Class information for:
Level 1: GRB2//SH2 DOMAIN//SH3 DOMAIN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
11658 900 44.6 89%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
313 17635 X LINKED AGAMMAGLOBULINEMIA//BRUTONS TYROSINE KINASE//BTK

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 GRB2 Author keyword 15 23% 6% 57
2 SH2 DOMAIN Author keyword 11 19% 6% 53
3 SH3 DOMAIN Author keyword 10 16% 7% 61
4 GRB2 SH2 Author keyword 9 83% 1% 5
5 GRB2 SH2 DOMAIN Author keyword 9 83% 1% 5
6 SH2 Author keyword 6 20% 3% 28
7 SH3 DOMAINS Author keyword 6 29% 2% 18
8 SH3 Author keyword 6 17% 3% 30
9 SH2 DOMAINS Author keyword 5 27% 2% 16
10 PHOSPHOTYROSYL MIMETIC Author keyword 4 75% 0% 3

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 GRB2 15 23% 6% 57 Search GRB2 Search GRB2
2 SH2 DOMAIN 11 19% 6% 53 Search SH2+DOMAIN Search SH2+DOMAIN
3 SH3 DOMAIN 10 16% 7% 61 Search SH3+DOMAIN Search SH3+DOMAIN
4 GRB2 SH2 9 83% 1% 5 Search GRB2+SH2 Search GRB2+SH2
5 GRB2 SH2 DOMAIN 9 83% 1% 5 Search GRB2+SH2+DOMAIN Search GRB2+SH2+DOMAIN
6 SH2 6 20% 3% 28 Search SH2 Search SH2
7 SH3 DOMAINS 6 29% 2% 18 Search SH3+DOMAINS Search SH3+DOMAINS
8 SH3 6 17% 3% 30 Search SH3 Search SH3
9 SH2 DOMAINS 5 27% 2% 16 Search SH2+DOMAINS Search SH2+DOMAINS
10 PHOSPHOTYROSYL MIMETIC 4 75% 0% 3 Search PHOSPHOTYROSYL+MIMETIC Search PHOSPHOTYROSYL+MIMETIC

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 AFFINITY PHOSPHOTYROSYL PEPTIDE 70 53% 10% 92
2 SRC HOMOLOGY 2 DOMAIN 37 42% 8% 68
3 ABL SH3 DOMAIN 33 77% 3% 23
4 PHOSPHATE CONTAINING LIGANDS 32 78% 2% 21
5 SH3 LIGAND INTERACTIONS 27 70% 3% 23
6 NONPHOSPHORYLATED INHIBITOR 21 90% 1% 9
7 PROLINE RICH PEPTIDES 20 34% 5% 48
8 TYROSINE PHOSPHORYLATED PEPTIDES 15 48% 3% 23
9 GRB2 SH2 DOMAIN 13 46% 2% 22
10 PHOSPHOTYROSINE RECOGNITION 13 71% 1% 10

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Modular peptide recognition domains in eukaryotic signaling 1997 388 99 51%
Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transduction 2005 221 101 30%
PROTEIN MODULES AND SIGNALING NETWORKS 1995 2017 111 24%
The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains 2000 775 137 22%
MODULAR BINDING DOMAINS IN SIGNAL-TRANSDUCTION PROTEINS 1995 875 66 41%
The SH2 domain: versatile signaling module and pharmaceutical target 2005 126 254 35%
SH3 domain ligand binding: What's the consensus and where's the specificity? 2012 23 28 46%
Can we infer peptide recognition specificity mediated by SH3 domains? 2002 90 28 64%
Evolving specificity from variability for protein interaction domains 2011 15 71 41%
Phosphotyrosyl mimetics in the development of signal transduction inhibitors 2003 70 74 43%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 VAKGRP COMP WETEN PEN 2 67% 0.2% 2
2 RAYMOND BEVERLY SACKLER GENET MOL MED 2 26% 0.8% 7
3 UM SYLVESTER BRAMAN FAMILY BREAST CANC 2 43% 0.3% 3
4 TEXAS DRUG DIAGNOST DEV 2 21% 0.8% 7
5 GWEN JULES KN P BIOMED DISCOVERY 1 100% 0.2% 2
6 UMR CNRS 8600 1 50% 0.2% 2
7 VET ADM FDN 1 100% 0.2% 2
8 FRE 2718 1 33% 0.3% 3
9 PHYS CHEM BIOCHEM INORGAN CHEM 1 25% 0.4% 4
10 STRUCT BIOL BIOMED SCI 1 30% 0.3% 3

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000205727 P66SHC//SHC//SHC FAMILY
2 0.0000171510 BIOL CHEMBUNKYO KU//DEMETHOXYVIRIDIN//2 4 MORPHOLINYL 8 PHENYLCHROMONE
3 0.0000163021 PHOSPHOPEPTIDE SYNTHESIS//DI T BUTYL N N DIETHYLPHOSPHORAMIDITE//GLOBAL PHOSPHORYLATION
4 0.0000143182 GRB7//GRB14//GRB10
5 0.0000140303 NEDD9//HEF1//CRK
6 0.0000107326 SLP 76//LINKER FOR ACTIVATION OF T CELLS//SECT LYMPHOCYTE SIGNALING
7 0.0000089456 SHP 2//SHP 1//GAB1
8 0.0000085405 SYK//SPLEEN TYROSINE KINASE//R788
9 0.0000084486 EPS8//MTSS1//I BAR
10 0.0000083480 VAV//VAV1//VAV3