Class information for:
Level 1: AICARDI GOUTIERES SYNDROME//TREX1//RIBONUCLEASE H

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
15325 648 37.0 80%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2321 4046 VELOCARDIOFACIAL SYNDROME//DIGEORGE SYNDROME//PSEUDOHYPOPARATHYROIDISM

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 AICARDI GOUTIERES SYNDROME Author keyword 108 86% 8% 55
2 TREX1 Author keyword 22 67% 3% 20
3 RIBONUCLEASE H Author keyword 13 33% 5% 33
4 NEUROGENET NEUROINFLAMMAT Address 7 67% 1% 6
5 AICARDI GOUTIERES Author keyword 6 80% 1% 4
6 FAMILIAL CHILBLAIN LUPUS Author keyword 6 80% 1% 4
7 GEN NEUROL COMPLEX MOTOR DISORDERS SERV Address 6 80% 1% 4
8 RNASE H1 Author keyword 6 71% 1% 5
9 RNASE H2 Author keyword 6 71% 1% 5
10 INTRACRANIAL CALCIFICATION Author keyword 6 28% 3% 18

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 AICARDI GOUTIERES SYNDROME 108 86% 8% 55 Search AICARDI+GOUTIERES+SYNDROME Search AICARDI+GOUTIERES+SYNDROME
2 TREX1 22 67% 3% 20 Search TREX1 Search TREX1
3 RIBONUCLEASE H 13 33% 5% 33 Search RIBONUCLEASE+H Search RIBONUCLEASE+H
4 AICARDI GOUTIERES 6 80% 1% 4 Search AICARDI+GOUTIERES Search AICARDI+GOUTIERES
5 FAMILIAL CHILBLAIN LUPUS 6 80% 1% 4 Search FAMILIAL+CHILBLAIN+LUPUS Search FAMILIAL+CHILBLAIN+LUPUS
6 RNASE H1 6 71% 1% 5 Search RNASE+H1 Search RNASE+H1
7 RNASE H2 6 71% 1% 5 Search RNASE+H2 Search RNASE+H2
8 INTRACRANIAL CALCIFICATION 6 28% 3% 18 Search INTRACRANIAL+CALCIFICATION Search INTRACRANIAL+CALCIFICATION
9 RNASE H 6 15% 5% 35 Search RNASE+H Search RNASE+H
10 RNASE HII 6 100% 1% 4 Search RNASE+HII Search RNASE+HII

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PROGRESSIVE FAMILIAL ENCEPHALOPATHY 83 84% 7% 46
2 CEREBROSPINAL FLUID LYMPHOCYTOSIS 68 84% 6% 37
3 FAMILIAL CHILBLAIN LUPUS 52 72% 6% 41
4 MOLECULAR DIVERSITIES 49 94% 3% 17
5 AICARDI GOUTIERES SYNDROME 37 32% 15% 97
6 INFECTION LIKE SYNDROME 35 89% 2% 16
7 EXONUCLEASE TREX1 33 53% 7% 43
8 RNHB GENE 30 100% 2% 12
9 DNA EXONUCLEASE TREX1 18 56% 3% 22
10 RNASE H2 18 89% 1% 8

Journals

Reviews


Title Publ. year Cit. Active
references		 % act. ref.
to same field
Type I interferonopathies: Mendelian type I interferon up-regulation 2015 10 41 54%
Ribonuclease H: the enzymes in eukaryotes 2009 138 42 79%
Therapies in Aicardi-Goutieres syndrome 2014 13 35 77%
Aicardi-Goutieres syndrome: an important Mendelian mimic of congenital infection 2008 38 19 95%
Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity 2009 96 67 46%
Ribonuclease H: molecular diversities, substrate binding domains, and catalytic mechanism of the prokaryotic enzymes 2009 50 57 70%
Aicardi-Goutieres syndrome: a model disease for systemic autoimmunity 2014 16 79 38%
Aicardi-Goutieres syndrome 2005 34 29 86%
Aicardi-Goutieres syndrome, a rare neurological disease in children: A new autoimmune disorder? 2013 2 22 100%
Aicardi-GoutiSres syndrome: clues from the RNase H2 knock-out mouse 2013 4 49 71%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 NEUROGENET NEUROINFLAMMAT 7 67% 0.9% 6
2 GEN NEUROL COMPLEX MOTOR DISORDERS SERV 6 80% 0.6% 4
3 CENT MANCHESTER FDN TRUST UNIV HOSP 2 33% 0.9% 6
4 CHILD NEUROL PSYCHIAT UNIT 1 10% 2.2% 14
5 UNIT CHILD NEUROL PSYCHIAT 1 15% 1.4% 9
6 MANCHESTER GENOM MED HUMAN DEV 1 38% 0.5% 3
7 AFULA R P ORT MED 1 50% 0.3% 2
8 BRADFORD CHILD DEV 1 100% 0.3% 2
9 SKAGGS CHEM BIOL MB4 1 100% 0.3% 2
10 CORE ANTISENSE 1 24% 0.6% 4

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000121830 VPR//VPX//HIV 1 VPR
2 0.0000106616 FAHRS DISEASE//BASAL GANGLIA CALCIFICATION//FAHRS SYNDROME
3 0.0000084187 FEN1//BRAUN S//CREAT INITIAT CELL CYCLE CONTROL
4 0.0000082478 ERYTHEMA AB IGNE//CHILBLAINS//PERNIO
5 0.0000078404 PROGRAM BIOCHEM CHEM//RNA CRYSTALLOGRAPHY//5 METHYL CYTIDINE
6 0.0000075723 NNRTIS//REVERSE TRANSCRIPTASE//HIV 1 REVERSE TRANSCRIPTASE
7 0.0000069225 ZINC PROTEINS//DRUG DESIGN BIOTECHNOL//METALLOPROTEOME
8 0.0000067229 STAPHYLOCOCCAL NUCLEASE//THERMODYNAMIC MOLECULAR SWITCH//PROTEIN THERMOSTABILITY
9 0.0000061643 PONTOSUBICULAR NECROSIS//INFANTILE BILATERAL STRIATAL NECROSIS//BRAINSTEM NECROSIS
10 0.0000054068 UNC93B1//MARY KIRKLAND LUPUS//TLR7