Class information for:
Level 1: ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT//ANTISENSE RESEARCH AND DEVELOPMENT//ANTISENSE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
1713 2442 39.4 80%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
77 26633 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//NUCLEOSIDES & NUCLEOTIDES//NUCLEOSIDES

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT Journal 54 34% 5% 128
2 ANTISENSE RESEARCH AND DEVELOPMENT Journal 38 60% 2% 42
3 ANTISENSE Author keyword 26 11% 9% 229
4 PHOSPHOROTHIOATE Author keyword 23 31% 3% 63
5 ANTISENSE OLIGONUCLEOTIDES Author keyword 21 15% 5% 126
6 OLIGONUCLEOTIDE Author keyword 11 10% 4% 107
7 ANTISENSE OLIGONUCLEOTIDE Author keyword 9 11% 3% 77
8 ANTISENSE IMAGING Author keyword 6 80% 0% 4
9 PHOSPHOROTHIOATE OLIGONUCLEOTIDE Author keyword 6 45% 0% 10
10 OLIGODEOXYNUCLEOTIDES Author keyword 5 16% 1% 30

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 ANTISENSE 26 11% 9% 229 Search ANTISENSE Search ANTISENSE
2 PHOSPHOROTHIOATE 23 31% 3% 63 Search PHOSPHOROTHIOATE Search PHOSPHOROTHIOATE
3 ANTISENSE OLIGONUCLEOTIDES 21 15% 5% 126 Search ANTISENSE+OLIGONUCLEOTIDES Search ANTISENSE+OLIGONUCLEOTIDES
4 OLIGONUCLEOTIDE 11 10% 4% 107 Search OLIGONUCLEOTIDE Search OLIGONUCLEOTIDE
5 ANTISENSE OLIGONUCLEOTIDE 9 11% 3% 77 Search ANTISENSE+OLIGONUCLEOTIDE Search ANTISENSE+OLIGONUCLEOTIDE
6 ANTISENSE IMAGING 6 80% 0% 4 Search ANTISENSE+IMAGING Search ANTISENSE+IMAGING
7 PHOSPHOROTHIOATE OLIGONUCLEOTIDE 6 45% 0% 10 Search PHOSPHOROTHIOATE+OLIGONUCLEOTIDE Search PHOSPHOROTHIOATE+OLIGONUCLEOTIDE
8 OLIGODEOXYNUCLEOTIDES 5 16% 1% 30 Search OLIGODEOXYNUCLEOTIDES Search OLIGODEOXYNUCLEOTIDES
9 ANTISENSE OLIGODEOXYNUCLEOTIDES 5 15% 1% 29 Search ANTISENSE+OLIGODEOXYNUCLEOTIDES Search ANTISENSE+OLIGODEOXYNUCLEOTIDES
10 EXONUCLEASE RESISTANCE 4 67% 0% 4 Search EXONUCLEASE+RESISTANCE Search EXONUCLEASE+RESISTANCE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 OLIGODEOXYNUCLEOTIDES 95 19% 19% 462
2 PHOSPHOROTHIOATE OLIGODEOXYNUCLEOTIDES 88 41% 7% 165
3 OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATES 56 76% 2% 39
4 ANTISENSE OLIGONUCLEOTIDES 43 12% 14% 348
5 PHOSPHOROTHIOATE OLIGONUCLEOTIDES 38 34% 4% 93
6 C 14 LABELED PHOSPHOROTHIOATE OLIGONUCLEOTIDE 37 73% 1% 29
7 CHRONICALLY INFECTED CELLS 37 57% 2% 44
8 PHOSPHOROTHIOATE OLIGONUCLEOTIDE 37 48% 2% 56
9 C ALPHA EXPRESSION 26 58% 1% 30
10 OLIGODEOXYRIBONUCLEOSIDE METHYLPHOSPHONATES 25 52% 1% 34

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT 54 34% 5% 128
2 ANTISENSE RESEARCH AND DEVELOPMENT 38 60% 2% 42

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Progress in antisense technology 2004 286 125 66%
Antisense oligonucleotides: Basic concepts and mechanisms 2002 288 111 59%
A review of issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides 1999 269 72 65%
ANTISENSE OLIGONUCLEOTIDES AS THERAPEUTIC AGENTS - IS THE BULLET REALLY MAGICAL 1993 1223 122 52%
PHARMACOKINETICS OF ANTISENSE OLIGONUCLEOTIDES 1995 197 11 100%
Nucleic-acid therapeutics: Basic principles and recent applications 2002 304 127 35%
Antisense oligonucleotides: Promise and reality 2001 177 74 61%
Antisense oligonucleotide pharmacokinetics and metabolism 2009 58 59 59%
Antisense therapeutics 1998 174 30 63%
Importance of nucleotide sequence and chemical modifications of antisense oligonucleotides 1999 147 84 69%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 CHEM G 838 5 63% 0.2% 5
2 CHIM THER EUT RADIOPHARM 2 67% 0.1% 2
3 GRP DRUG TARGETING DELIVERY POORLY STABLE CPDS 2 67% 0.1% 2
4 UCL 7541 2 67% 0.1% 2
5 ASTON GENE BASED THER EUT 1 100% 0.1% 2
6 JIANGXI OAI GEMEINSAMES 1 100% 0.1% 2
7 STELLAR CHANCE S 513B 1 100% 0.1% 2
8 UCL 7340 1 50% 0.1% 2
9 CARLSBAD 1 20% 0.2% 5
10 IFR PATHOL INFECT 1 24% 0.2% 4

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000149784 SYNTHET BIOORGAN CHEM//NUCLE ACID//NUCL ACID
2 0.0000142549 OLIGONUCLEOTIDE DERIVATIVES//NOVOSIBIRSK BIOORGAN CHEM//PHOTOAFFINITY MODIFICATION
3 0.0000139099 OLIGONUCLEOTIDE PEPTIDE CONJUGATE//PEPTIDE OLIGONUCLEOTIDE CONJUGATE//OLIGONUCLEOTIDE PEPTIDE CONJUGATES
4 0.0000130955 L DNA//HETEROCHIRAL DNA//UMR CNRS UMII 5625
5 0.0000127691 EXON SKIPPING//DMD GENET THER Y GRP//MC LOCKWOOD MUSCULAR DYSTROPHY
6 0.0000125999 BORANOPHOSPHATE//PHOSPHONOFLUORIDATE//BORANOPHOSPHONATE
7 0.0000086647 TRIPLEX DNA//DNA TRIPLEX//TRIPLEX
8 0.0000084192 H PHOSPHONATES//OLIGONUCLEOTIDE SYNTHESIS//UNIVERSAL SOLID SUPPORT
9 0.0000077384 TRANSCRIPTION FACTOR DECOY//DECOY//DECOY OLIGODEOXYNUCLEOTIDE
10 0.0000073439 COLD INDUCED HYPERTENSION//ANTISENSE ELEMENTS//AT1 RECEPTOR ANTISENSE