Class information for:
Level 1: IRON METAB CHELAT PROGRAM//PYRIDOXAL ISONICOTINOYL HYDRAZONE//TRIAPINE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
13643 759 44.6 74%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
141 22456 HEPCIDIN//HEMOCHROMATOSIS//IRON DEFICIENCY

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 IRON METAB CHELAT PROGRAM Address 35 54% 6% 45
2 PYRIDOXAL ISONICOTINOYL HYDRAZONE Author keyword 33 75% 3% 24
3 TRIAPINE Author keyword 23 69% 3% 20
4 3 AP Author keyword 21 90% 1% 9
5 3 AMINOPYRIDINE 2 CARBOXALDEHYDE THIOSEMICARBAZONE Author keyword 15 88% 1% 7
6 TRIAPINE R Author keyword 9 83% 1% 5
7 IRON CHELATOR Author keyword 8 17% 6% 42
8 IRON CHELATORS Author keyword 7 17% 5% 37
9 MOL PHARMACOL PATHOL PROGRAM Address 5 33% 2% 12
10 IRON METAB CHELAT GRP Address 4 36% 1% 9

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 PYRIDOXAL ISONICOTINOYL HYDRAZONE 33 75% 3% 24 Search PYRIDOXAL+ISONICOTINOYL+HYDRAZONE Search PYRIDOXAL+ISONICOTINOYL+HYDRAZONE
2 TRIAPINE 23 69% 3% 20 Search TRIAPINE Search TRIAPINE
3 3 AP 21 90% 1% 9 Search 3+AP Search 3+AP
4 3 AMINOPYRIDINE 2 CARBOXALDEHYDE THIOSEMICARBAZONE 15 88% 1% 7 Search 3+AMINOPYRIDINE+2+CARBOXALDEHYDE+THIOSEMICARBAZONE Search 3+AMINOPYRIDINE+2+CARBOXALDEHYDE+THIOSEMICARBAZONE
5 TRIAPINE R 9 83% 1% 5 Search TRIAPINE+R Search TRIAPINE+R
6 IRON CHELATOR 8 17% 6% 42 Search IRON+CHELATOR Search IRON+CHELATOR
7 IRON CHELATORS 7 17% 5% 37 Search IRON+CHELATORS Search IRON+CHELATORS
8 SALICYLALDEHYDE ISONICOTINOYL HYDRAZONE 3 50% 1% 5 Search SALICYLALDEHYDE+ISONICOTINOYL+HYDRAZONE Search SALICYLALDEHYDE+ISONICOTINOYL+HYDRAZONE
9 2 BENZOYLPYRIDINE 4 ETHYL 3 THIOSEMICARBAZONE 3 100% 0% 3 Search 2+BENZOYLPYRIDINE+4+ETHYL+3+THIOSEMICARBAZONE Search 2+BENZOYLPYRIDINE+4+ETHYL+3+THIOSEMICARBAZONE
10 BP4ET 3 100% 0% 3 Search BP4ET Search BP4ET

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 EFFECTIVE ANTIPROLIFERATIVE AGENTS 109 71% 12% 89
2 PYRIDOXAL ISONICOTINOYL HYDRAZONE 64 44% 14% 110
3 3 AMINOPYRIDINE 2 CARBOXALDEHYDE THIOSEMICARBAZONE 40 64% 5% 39
4 ANTINEUROBLASTOMA ACTIVITY 38 93% 2% 14
5 SELECTIVE ANTITUMOR ACTIVITY 30 54% 5% 39
6 RIBONUCLEOTIDE REDUCTASE INHIBITOR 28 50% 5% 41
7 OVERLOAD DISEASE 27 72% 3% 21
8 MALIGNANT MELANOMA CELL 25 77% 2% 17
9 IRON CHELATORS 18 16% 13% 102
10 ISONICOTINOYL HYDRAZONE CLASS 16 56% 3% 20

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
The evolution of iron chelators for the treatment of iron overload disease and cancer 2005 305 220 31%
Iron Chelators for the Treatment of Cancer 2012 28 128 45%
Iron and cancer: more ore to be mined 2013 70 184 16%
Thiosemicarbazones from the Old to New: Iron Chelators That Are More Than Just Ribonucleotide Reductase Inhibitors 2009 93 163 43%
Novel Chelators for Cancer Treatment: Where Are We Now? 2013 27 294 32%
Chelators at the cancer coalface: Desferrioxamine to triapine and beyond 2006 68 64 55%
Cancer cells with irons in the fire 2015 1 67 22%
Thiosemicarbazones: the new wave in cancer treatment 2009 26 33 79%
The role of iron in cell cycle progression and the proliferation of neoplastic cells 2002 222 155 28%
Iron Deprivation in Cancer-Potential Therapeutic Implications 2013 14 109 43%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 IRON METAB CHELAT PROGRAM 35 54% 5.9% 45
2 MOL PHARMACOL PATHOL PROGRAM 5 33% 1.6% 12
3 IRON METAB CHELAT GRP 4 36% 1.2% 9
4 RENAL INFECT DIS 2 43% 0.4% 3
5 OXYRAD GRP 2 24% 0.8% 6
6 CHIMIOSENSIBIL PALUDISME 1 100% 0.3% 2
7 IRON METABOL CHELAT PROGRAM 1 100% 0.3% 2
8 MET BIOL 1 12% 1.4% 11
9 METALS BIOL 1 33% 0.3% 2
10 CYTOL EXPT CANCEROL 1 23% 0.4% 3

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000180945 CHIM COORDINAT BIOORGAN BIOINORGAN//DESFERRIOXAMINE NITROXIDE RADICAL//SOY LIPOXYGENASE
2 0.0000139596 NDRG2//NDRG1//N MYC DOWNSTREAM REGULATED GENE 1
3 0.0000138769 HYDROXYPYRIDINONES//3 HYDROXYPYRIDIN 4 ONE//HYDROXYPYRIDINONE
4 0.0000136186 DEFERASIROX//IRON OVERLOAD//DEFERIPRONE
5 0.0000131596 FERRIC SORBITOL CITRATE//FERRIC SORBITOL CITRATE FSC//NF KAPPA B EXPRESSION ACTIVATION
6 0.0000115732 TRANSFERRIN//MELANOTRANSFERRIN//TRANSFERRIN RECEPTOR
7 0.0000103973 FERRIC NITRILOTRIACETATE//SECT CHEMOPREVENT NUTR TOXICOL//MED ELEMENTOL TOXICOL
8 0.0000095690 IRON RESPONSIVE ELEMENT//IRON REGULATORY PROTEINS//IRON REGULATORY PROTEIN 1
9 0.0000094888 THIOSEMICARBAZONE//THIOSEMICARBAZONES//THIOSEMICARBAZONE COMPLEXES
10 0.0000086283 RIBONUCLEOTIDE REDUCTASE//P53R2//TRIMIDOX