Class information for:
Level 1: O 6 ALKYLGUANINE DNA ALKYLTRANSFERASE//O 6 BENZYLGUANINE//ALKYLTRANSFERASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
1472 2549 39.5 72%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2084 4777 O 6 ALKYLGUANINE DNA ALKYLTRANSFERASE//ALKYLTRANSFERASE//O 6 BENZYLGUANINE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 O 6 ALKYLGUANINE DNA ALKYLTRANSFERASE Author keyword 90 77% 2% 62
2 O 6 BENZYLGUANINE Author keyword 87 79% 2% 56
3 ALKYLTRANSFERASE Author keyword 87 83% 2% 49
4 O 6 METHYLGUANINE DNA METHYLTRANSFERASE Author keyword 81 55% 4% 102
5 O 6 METHYLGUANINE Author keyword 48 60% 2% 53
6 MGMT Author keyword 35 23% 5% 133
7 LOMEGUATRIB Author keyword 34 93% 1% 13
8 CANC UK CARCINOGENESIS GRP Address 31 61% 1% 33
9 O 6 ALKYLGUANINE Author keyword 27 92% 0% 11
10 ADA PROTEIN Author keyword 17 100% 0% 8

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 O 6 ALKYLGUANINE DNA ALKYLTRANSFERASE 90 77% 2% 62 Search O+6+ALKYLGUANINE+DNA+ALKYLTRANSFERASE Search O+6+ALKYLGUANINE+DNA+ALKYLTRANSFERASE
2 O 6 BENZYLGUANINE 87 79% 2% 56 Search O+6+BENZYLGUANINE Search O+6+BENZYLGUANINE
3 ALKYLTRANSFERASE 87 83% 2% 49 Search ALKYLTRANSFERASE Search ALKYLTRANSFERASE
4 O 6 METHYLGUANINE DNA METHYLTRANSFERASE 81 55% 4% 102 Search O+6+METHYLGUANINE+DNA+METHYLTRANSFERASE Search O+6+METHYLGUANINE+DNA+METHYLTRANSFERASE
5 O 6 METHYLGUANINE 48 60% 2% 53 Search O+6+METHYLGUANINE Search O+6+METHYLGUANINE
6 MGMT 35 23% 5% 133 Search MGMT Search MGMT
7 LOMEGUATRIB 34 93% 1% 13 Search LOMEGUATRIB Search LOMEGUATRIB
8 O 6 ALKYLGUANINE 27 92% 0% 11 Search O+6+ALKYLGUANINE Search O+6+ALKYLGUANINE
9 ADA PROTEIN 17 100% 0% 8 Search ADA+PROTEIN Search ADA+PROTEIN
10 O6 ALKYLGUANINE DNA ALKYLTRANSFERASE 15 73% 0% 11 Search O6+ALKYLGUANINE+DNA+ALKYLTRANSFERASE Search O6+ALKYLGUANINE+DNA+ALKYLTRANSFERASE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 O6 METHYLGUANINE DNA METHYLTRANSFERASE 313 78% 8% 205
2 O 6 ALKYLGUANINE DNA ALKYLTRANSFERASE 276 51% 15% 386
3 O6 BENZYLGUANINE 202 93% 3% 77
4 O6 ALKYLGUANINE DNA ALKYLTRANSFERASE 196 84% 4% 108
5 ALKYLATING AGENTS 179 27% 22% 562
6 HUMAN O6 ALKYLGUANINE DNA ALKYLTRANSFERASE 131 79% 3% 85
7 HUMAN O6 METHYLGUANINE DNA METHYLTRANSFERASE 117 93% 2% 43
8 O 6 METHYLGUANINE DNA METHYLTRANSFERASE 107 34% 10% 253
9 HUMAN O 6 METHYLGUANINE DNA METHYLTRANSFERASE 104 84% 2% 57
10 HUMAN O 6 ALKYLGUANINE DNA ALKYLTRANSFERASE 98 72% 3% 77

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
STRUCTURE, FUNCTION, AND INHIBITION OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE 1995 344 247 89%
MGMT: Its role in cancer aetiology and cancer therapeutics 2004 363 118 82%
MAMMALIAN O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE - REGULATION AND IMPORTANCE IN RESPONSE TO ALKYLATING CARCINOGENIC AND THERAPEUTIC AGENTS 1990 736 161 94%
Repair of O-6-alkylguanine by alkyltransferases 2000 351 135 84%
Balancing repair and tolerance of DNA damage caused by alkylating agents 2012 103 196 33%
MGMT: Key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents 2007 207 197 58%
Multifaceted Roles of Alkyltransferase and Related Proteins in DNA Repair, DNA Damage, Resistance to Chemotherapy, and Research Tools 2011 42 249 66%
Clinical relevance of MGMT in the treatment of cancer 2002 241 94 80%
O-6-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: Enzyme activity, promoter methylation and immunohistochemistry 2011 43 166 54%
Targeting O (6)-methylguanine-DNA methyltransferase with specific inhibitors as a strategy in cancer therapy 2010 41 134 85%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CANC UK CARCINOGENESIS GRP 31 61% 1.3% 33
2 PL TOXICOL 7 20% 1.1% 29
3 MED BIOREGULAT BIOCHEM 6 100% 0.2% 4
4 SECT GENOME DAMAGE REPAIR 4 30% 0.4% 11
5 CRC SECT GENOME DAMAGE REPAIR 3 57% 0.2% 4
6 MOL CELL BIOL CHEM CARCINOGENESIS 3 100% 0.1% 3
7 PATERSON CANC CARCINOGENESIS 3 100% 0.1% 3
8 TOXICOL PL TOXICOL 3 100% 0.1% 3
9 BEIJING ENVIRONM VIRAL ONCOL 3 45% 0.2% 5
10 CARCINOGENESIS GRP 3 28% 0.4% 9

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000168851 MTIC//DIPARTIMENTO FARMACOCHIM TOSSICOL BIOL//VLAK PROTOCOL
2 0.0000133888 ALKB//METTL3//ALKBH3
3 0.0000086764 SARCNU//TAUROMUSTINE//S 2250 KAWAGISHI
4 0.0000083079 IDH1//IDH2//ISOCITRATE DEHYDROGENASE 1
5 0.0000073286 VNP40101M//CLORETAZINE//NEW ANTICANCER AGENT
6 0.0000070970 N NITROSODIALKYLAMINE//N NITROSODIETHANOLAMINE//N NITROSO N METHYLANILINE
7 0.0000066997 BENZOYLATED DEAE CELLULOSE CHROMATOGRAPHY//POLYADENOSINE DIPHOSPHATE RIBOSE//N NITROSO N ETHYLUREA
8 0.0000066257 I COMPOUNDS//DNA ADDUCTS//P 32 POSTLABELING
9 0.0000064684 DNTP IMBALANCE//BLC 2//MICROBIAL TEST SYSTEMS
10 0.0000061384 APE1//AP ENDONUCLEASE//APE1 REF 1