Class information for:
Level 1: BRYOSTATIN 1//BRYOSTATIN//BRYOSTATINS

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
17043 557 43.3 82%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1002 9892 PHOSPHOLIPASE D//DIACYLGLYCEROL KINASE//PROTEIN KINASE C

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 BRYOSTATIN 1 Author keyword 77 65% 13% 73
2 BRYOSTATIN Author keyword 55 61% 10% 58
3 BRYOSTATINS Author keyword 27 78% 3% 18
4 APLYSIATOXIN Author keyword 9 55% 2% 11
5 MARINE BRYOZOAN Author keyword 6 58% 1% 7
6 BUGULA NERITINA Author keyword 4 28% 2% 13
7 BRYOSTATIN 11 Author keyword 3 100% 1% 3
8 AURISTATIN PE Author keyword 3 50% 1% 4
9 BRYOSTATIN 5 Author keyword 2 67% 0% 2
10 PKC ACTIVATORS Author keyword 2 67% 0% 2

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 BRYOSTATIN 1 77 65% 13% 73 Search BRYOSTATIN+1 Search BRYOSTATIN+1
2 BRYOSTATIN 55 61% 10% 58 Search BRYOSTATIN Search BRYOSTATIN
3 BRYOSTATINS 27 78% 3% 18 Search BRYOSTATINS Search BRYOSTATINS
4 APLYSIATOXIN 9 55% 2% 11 Search APLYSIATOXIN Search APLYSIATOXIN
5 MARINE BRYOZOAN 6 58% 1% 7 Search MARINE+BRYOZOAN Search MARINE+BRYOZOAN
6 BUGULA NERITINA 4 28% 2% 13 Search BUGULA+NERITINA Search BUGULA+NERITINA
7 BRYOSTATIN 11 3 100% 1% 3 Search BRYOSTATIN+11 Search BRYOSTATIN+11
8 AURISTATIN PE 3 50% 1% 4 Search AURISTATIN+PE Search AURISTATIN+PE
9 BRYOSTATIN 5 2 67% 0% 2 Search BRYOSTATIN+5 Search BRYOSTATIN+5
10 PKC ACTIVATORS 2 67% 0% 2 Search PKC+ACTIVATORS Search PKC+ACTIVATORS

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PYRAN ANNULATION 53 95% 3% 18
2 ACTIVATOR BRYOSTATIN 1 29 88% 3% 14
3 POTENT ANTINEOPLASTIC AGENTS 26 100% 2% 11
4 C 17 C 27 FRAGMENT 23 100% 2% 10
5 AGENT BRYOSTATIN 1 20 100% 2% 9
6 INTRAVENOUS BRYOSTATIN 1 18 89% 1% 8
7 CLONOGENIC RESPONSE 17 100% 1% 8
8 BRYOSTATIN 1 16 30% 8% 45
9 C1 C9 SEGMENT 14 100% 1% 7
10 BUGULA NERITINA 12 36% 5% 27

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
The Chemistry and Biology of the Bryostatins: Potential PKC Inhibitors in Clinical Development 2012 17 102 74%
Bryostatin-1: A novel PKC inhibitor in clinical development 2003 81 107 72%
New Approaches to the Total Synthesis of the Bryostatin Antitumor Macrolides 2010 50 160 63%
Total synthesis of bryostatin 2 1999 193 101 51%
Chemistry and clinical biology of the bryostatins 2000 127 82 67%
Function-oriented synthesis, step economy, and drug design 2008 388 56 27%
The chemistry and biology of the bryostatin antitumour macrolides 2002 127 145 47%
The clinical development of the bryostatins 2002 62 67 78%
Function through Synthesis-Informed Design 2015 2 38 32%
Marine natural products: Bryostatins in preclinical and clinical studies 2014 5 29 72%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 INTERNAL MEDKARMANOS CANC 2 50% 0.5% 3
2 HEMATOL ONCOLKARMANOS CANC 1 30% 0.5% 3
3 EXPTL CHEMOTHER Y 1 50% 0.2% 1
4 HAEMATOL BR238 1 50% 0.2% 1
5 MASS SPE OMETER IL 1 50% 0.2% 1
6 NAT RADIAT PONSE MECHANISMS GRP 1 50% 0.2% 1
7 GASTROINTESTINAL ONCOL NEW DRUG DEV 0 33% 0.2% 1
8 MASS SPEC 0 33% 0.2% 1
9 MED HEM ONC 0 33% 0.2% 1
10 PHASE 2 NETWORK 0 33% 0.2% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000203650 ENZASTAURIN//C1 DOMAIN//INDOLACTAM
2 0.0000165001 DOLASTATIN 10//DIDEMNIN B//TZT 1027
3 0.0000114083 UCN 01//7 HYDROXYSTAUROSPORINE//7 HYDROXYSTAUROSPORINE UCN 01
4 0.0000103224 PROTEIN KINASE C ISOFORMS//PROTEIN KINASE C ISOZYMES//PROTEIN KINASE C SUBSPECIES
5 0.0000101758 PRINS CYCLIZATION//CENTROLOBINE//PRINS CYCLISATION
6 0.0000084644 AS101//SAFDIE AIDS IMMUNOL//CAIR
7 0.0000079697 DCP LA//ALPHA 7 ACH RECEPTOR//ALPHA 7 ACETYLCHOLINE RECEPTOR
8 0.0000069281 PAEDERUS//PEDERIN//PAEDERUS DERMATITIS
9 0.0000066326 REDUCTION DIASTEREOSELECTIVE//ALDOL PRODUCTS//HYDROXY AMIDES
10 0.0000050169 PERIPHERAL CELLS//GERIATR MEDKFC//NORMAL HUMAN SKIN FIBROBLASTS