Class information for:
Level 1: DUOCARMYCINS//CC 1065//DUOCARMYCIN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
15823 621 38.4 74%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2357 3920 DUOCARMYCINS//PYRROLOBENZODIAZEPINE//PYRROLE IMIDAZOLE POLYAMIDE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 DUOCARMYCINS Author keyword 61 88% 5% 29
2 CC 1065 Author keyword 51 83% 5% 29
3 DUOCARMYCIN Author keyword 48 77% 5% 33
4 ADOZELESIN Author keyword 45 94% 3% 16
5 BIZELESIN Author keyword 34 93% 2% 13
6 DUOCARMYCIN SA Author keyword 20 100% 1% 9
7 KW 2189 Author keyword 14 100% 1% 7
8 CARZELESIN Author keyword 12 86% 1% 6
9 DUOCARMYCIN A Author keyword 6 80% 1% 4
10 CC 1065 ANTITUMOR ANTIBIOTIC Author keyword 3 100% 0% 3

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 DUOCARMYCINS 61 88% 5% 29 Search DUOCARMYCINS Search DUOCARMYCINS
2 CC 1065 51 83% 5% 29 Search CC+1065 Search CC+1065
3 DUOCARMYCIN 48 77% 5% 33 Search DUOCARMYCIN Search DUOCARMYCIN
4 ADOZELESIN 45 94% 3% 16 Search ADOZELESIN Search ADOZELESIN
5 BIZELESIN 34 93% 2% 13 Search BIZELESIN Search BIZELESIN
6 DUOCARMYCIN SA 20 100% 1% 9 Search DUOCARMYCIN+SA Search DUOCARMYCIN+SA
7 KW 2189 14 100% 1% 7 Search KW+2189 Search KW+2189
8 CARZELESIN 12 86% 1% 6 Search CARZELESIN Search CARZELESIN
9 DUOCARMYCIN A 6 80% 1% 4 Search DUOCARMYCIN+A Search DUOCARMYCIN+A
10 CC 1065 ANTITUMOR ANTIBIOTIC 3 100% 0% 3 Search CC+1065+ANTITUMOR+ANTIBIOTIC Search CC+1065+ANTITUMOR+ANTIBIOTIC

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 LEFT HAND SUBUNIT 193 89% 14% 88
2 NONCOVALENT BINDING SELECTIVITY 192 98% 8% 49
3 CC 1065 168 64% 26% 163
4 DNA ALKYLATION PROPERTIES 157 100% 7% 42
5 ENHANCED FUNCTIONAL ANALOGS 131 88% 10% 61
6 ANTITUMOR ANTIBIOTIC CC 1065 108 75% 12% 77
7 CC 1065 NSC 298223 98 84% 9% 53
8 BENZANNELATED ANALOG 93 100% 5% 28
9 NSC 298223 91 94% 5% 32
10 ELECTROPHILE REACTIVITY 89 100% 4% 27

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
CC-1065 and the duocarmycins: Understanding their biological function through mechanistic studies 1996 222 184 91%
CC-1065 and the duocarmycins: Synthetic studies 1997 177 201 78%
Shape-dependent catalysis: Insights into the source of catalysis for the CC-1065 and duocarmycin DNA alkylation reaction 1999 86 49 98%
Yatakemycin: total synthesis, DNA alkylation, and biological properties 2008 17 20 95%
CC-1065 AND THE DUOCARMYCINS - UNRAVELING THE KEYS TO A NEW CLASS OF NATURALLY DERIVED DNA ALKYLATING-AGENTS 1995 119 69 90%
DNA minor groove binders: Back in the groove 2009 33 85 39%
THE DUOCARMYCINS - SYNTHETIC AND MECHANISTIC STUDIES 1995 82 70 97%
Chemical and Biological Explorations of the Family of CC-1065 and the Duocarmycin Natural Products 2009 11 145 74%
Prodrugs for Targeted Tumor Therapies: Recent Developments in ADEPT, GDEPT and PMT 2011 26 151 27%
Duocarmycins - Natures prodrugs? 2002 23 60 80%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 DNA INTERACT GRP 3 60% 0.5% 3
2 CANC UK DRUG 2 67% 0.3% 2
3 AUCKLAND SOC 1 50% 0.2% 1
4 BIOSCI ORGAN 1 50% 0.2% 1
5 NEW MOL ENT 1 50% 0.2% 1
6 TTPA 1 50% 0.2% 1
7 MATH ECON INFORMAT SCI 0 33% 0.2% 1
8 ADVANCING MED INNOVAT 0 25% 0.2% 1
9 CANC CAMPAIGN DRUG DNA INTERACT GRP 0 25% 0.2% 1
10 UPS TAAM CIPA 44 0 25% 0.2% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000181282 PYRROLE IMIDAZOLE POLYAMIDE//DISTAMYCIN//MINOR GROOVE BINDERS
2 0.0000158767 CB1954//ADEPT//ANTIBODY DIRECTED ENZYME PRODRUG THERAPY
3 0.0000111452 PYRROLOBENZODIAZEPINE//PYRROLOBENZODIAZEPINES//PYRROLO2 1 C1 4BENZODIAZEPINES
4 0.0000107210 PI CONJUGATED ORGANIC COMPOUND//RIBBON LIKE MOLECULAR ARRANGEMENT//2 AMINOMETHYL 5 HYDROXY 1H INDOLE 3 CARBOXYLIC ACIDS
5 0.0000085016 IROFULVEN//MGI 114//HMAF
6 0.0000061966 ANTIBODY DRUG CONJUGATE//ANTIBODY DRUG CONJUGATES//T DM1
7 0.0000045910 ANTHROSE//SECT CARBOHYDRATES//VIBRIO CHOLERAE O 1
8 0.0000044941 2 HYDRAZONOPHENYLTHIOACETAMIDES//6 AZAURACILS//1 ARYL 6 AZACYTOSINE
9 0.0000042633 COUNTING RESIDUES//B3LYP 6 31GD METHOD//CATIONIC SIGMA COMPLEXES
10 0.0000042122 AZAINDOLES//7 AZAINDOLES//2 ETHYNYLANILINE