Class information for:
Level 1: HSP90//GELDANAMYCIN//HSP90 INHIBITORS

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
1409 2579 48.1 90%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
354 16848 HSP90//CHAPERONIN//HEAT SHOCK PROTEIN

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 HSP90 Author keyword 293 41% 21% 553
2 GELDANAMYCIN Author keyword 168 56% 8% 203
3 HSP90 INHIBITORS Author keyword 93 74% 3% 70
4 HEAT SHOCK PROTEIN 90 Author keyword 73 37% 6% 157
5 17 AAG Author keyword 67 60% 3% 74
6 HSP90 INHIBITOR Author keyword 66 66% 2% 61
7 CDC37 Author keyword 39 63% 2% 40
8 SNX 2112 Author keyword 35 89% 1% 16
9 RADICICOL Author keyword 32 50% 2% 46
10 17 ALLYLAMINO 17 DEMETHOXYGELDANAMYCIN Author keyword 27 76% 1% 19

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 HSP90 293 41% 21% 553 Search HSP90 Search HSP90
2 GELDANAMYCIN 168 56% 8% 203 Search GELDANAMYCIN Search GELDANAMYCIN
3 HSP90 INHIBITORS 93 74% 3% 70 Search HSP90+INHIBITORS Search HSP90+INHIBITORS
4 HEAT SHOCK PROTEIN 90 73 37% 6% 157 Search HEAT+SHOCK+PROTEIN+90 Search HEAT+SHOCK+PROTEIN+90
5 17 AAG 67 60% 3% 74 Search 17+AAG Search 17+AAG
6 HSP90 INHIBITOR 66 66% 2% 61 Search HSP90+INHIBITOR Search HSP90+INHIBITOR
7 CDC37 39 63% 2% 40 Search CDC37 Search CDC37
8 SNX 2112 35 89% 1% 16 Search SNX+2112 Search SNX+2112
9 RADICICOL 32 50% 2% 46 Search RADICICOL Search RADICICOL
10 17 ALLYLAMINO 17 DEMETHOXYGELDANAMYCIN 27 76% 1% 19 Search 17+ALLYLAMINO+17+DEMETHOXYGELDANAMYCIN Search 17+ALLYLAMINO+17+DEMETHOXYGELDANAMYCIN

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 GELDANAMYCIN 379 63% 15% 384
2 HEAT SHOCK PROTEIN 90 221 56% 10% 266
3 17 ALLYLAMINO 17 DEMETHOXYGELDANAMYCIN 208 74% 6% 153
4 SHOCK PROTEIN 90 204 68% 7% 181
5 HSP90 MOLECULAR CHAPERONE 155 61% 6% 165
6 MOLECULAR CHAPERONE HSP90 136 81% 3% 83
7 IMPORTANT BIOLOGIC ACTIVITIES 135 97% 1% 37
8 HSP90 128 25% 18% 452
9 ESCHERICHIA COLI HSP90 122 84% 3% 67
10 HEAT SHOCK PROTEIN 90 INHIBITORS 96 87% 2% 47

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Targeting the dynamic HSP90 complex in cancer 2010 471 156 65%
HSP90 at the hub of protein homeostasis: emerging mechanistic insights 2010 465 172 55%
HSP90 and the chaperoning of cancer 2005 1068 137 69%
Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers 2012 99 79 91%
Inhibition of HSP90 molecular chaperones: moving into the clinic 2013 56 62 81%
Structure and mechanism of the Hsp90 molecular chaperone machinery 2006 499 116 72%
HSP90 Inhibitors: Current Development and Potential in Cancer Therapy 2014 14 142 74%
The chaperone Hsp90: changing partners for demanding clients 2013 46 97 77%
Targeting the molecular chaperone heat shock protein 90 (HSP90): Lessons learned and future directions 2013 46 54 76%
The Hsp90 chaperone machinery 2008 271 73 78%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 SIGNAL TRANSDUCT MOL PHARMACOL TEAM 12 63% 0.5% 12
2 CANC UK CANC THER EUT 11 21% 1.7% 45
3 SECT STRUCT BIOL 9 20% 1.6% 42
4 PROGRAM MOL PHARMACOL CHEM 9 23% 1.2% 32
5 UROL ONCOL BRANCH 7 10% 2.4% 63
6 PHARMACEUT OPT SPECT 7 67% 0.2% 6
7 GUANGZHOU JINAN BIOMED DEV 5 33% 0.5% 12
8 HADDOW S 5 12% 1.4% 35
9 PROT FOLDING GRP 4 67% 0.2% 4
10 BIOMED RUMENTAT TECHNOL 4 75% 0.1% 3

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000176220 SANSALVAMIDE A//URUKTHAPELSTATIN A//PL EXPT GENOM
2 0.0000108616 SORCIN//TRAP1//HAISHENGSU
3 0.0000083748 BAG 1//BAG3//DR H BLISS MURPHY CANC
4 0.0000081773 DNAJ//GRPE//DNAK
5 0.0000074415 HSP27//HEAT SHOCK PROTEIN 27//CHAPERONOTHERAPY
6 0.0000074359 HYPOTHEMYCIN//RESORCYLIC ACID LACTONE//CURVULARIN
7 0.0000068880 HSF1//HEAT SHOCK FACTOR//HEAT SHOCK FACTOR 1
8 0.0000058123 GP96//IMMUNOTHER Y CANC INFECT DIS//CHAPEROKINE
9 0.0000056883 REPTIN//PONTIN//R2TP
10 0.0000053776 ACTINOSYNNEMA PRETIOSUM//ANSAMITOCINS//ANSAMITOCIN