Class information for:
Level 1: PYRROLOBENZODIAZEPINE//PYRROLOBENZODIAZEPINES//PYRROLO2 1 C1 4BENZODIAZEPINES

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
15070 664 28.6 65%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2357 3920 DUOCARMYCINS//PYRROLOBENZODIAZEPINE//PYRROLE IMIDAZOLE POLYAMIDE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PYRROLOBENZODIAZEPINE Author keyword 73 88% 5% 35
2 PYRROLOBENZODIAZEPINES Author keyword 55 87% 4% 27
3 PYRROLO2 1 C1 4BENZODIAZEPINES Author keyword 45 94% 2% 16
4 CANC UK GENE TARGETED DRUG DESIGN GRP Address 38 89% 3% 17
5 GENE TARGETED DRUG DESIGN GRP Address 26 80% 2% 16
6 SPIROGEN LTD Address 21 90% 1% 9
7 SJG 136 Author keyword 18 89% 1% 8
8 GENE TARGETING DRUG DESIGN GRP Address 12 86% 1% 6
9 PYRROLO2 1 C1 4BENZODIAZEPINE Author keyword 11 100% 1% 6
10 CRC GENE TARGETED DRUG DESIGN GRP Address 8 100% 1% 5

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 PYRROLOBENZODIAZEPINE 73 88% 5% 35 Search PYRROLOBENZODIAZEPINE Search PYRROLOBENZODIAZEPINE
2 PYRROLOBENZODIAZEPINES 55 87% 4% 27 Search PYRROLOBENZODIAZEPINES Search PYRROLOBENZODIAZEPINES
3 PYRROLO2 1 C1 4BENZODIAZEPINES 45 94% 2% 16 Search PYRROLO2+1+C1+4BENZODIAZEPINES Search PYRROLO2+1+C1+4BENZODIAZEPINES
4 SJG 136 18 89% 1% 8 Search SJG+136 Search SJG+136
5 PYRROLO2 1 C1 4BENZODIAZEPINE 11 100% 1% 6 Search PYRROLO2+1+C1+4BENZODIAZEPINE Search PYRROLO2+1+C1+4BENZODIAZEPINE
6 PBDS 8 100% 1% 5 Search PBDS Search PBDS
7 DNA BINDING ABILITY 8 62% 1% 8 Search DNA+BINDING+ABILITY Search DNA+BINDING+ABILITY
8 DNA BINDING AFFINITY 6 35% 2% 15 Search DNA+BINDING+AFFINITY Search DNA+BINDING+AFFINITY
9 ANTHRAMYCIN 6 58% 1% 7 Search ANTHRAMYCIN Search ANTHRAMYCIN
10 DC 81 6 100% 1% 4 Search DC+81 Search DC+81

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ANTHRAMYCIN 112 78% 11% 74
2 TOMAYMYCIN 93 91% 6% 39
3 PYRROLO1 4BENZODIAZEPINE ANTITUMOR ANTIBIOTICS 62 80% 6% 39
4 SIBIROMYCIN 49 94% 3% 17
5 PYRROLOBENZODIAZEPINE DIMERS 47 88% 3% 22
6 SPECTRUM ANTITUMOR ACTIVITY 42 83% 4% 24
7 PYRROLO2 1 C1 4BENZODIAZEPINES 39 74% 4% 29
8 SJG 136 NSC 694501 31 82% 3% 18
9 DC 81 27 65% 4% 26
10 PYRROLO2 1 C1 4BENZODIAZEPINE 22 81% 2% 13

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Synthesis of DNA-Interactive Pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) 2011 35 191 87%
Biosynthesis, synthesis, and biological activities of pyrrolobenzodiazepines 2012 17 130 85%
Pyrrolo[2,1-c][1,4]benzodiazepine as a Scaffold for the Design and Synthesis of Anti-Tumour Drugs 2009 35 125 67%
The development of pyrrolobenzodiazepines as antitumour agents 2011 18 59 73%
SYNTHESIS OF DNA-INTERACTIVE PYRROLO[2,1-C][1,4]BENZODIAZEPINES 1994 219 102 77%
Search for New and Novel Chemotherapeutics for the Treatment of Human Malignancies 2010 14 215 39%
Recent advances in the solid-phase combinatorial synthetic strategies for the benzodiazepine based privileged structures 2006 42 69 30%
The newer synthetic strategies for DNA binding pyrrolobenzodiazepine antibiotics 1998 7 35 91%
Synthetic Strategies Applicable in the Synthesis of Privileged Scaffold: 1,4-Benzodiazepine 2014 3 77 19%
Apoptosis-inducing agents: a patent review (2010-2013) 2014 4 13 15%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CANC UK GENE TARGETED DRUG DESIGN GRP 38 89% 2.6% 17
2 GENE TARGETED DRUG DESIGN GRP 26 80% 2.4% 16
3 SPIROGEN LTD 21 90% 1.4% 9
4 GENE TARGETING DRUG DESIGN GRP 12 86% 0.9% 6
5 CRC GENE TARGETED DRUG DESIGN GRP 8 100% 0.8% 5
6 CR UK DRUG DNA INTERACT GRP 5 60% 0.9% 6
7 YORKSHIRE CANC DRUG DESIGN 5 43% 1.4% 9
8 QMB INNOVAT 4 75% 0.5% 3
9 EA IMT 6306 3 100% 0.5% 3
10 UATRS ANGLE ALLAL FASSI FAR 3 100% 0.5% 3

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000184979 1 RUE VAUBENARD//UER SCI PHARMACEUT//TRIPENTONE
2 0.0000111452 DUOCARMYCINS//CC 1065//DUOCARMYCIN
3 0.0000090640 1 5 BENZODIAZEPINES//1 5 BENZODIAZEPINE//O PHENYLENEDIAMINES
4 0.0000084354 PYRROLE IMIDAZOLE POLYAMIDE//DISTAMYCIN//MINOR GROOVE BINDERS
5 0.0000074969 DRUG DESIGN SYNTH//GUANINE DEAMINASE//GUANASE
6 0.0000067503 NITRILIMINE CYCLOADDITION//3A 7A DIHYDROINDAZOLES//STUDIO RELAZ STRUTT REATTIV CHIM
7 0.0000059038 1 2 3 4 TETRAHYDROPYRAZINO1 2 AINDOLES//BENZOFUROPYRIDINE//IODOLACTONISATION
8 0.0000053815 SHARPLESS CONDITIONS//FLUOROORGAN//3H PYRIMIDIN 4 ONE
9 0.0000045029 ORGAN SYNTH GRP//4 HYDROXY 2 OXO 1 2 DIHYDROQUINOLINE 3 CARBOXAMIDES//4 HYDROXY 2 OXO 1 2 DIHYDROQUINOLINE 3 CARBOXYLIC ACIDS
10 0.0000044234 COMMUNESIN//PEROPHORAMIDINE//FLUSTRA FOLIACEA