Class information for:
Level 1: POLO LIKE KINASE 1//POLO BOX DOMAIN//PLK1

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
12147 864 43.6 93%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
388 16339 KINETOCHORE//MITOSIS//CENTROSOME

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 POLO LIKE KINASE 1 Author keyword 90 68% 9% 78
2 POLO BOX DOMAIN Author keyword 65 90% 3% 28
3 PLK1 Author keyword 63 47% 12% 101
4 POLO LIKE KINASE Author keyword 60 57% 8% 71
5 POLO LIKE KINASES Author keyword 29 75% 2% 21
6 BI 2536 Author keyword 18 67% 2% 16
7 PLK3 Author keyword 14 65% 2% 13
8 POLO BOX Author keyword 14 100% 1% 7
9 VOLASERTIB Author keyword 13 71% 1% 10
10 BI 6727 Author keyword 11 100% 1% 6

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 POLO LIKE KINASE 1 90 68% 9% 78 Search POLO+LIKE+KINASE+1 Search POLO+LIKE+KINASE+1
2 POLO BOX DOMAIN 65 90% 3% 28 Search POLO+BOX+DOMAIN Search POLO+BOX+DOMAIN
3 PLK1 63 47% 12% 101 Search PLK1 Search PLK1
4 POLO LIKE KINASE 60 57% 8% 71 Search POLO+LIKE+KINASE Search POLO+LIKE+KINASE
5 POLO LIKE KINASES 29 75% 2% 21 Search POLO+LIKE+KINASES Search POLO+LIKE+KINASES
6 BI 2536 18 67% 2% 16 Search BI+2536 Search BI+2536
7 PLK3 14 65% 2% 13 Search PLK3 Search PLK3
8 POLO BOX 14 100% 1% 7 Search POLO+BOX Search POLO+BOX
9 VOLASERTIB 13 71% 1% 10 Search VOLASERTIB Search VOLASERTIB
10 BI 6727 11 100% 1% 6 Search BI+6727 Search BI+6727

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PLK1 185 65% 20% 174
2 DROSOPHILA POLO 128 86% 7% 64
3 BI 2536 125 94% 5% 45
4 POLO LIKE KINASE 1 96 41% 21% 180
5 SACCHAROMYCES CEREVISIAE CDC5 93 88% 5% 44
6 PLK EXPRESSION 82 88% 4% 38
7 BOX DOMAIN 75 60% 9% 82
8 POLO LIKE KINASE 49 31% 15% 132
9 PLX1 48 73% 4% 37
10 PROTEIN SERINE THREONINE KINASE 36 83% 2% 20

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Discovery and development of the Polo-like kinase inhibitor volasertib in cancer therapy 2015 10 51 51%
Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy 2010 211 246 66%
Opinion - Targeting polo-like kinase 1 for cancer therapy 2006 387 119 73%
Polo-like kinases: conservation and divergence in their functions and regulation 2009 247 141 45%
Polo-like kinases and the orchestration of cell division 2004 557 119 55%
Polo-like kinases: structural variations lead to multiple functions 2014 18 199 36%
PLK1 as an oncology target: current status and future potential 2011 35 68 88%
Polo on the rise - from mitotic entry to cytokinesis with Plk1 2008 226 117 48%
Current clinical trials with polo-like kinase 1 inhibitors in solid tumors 2013 10 46 93%
Polo-like kinases and oncogenesis 2005 212 106 79%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 CELL CYCLE SIGNAL TRANSDUCT 4 56% 0.6% 5
2 CRC CELL CYCLE GENET GRP 2 67% 0.2% 2
3 DELAWARE CARDIOVASC 2 50% 0.3% 3
4 BIOL MECHANISMS SECT 1 100% 0.2% 2
5 CANC CAMPAIGN CELL CYCLE GENET GRP 1 50% 0.2% 2
6 GYNECOL MOL ONCOL GYNECOL 1 100% 0.2% 2
7 IMMUNE VASC CELL NETWORK 1 100% 0.2% 2
8 MOL DISCOVERY PROGRAM 1 19% 0.7% 6
9 PLUS GLOBAL REGENERAT MED BK21 1 40% 0.2% 2
10 CELL CYCLE GENET GRP 1 16% 0.6% 5

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000143685 UBCH10//ANAPHASE PROMOTING COMPLEX//GREATWALL
2 0.0000130240 AURORA A//AURORA KINASES//AURORA KINASE
3 0.0000103843 CYTOKINESIS//CLEAVAGE FURROW//CENTRALSPINDLIN
4 0.0000103420 STE20 LIKE KINASE//MAP4K4//STE20
5 0.0000103296 NIMA//NEK6//NEK2
6 0.0000100801 CENTROSOME//CENTRIOLE//CENTRIN
7 0.0000078953 KINETOCHORE//SPINDLE ASSEMBLY CHECKPOINT//MAD2
8 0.0000066913 CDC25B//CDC25A//AUTOSCHIZIS
9 0.0000065489 CYTOSTATIC FACTOR//MOS ONCOGENE//MPF
10 0.0000057455 CCNG2//CYCLIN G2//CYCLIN G