Class information for:
Level 1: MONOMERIC INSULIN//INSULIN MUTANT//SINGLE CHAIN INSULIN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
10748 969 34.0 56%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1919 5291 RESTRICTION ENDONUCLEASE//RESTRICTION MODIFICATION//RESTRICTION MODIFICATION SYSTEM

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MONOMERIC INSULIN Author keyword 15 73% 1% 11
2 INSULIN MUTANT Author keyword 11 100% 1% 6
3 SINGLE CHAIN INSULIN Author keyword 6 80% 0% 4
4 FAST ACTING INSULIN Author keyword 6 100% 0% 4
5 STRUCTURE AND FUNCTION OF INSULIN Author keyword 3 100% 0% 3
6 DIABET PROT ENGN Address 3 31% 1% 8
7 INSULIN DERIVATIVE Author keyword 3 60% 0% 3
8 INSULIN HEXAMER Author keyword 3 60% 0% 3
9 ACHROMOBACTER LYTICUS PROTEASE Author keyword 2 67% 0% 2
10 GRPD Address 2 67% 0% 2

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 MONOMERIC INSULIN 15 73% 1% 11 Search MONOMERIC+INSULIN Search MONOMERIC+INSULIN
2 INSULIN MUTANT 11 100% 1% 6 Search INSULIN+MUTANT Search INSULIN+MUTANT
3 SINGLE CHAIN INSULIN 6 80% 0% 4 Search SINGLE+CHAIN+INSULIN Search SINGLE+CHAIN+INSULIN
4 FAST ACTING INSULIN 6 100% 0% 4 Search FAST+ACTING+INSULIN Search FAST+ACTING+INSULIN
5 STRUCTURE AND FUNCTION OF INSULIN 3 100% 0% 3 Search STRUCTURE+AND+FUNCTION+OF+INSULIN Search STRUCTURE+AND+FUNCTION+OF+INSULIN
6 INSULIN DERIVATIVE 3 60% 0% 3 Search INSULIN+DERIVATIVE Search INSULIN+DERIVATIVE
7 INSULIN HEXAMER 3 60% 0% 3 Search INSULIN+HEXAMER Search INSULIN+HEXAMER
8 ACHROMOBACTER LYTICUS PROTEASE 2 67% 0% 2 Search ACHROMOBACTER+LYTICUS+PROTEASE Search ACHROMOBACTER+LYTICUS+PROTEASE
9 HEXAMERIC INSULIN 2 67% 0% 2 Search HEXAMERIC+INSULIN Search HEXAMERIC+INSULIN
10 POSITIVE AND NEGATIVE COOPERATIVITY 2 67% 0% 2 Search POSITIVE+AND+NEGATIVE+COOPERATIVITY Search POSITIVE+AND+NEGATIVE+COOPERATIVITY

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MUTANT HUMAN INSULIN 61 86% 3% 31
2 STRUCTURAL SWITCH 41 85% 2% 22
3 RECEPTOR BINDING SURFACE 38 93% 1% 14
4 HALF SITE REACTIVITY 31 76% 2% 22
5 SHORTENED INSULIN 30 84% 2% 16
6 PHENYLALANINE B25 SIDE CHAIN 27 83% 2% 15
7 DISULFIDE FORMING PATHWAY 26 100% 1% 11
8 DES PENTAPEPTIDE INSULIN 25 73% 2% 19
9 HEXAMER 19 21% 8% 81
10 INVITRO POTENCY 19 71% 2% 15

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Proinsulin and the Genetics of Diabetes Mellitus 2009 26 70 60%
Insulin structure and function 2007 39 138 49%
Diabetes mellitus due to the toxic misfolding of proinsulin variants 2013 5 120 52%
Insulin: a small protein with a long journey 2010 14 101 66%
The in vitro oxidative folding of the insulin superfamily 2008 11 66 76%
Design of an active ultrastable single-chain insulin analog - Synthesis, structure, and therapeutic implications 2008 13 88 68%
Diabetes-associated mutations in human insulin: Crystal structure and photo-cross-linking studies of A-chain variant insulin Wakayama 2005 30 103 66%
THE STRUCTURE AND FUNCTION OF INSULIN: DECODING THE TR TRANSITION 2009 3 48 77%
STRUCTURE AND EVOLUTION OF INSULINS - IMPLICATIONS FOR RECEPTOR-BINDING 1992 79 27 59%
Insulin self-association and the relationship to pharmacokinetics and pharmacodynamics 2001 31 233 41%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 DIABET PROT ENGN 3 31% 0.8% 8
2 GRPD 2 67% 0.2% 2
3 S MED PHYS 1 100% 0.2% 2
4 UP 461 1 100% 0.2% 2
5 UP EA 3214 1 100% 0.2% 2
6 PREFORMULAT DELIVERY 1 40% 0.2% 2
7 DIABET PROT PEPTIDE CHEM 1 33% 0.2% 2
8 CMC DIABET ANAL FORMULAT 1 50% 0.1% 1
9 DIABET BRANCH BLDG 10 ROOM 85243 1 50% 0.1% 1
10 INSULIN CHEM 1 50% 0.1% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000183739 EXPT BIOTECHNOL PLANT//HUMAN CONSENSUS INTERFERON ALPHA//A21 DESAMIDOINSULIN
2 0.0000102291 GRP BIOPHYS MOL//BIOMOCETIUFR SMBH//UMR 8237
3 0.0000097354 LEPRECHAUNISM//INSULIN RECEPTOR//DONOHUE SYNDROME
4 0.0000095217 CONTINUOUS SUBCUTANEOUS INSULIN INFUSION//CSII//INSULIN PUMP
5 0.0000081097 BPTI//BAKER CHEM CHEM BIOL//SCRAMBLED PROTEINS
6 0.0000074240 NEONATAL DIABETES MELLITUS//NEONATAL DIABETES//WOLCOTT RALLISON SYNDROME
7 0.0000060158 PROINSULIN C PEPTIDE//C PEPTIDE//HUMAN C PEPTIDE
8 0.0000058177 PROINSULIN//INTACT PROINSULIN//SPLIT PROINSULIN
9 0.0000054626 INSULIN AUTOIMMUNE SYNDROME//INSULIN ALLERGY//INSULIN ANTIBODIES
10 0.0000052112 ORAL DELIVERY//ORAL INSULIN DELIVERY//ORAL INSULIN