Search IMPDH+INHIBITORS |
| 8 | IMP DEHYDROGENASE INHIBITOR | 9 | 83% | 1% | 5 | Search IMP+DEHYDROGENASE+INHIBITOR | Search IMP+DEHYDROGENASE+INHIBITOR |
| 9 | IMPDH INHIBITOR | 8 | 70% | 1% | 7 | Search IMPDH+INHIBITOR | Search IMPDH+INHIBITOR |
| 10 | TIAZOFURIN ANALOGUES | 8 | 100% | 1% | 5 | Search TIAZOFURIN+ANALOGUES | Search TIAZOFURIN+ANALOGUES |
Key Words Plus |
| Rank | Web of Science journal category | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
|---|---|---|---|---|---|
| 1 | IMP DEHYDROGENASE | 152 | 56% | 19% | 187 |
| 2 | 5 MONOPHOSPHATE DEHYDROGENASE | 143 | 83% | 8% | 80 |
| 3 | MONOPHOSPHATE DEHYDROGENASE | 137 | 88% | 7% | 65 |
| 4 | INOSINE 5 MONOPHOSPHATE DEHYDROGENASE | 123 | 70% | 10% | 103 |
| 5 | 2 BETA D RIBOFURANOSYLTHIAZOLE 4 CARBOXAMIDE | 100 | 84% | 5% | 54 |
| 6 | TIAZOFURIN | 99 | 58% | 12% | 115 |
| 7 | INOSINE 5 PHOSPHATE DEHYDROGENASE | 87 | 94% | 3% | 31 |
| 8 | HUMAN IMP DEHYDROGENASE | 81 | 80% | 5% | 51 |
| 9 | HUMAN NORMAL LYMPHOCYTES | 74 | 79% | 5% | 48 |
| 10 | INOSINE MONOPHOSPHATE DEHYDROGENASE | 55 | 43% | 10% | 97 |
Journals |
Reviews |
| Title | Publ. year | Cit. | Active references | % act. ref. to same field |
|---|---|---|---|---|
| IMP Dehydrogenase: Structure, Mechanism, and Inhibition | 2009 | 80 | 229 | 71% |
| Recent development of IMP dehydrogenase inhibitors for the treatment of cancer | 2007 | 54 | 82 | 88% |
| The Antibiotic Potential of Prokaryotic IMP Dehydrogenase Inhibitors | 2011 | 17 | 71 | 49% |
| The structure of inosine 5 '-monophosphate dehydrogenase and the design of novel inhibitors | 2000 | 138 | 61 | 56% |
| Novel Inhibitors of Inosine Monophosphate Dehydrogenase in Patent Literature of the Last Decade | 2013 | 6 | 88 | 77% |
| IMP dehydrogenase: structural schizophrenia and an unusual base | 2006 | 28 | 35 | 89% |
| Cofactor mimics as selective inhibitors of NAD-dependent inosine monophospate dehydrogenase (IMPDH) - the major therapeutic target | 2004 | 51 | 80 | 76% |
| Mycophenolic acid: A one hundred year odyssey from antibiotic to immunosuppressant | 2000 | 107 | 122 | 60% |
| Nucleoside and non-nucleoside IMP dehydrogenase inhibitors as antitumor and antiviral agents | 1999 | 82 | 81 | 80% |
| Targeting signal transduction | 2003 | 15 | 12 | 100% |
Address terms |
| Rank | Address term | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
|---|---|---|---|---|---|
| 1 | PESQUISAS BIOL MOL FUNC CPBMF | 1 | 33% | 0.2% | 2 |
| 2 | NEUROBIOL IMMUNOL | 1 | 10% | 0.7% | 7 |
| 3 | 4 NICKERSON ST | 1 | 50% | 0.1% | 1 |
| 4 | BIOSCI EASTERN CENT AFRICA BECA HUB | 1 | 50% | 0.1% | 1 |
| 5 | CATTEDRA EMATOL SERV AIDS | 1 | 50% | 0.1% | 1 |
| 6 | CNRS URA 1529 | 1 | 50% | 0.1% | 1 |
| 7 | FOR UNGS OR A | 1 | 50% | 0.1% | 1 |
| 8 | ICN GALENIKA | 1 | 50% | 0.1% | 1 |
| 9 | MED EXPTL ONCOL 702 BARNHILL DR | 1 | 50% | 0.1% | 1 |
| 10 | NYCOMED TAKEDA CO | 1 | 50% | 0.1% | 1 |
Related classes at same level (level 1) |
| Rank | Relatedness score | Related classes |
|---|---|---|
| 1 | 0.0000149381 | MIZORIBINE//COMPARAT TRANSPLANTAT//ORAL MIZORIBINE PULSE THERAPY |
| 2 | 0.0000134468 | CYCLOPENTENYL CYTOSINE//CTP SYNTHASE//CTP SYNTHETASE |
| 3 | 0.0000126601 | MYCOPHENOLIC ACID//MYCOPHENOLIC ACID GLUCURONIDE//MYCOPHENOLATE MOFETIL |
| 4 | 0.0000072759 | 2 3 DIKETO L GULONIC ACID//C NUCLEOSIDES//PYRAZOLO4 3 BPYRIDINE |
| 5 | 0.0000071271 | ADENYLOSUCCINATE LYASE DEFICIENCY//ADENYLOSUCCINATE LYASE//PURINE BIOSYNTHESIS |
| 6 | 0.0000061632 | IMMORTAL DNA//ADULT STEM CELL TECHNOL//IMMORTAL STRAND HYPOTHESIS |
| 7 | 0.0000056014 | PHOSPHORIBOSYLTRANSFERASE//MOL PARASITOL DRUG DESIGN//HGXPRT |
| 8 | 0.0000051938 | DIPYRIDAMOLE//VASODILATOR DRUG//TUMOR CELL GROWTH AND VIABILITY |
| 9 | 0.0000049537 | MN II CATALYSED//RIBAVIRIN TRIPHOSPHATE//M ANISIDINE |
| 10 | 0.0000045483 | URIDINE PHOSPHORYLASE//5 PHENYLTHIOACYCLOURIDINE//ALPHA D RIBOSE 1 PHOSPHATE |