Class information for:
Level 1: CYTOCHROME P450 INTERACTIONS//NONLINEAR CLEARANCE//NONLINEAR LIVER BINDING

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
14867 675 25.4 59%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1171 8982 ONYCHOMYCOSIS//DERMATOPHYTES//DERMATOPHYTOSIS

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 CYTOCHROME P450 INTERACTIONS Author keyword 1 50% 0% 2
2 NONLINEAR CLEARANCE Author keyword 1 50% 0% 2
3 NONLINEAR LIVER BINDING Author keyword 1 100% 0% 2
4 4 4 CHLOROBENZYLPYRIDINE Author keyword 1 50% 0% 1
5 ANTIFUNGAL MOUTHRINSE Author keyword 1 50% 0% 1
6 DRUG CONSULTAT CLIN PHARMACOL TOXICOL UNIT Address 1 50% 0% 1
7 ENZYME BLOCKERS Author keyword 1 50% 0% 1
8 GESTATIONAL PERIODS Author keyword 1 50% 0% 1
9 GYNECOMASTY Author keyword 1 50% 0% 1
10 INHIBITION OF STEROIDOGENESIS Author keyword 1 50% 0% 1

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class		 LCSH search Wikipedia search
1 CYTOCHROME P450 INTERACTIONS 1 50% 0% 2 Search CYTOCHROME+P450+INTERACTIONS Search CYTOCHROME+P450+INTERACTIONS
2 NONLINEAR CLEARANCE 1 50% 0% 2 Search NONLINEAR+CLEARANCE Search NONLINEAR+CLEARANCE
3 NONLINEAR LIVER BINDING 1 100% 0% 2 Search NONLINEAR+LIVER+BINDING Search NONLINEAR+LIVER+BINDING
4 4 4 CHLOROBENZYLPYRIDINE 1 50% 0% 1 Search 4+4+CHLOROBENZYLPYRIDINE Search 4+4+CHLOROBENZYLPYRIDINE
5 ANTIFUNGAL MOUTHRINSE 1 50% 0% 1 Search ANTIFUNGAL+MOUTHRINSE Search ANTIFUNGAL+MOUTHRINSE
6 ENZYME BLOCKERS 1 50% 0% 1 Search ENZYME+BLOCKERS Search ENZYME+BLOCKERS
7 GESTATIONAL PERIODS 1 50% 0% 1 Search GESTATIONAL+PERIODS Search GESTATIONAL+PERIODS
8 GYNECOMASTY 1 50% 0% 1 Search GYNECOMASTY Search GYNECOMASTY
9 INHIBITION OF STEROIDOGENESIS 1 50% 0% 1 Search INHIBITION+OF+STEROIDOGENESIS Search INHIBITION+OF+STEROIDOGENESIS
10 KETOCONAZOL 1 50% 0% 1 Search KETOCONAZOL Search KETOCONAZOL

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 HIGH DOSE KETOCONAZOLE 7 32% 3% 18
2 DOSE KETOCONAZOLE 6 42% 2% 11
3 IMIDAZOLE ANTIMYCOTIC AGENTS 4 67% 1% 4
4 SUBSTITUTED IMIDAZOLE 3 100% 0% 3
5 IMIDAZOLE ANTIFUNGAL AGENTS 3 60% 0% 3
6 LOW DOSE KETOCONAZOLE 2 32% 1% 6
7 N DEACETYL KETOCONAZOLE 2 40% 1% 4
8 1 BENZYLIMIDAZOLE 1 40% 0% 2
9 ORAL ANTIFUNGAL 1 40% 0% 2
10 INDUCED FULMINANT HEPATITIS 1 14% 1% 6

Journals

Reviews


Title Publ. year Cit. Active
references		 % act. ref.
to same field
Drug safety assessment of oral formulations of ketoconazole 2015 2 45 40%
DRUG-THERAPY - THE USE OF KETOCONAZOLE AS AN INHIBITOR OF STEROID-PRODUCTION 1987 255 68 87%
CLINICAL PHARMACOKINETICS OF KETOCONAZOLE 1988 140 81 51%
The treatment of advanced prostate cancer with ketoconazole - Safety issues 1999 11 31 74%
HIGH-DOSE KETOCONAZOLE FOR THE TREATMENT OF HORMONE REFRACTORY METASTATIC PROSTATE CARCINOMA - 16 CASES AND REVIEW OF THE LITERATURE 1989 30 12 58%
Ketoconazole Associated Hepatotoxicity: A Systematic Review and Meta-analysis 2013 5 9 22%
Inhibition of steroidogenesis by ketoconazole - Therapeutic uses 1997 10 95 67%
Ronald Estabrook's early guidance of a postdoctoral fellow concerning the intricacies of steroid metabolism by cytochromes P450 2007 0 4 75%
The Rise and Fall of Oral Ketoconazole 2015 0 28 54%
Treatment of oropharyngeal candidiasis and candidal diaper dermatitis in neonates and infants: review and reappraisal 1997 22 17 35%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 DRUG CONSULTAT CLIN PHARMACOL TOXICOL UNIT 1 50% 0.1% 1
2 NEUROENDOCRINE UNITHOSP CLIN 1 50% 0.1% 1
3 TERATOGENESE EXPT 1 50% 0.1% 1
4 UNIDAD ANALIT 405E 1 50% 0.1% 1
5 IMMEDIATE MED SERV 0 33% 0.1% 1
6 LAMPANG CANC HOSP 0 33% 0.1% 1
7 SERV MED INTERNE ENDOCRINOL B 0 33% 0.1% 1
8 MED INTERDISCIPLINARY IMMUNOL DIS 0 25% 0.1% 1
9 DRUG KINET GRP 0 20% 0.1% 1
10 INTEGRAT COMPLEMENTARY ALTERNAT MED DEV GRP 0 17% 0.1% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000218424 CONAZOLES//ZEBRAFISH EMBRYOTOXICITY TEST//TRIADIMEFON
2 0.0000210936 TOLNAFTATE//KETOCONAZOLE DETERMINATION//PIRIBEDIL
3 0.0000184629 SAPERCONAZOLE//BROMUCONAZOLE//MICONAZOLE SULFOSALICYLATE
4 0.0000144361 FLUCONAZOLE//FOSFLUCONAZOLE//MICRODILUTION TEST
5 0.0000108379 ONYCHOMYCOSIS//TERBINAFINE//TINEA PEDIS
6 0.0000079160 19 OXYGENATION//HUMAN PLACENTAL MICROSOME//HUMAN PLACENTAL MICROSOMES
7 0.0000071948 VULVO VAGINAL CANDIDIASIS//RECURRENT VULVOVAGINAL CANDIDIASIS//VAGINAL CANDIDIASIS
8 0.0000066069 FENTICONAZOLE//FARM IST MICROBIOL//FENTICONAZOLE NITRATE
9 0.0000064402 BLASTOMYCOSIS//BLASTOMYCES DERMATITIDIS//LYSATE ANTIGENS
10 0.0000063173 VORICONAZOLE//HYDROXYITRACONAZOLE//POSACONAZOLE