Class information for:
Level 1: ACYL GLUCURONIDES//ACYL GLUCURONIDE//ZOMEPIRAC

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
16464 587 33.5 64%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2272 4206 BIOANALYSIS//LC NMR//DRIED BLOOD SPOT DBS

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ACYL GLUCURONIDES Author keyword 18 61% 3% 19
2 ACYL GLUCURONIDE Author keyword 11 42% 4% 21
3 ZOMEPIRAC Author keyword 9 67% 1% 8
4 ACYLGLUCURONIDE Author keyword 7 64% 1% 7
5 GLUCURONATES Author keyword 4 50% 1% 6
6 ROMAZARIT Author keyword 4 75% 1% 3
7 DRUG PROTEIN ADDUCTS Author keyword 4 46% 1% 6
8 CLEARANCE RENAL Author keyword 3 60% 1% 3
9 DRUG PROTEIN ADDUCT Author keyword 2 67% 0% 2
10 NAPROXEN PHARMACOKINETICS Author keyword 2 67% 0% 2

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 ACYL GLUCURONIDES 18 61% 3% 19 Search ACYL+GLUCURONIDES Search ACYL+GLUCURONIDES
2 ACYL GLUCURONIDE 11 42% 4% 21 Search ACYL+GLUCURONIDE Search ACYL+GLUCURONIDE
3 ZOMEPIRAC 9 67% 1% 8 Search ZOMEPIRAC Search ZOMEPIRAC
4 ACYLGLUCURONIDE 7 64% 1% 7 Search ACYLGLUCURONIDE Search ACYLGLUCURONIDE
5 GLUCURONATES 4 50% 1% 6 Search GLUCURONATES Search GLUCURONATES
6 ROMAZARIT 4 75% 1% 3 Search ROMAZARIT Search ROMAZARIT
7 DRUG PROTEIN ADDUCTS 4 46% 1% 6 Search DRUG+PROTEIN+ADDUCTS Search DRUG+PROTEIN+ADDUCTS
8 CLEARANCE RENAL 3 60% 1% 3 Search CLEARANCE++RENAL Search CLEARANCE++RENAL
9 DRUG PROTEIN ADDUCT 2 67% 0% 2 Search DRUG+PROTEIN+ADDUCT Search DRUG+PROTEIN+ADDUCT
10 NAPROXEN PHARMACOKINETICS 2 67% 0% 2 Search NAPROXEN+PHARMACOKINETICS Search NAPROXEN+PHARMACOKINETICS

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ZOMEPIRAC GLUCURONIDE 45 83% 4% 25
2 ACYL GLUCURONIDES 41 46% 11% 67
3 ZOMEPIRAC 31 62% 5% 32
4 1 O ACYL GLUCURONIDE 24 82% 2% 14
5 BILIRUBIN GLUCURONIDES 18 89% 1% 8
6 1 BETA O ACYL GLUCURONIDES 17 75% 2% 12
7 INTERNAL ACYL MIGRATION 17 100% 1% 8
8 SCHIFF BASE MECHANISM 15 77% 2% 10
9 IRREVERSIBLE BINDING 15 25% 9% 51
10 COA THIOESTER 14 100% 1% 7

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Acyl Glucuronides: The Good, The Bad and The Ugly 2010 46 171 42%
ACYL GLUCURONIDES REVISITED - IS THE GLUCURONIDATION PROCESS A TOXIFICATION AS WELL AS A DETOXIFICATION MECHANISM 1992 324 78 55%
Acyl glucuronide drug metabolites: Toxicological and analytical implications 2003 146 144 58%
Metabolic activation of carboxylic acids 2008 48 96 58%
Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity 2003 165 91 44%
Structure-Activity Relationships for Degradation Reaction of 1-beta-O-Acyl Glucuronides: Kinetic Description and Prediction of Intrinsic Electrophilic Reactivity under Physiological Conditions 2009 15 90 67%
Iso-glucuronides 2011 5 53 94%
Acyl glucuronides: Biological activity, chemical reactivity, and chemical synthesis 2006 39 141 55%
Acyl glucuronide reactivity in perspective: biological consequences 2003 123 114 46%
Drug-S-Acyl-Glutathione Thioesters: Synthesis, Bioanalytical Properties, Chemical Reactivity, Biological Formation and Degradation 2011 8 78 54%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ROBERT ROBINSON S 2 11% 2.4% 14
2 STUDIES DRUG DISPOSIT 1 22% 0.9% 5
3 AMSTERDAM MOL MEDICINES SYST 1 50% 0.2% 1
4 ASTRAZENECA UK LTD 1 50% 0.2% 1
5 BIOANAL PHARMACOKINET 1 50% 0.2% 1
6 CNRS 2843 1 50% 0.2% 1
7 CSDD 1 50% 0.2% 1
8 DISCOVER CHEM 1 50% 0.2% 1
9 DMPK IM 1 22% 0.3% 2
10 LEAD DISCOVERY OPTIMIZAT S 0 33% 0.2% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000258892 REACTIVE METABOLITE//MASS DEFECT FILTER//TIENILIC ACID
2 0.0000202504 CHIRAL INVERSION//DEXIBUPROFEN//FLOBUFEN
3 0.0000179814 CORTISOL METABOLITE//GLUCRONIDE//PHAMACOL THER EUT
4 0.0000081952 UDP GLUCURONOSYLTRANSFERASE//UGT1A1//GLUCURONIDATION
5 0.0000077814 DRUG INDUCED LIVER INJURY//HERB INDUCED LIVER INJURY//HYS LAW
6 0.0000076622 ACECLOFENAC//MEFENAMIC ACID//CAS 15307 86 5
7 0.0000073751 INO 2628 CZ//DOUBLE PEAKS//DISCONTINUOUS ABSORPTION
8 0.0000069482 FLAVONE ACETIC ACID//DMXAA//5 6 DIMETHYLXANTHENONE 4 ACETIC ACID
9 0.0000064484 ALPHA NAPHTHYLISOTHIOCYANATE//IDIOSYNCRATIC DRUG INDUCED LIVER INJURY//IDIOSYNCRATIC ADVERSE DRUG REACTIONS
10 0.0000061773 SALICYLURIC ACID//SALICYLATE POISONING//SALICYLATE DETERMINATION