Class information for:
Level 1: 2 METHOXYESTRADIOL//2 METHOXYOESTRADIOL//2 METHOXYESTRADIOL BIS SULPHAMATE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
18181 500 36.9 85%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2508 3401 2 METHOXYESTRADIOL//INDOLE 3 CARBINOL//3 3 DIINDOLYLMETHANE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 2 METHOXYESTRADIOL Author keyword 206 72% 33% 163
2 2 METHOXYOESTRADIOL Author keyword 17 79% 2% 11
3 2 METHOXYESTRADIOL BIS SULPHAMATE Author keyword 11 100% 1% 6
4 2 METHOXYESTRADIOL 2ME2 Author keyword 9 83% 1% 5
5 ESTRADIOL METABOLITES Author keyword 9 52% 2% 12
6 MED CHEM STERIX LTD Address 8 70% 1% 7
7 STERIX LTD Address 7 28% 4% 21
8 ENDOCRINOL METAB MED STERIX LTD Address 7 53% 2% 9
9 2 METHOXYESTRADIOL ANALOGS Author keyword 6 100% 1% 4
10 2 ME Author keyword 4 67% 1% 4

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 2 METHOXYESTRADIOL 206 72% 33% 163 Search 2+METHOXYESTRADIOL Search 2+METHOXYESTRADIOL
2 2 METHOXYOESTRADIOL 17 79% 2% 11 Search 2+METHOXYOESTRADIOL Search 2+METHOXYOESTRADIOL
3 2 METHOXYESTRADIOL BIS SULPHAMATE 11 100% 1% 6 Search 2+METHOXYESTRADIOL+BIS+SULPHAMATE Search 2+METHOXYESTRADIOL+BIS+SULPHAMATE
4 2 METHOXYESTRADIOL 2ME2 9 83% 1% 5 Search 2+METHOXYESTRADIOL+2ME2 Search 2+METHOXYESTRADIOL+2ME2
5 ESTRADIOL METABOLITES 9 52% 2% 12 Search ESTRADIOL+METABOLITES Search ESTRADIOL+METABOLITES
6 2 METHOXYESTRADIOL ANALOGS 6 100% 1% 4 Search 2+METHOXYESTRADIOL+ANALOGS Search 2+METHOXYESTRADIOL+ANALOGS
7 2 ME 4 67% 1% 4 Search 2+ME Search 2+ME
8 ESE 16 3 100% 1% 3 Search ESE+16 Search ESE+16
9 2 METHOXYESTRADIOL 2 ME 2 67% 0% 2 Search 2+METHOXYESTRADIOL+2+ME Search 2+METHOXYESTRADIOL+2+ME
10 OESTROGEN SULPHAMATES 2 67% 0% 2 Search OESTROGEN+SULPHAMATES Search OESTROGEN+SULPHAMATES

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ENDOGENOUS ESTROGEN METABOLITE 98 71% 16% 79
2 ENDOGENOUS MAMMALIAN METABOLITE 86 71% 14% 70
3 MAMMALIAN METABOLITE 60 83% 7% 34
4 INHIBITS TUBULIN POLYMERIZATION 58 73% 9% 45
5 ORAL 2 METHOXYESTRADIOL 28 68% 5% 25
6 2 METHOXYOESTRADIOL 27 83% 3% 15
7 MULTITARGETED ANTITUMOR AGENTS 24 91% 2% 10
8 2 METHOXYOESTRADIOL BIS SULFAMATE 23 100% 2% 10
9 METHOXYESTRADIOLS MEDIATE 23 74% 3% 17
10 2 METHOXYESTRADIOL 22 30% 13% 63

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
2-Methoxyestradiol-Biology and mechanism of action 2010 67 76 75%
2-methoxyestradiol - a unique blend of activities generating a new class of anti-tumour/anti-inflammatory agents 2007 50 54 70%
Synthetic 2-Methoxyestradiol Derivatives: Structure-Activity Relationships 2012 8 131 82%
Therapeutic Promises of 2-Methoxyestradiol and Its Drug Disposition Challenges 2010 28 48 67%
2-Methoxyestradiol and Disorders of Female Reproductive Tissues 2014 2 89 61%
Potential vascular actions of 2-methoxyestradiol 2009 25 45 64%
Mechanism of action of 2-methoxyestradiol: new developments 2003 115 38 71%
2-methoxyestradiol: An endogenous antiangiogenic and antiproliferative drug candidate 2000 168 31 65%
2-methoxyestradiol, a promising anticancer agent 2003 154 51 43%
Synthesis of sex hormone-derived modified steroids possessing antiproliferative activity 2013 7 72 32%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MED CHEM STERIX LTD 8 70% 1.4% 7
2 STERIX LTD 7 28% 4.2% 21
3 ENDOCRINOL METAB MED STERIX LTD 7 53% 1.8% 9
4 PHARM PHARMACOL STERIX LTD 4 75% 0.6% 3
5 SECT ENDOCRINOL MENOPAUSE 2 22% 1.8% 9
6 PRECLIN PHARMA 68 209 2 67% 0.4% 2
7 CELLULAR DIFFERENTIAT TRANSFORMAT 1 100% 0.4% 2
8 MCKNIGHT 1 50% 0.4% 2
9 REPROD IMMUNOL PHARMACOL 1 100% 0.4% 2
10 SCEENING TECHNOL BRANCH 1 100% 0.4% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000233552 ESTRADIOL 17 SULFATE//KATSURAOKA CHO 71//CATECHOLESTROGENS
2 0.0000115649 DEPURINATING ESTROGEN DNA ADDUCTS//INDENESTROL A//CATECHOL ESTROGENS
3 0.0000106153 INDOLE 3 CARBINOL//3 3 DIINDOLYLMETHANE//16 ALPHA HYDROXYESTRONE
4 0.0000089010 STEROID SULFATASE//ESTRONE SULFATASE//AROMATASE
5 0.0000068018 COMBRETASTATIN//COMBRETASTATIN A 4//COMBRETASTATINS
6 0.0000063208 D HOMOSTEROIDS//FUSED STEROIDS//16 17 SECOSTEROIDS
7 0.0000058017 SPONTANEOUS PROTEINURIA//STUDY SEX DIFFERENCES HLTH AGING DIS//SEX GENDER DIFFERENCES HLTH DIS
8 0.0000051778 HEMATOL ONCOLWINSHIP CANC//MICROTUBULE ACTIVE DRUGS//PHARMACOLRAMMELKAMP EDUC
9 0.0000046296 CARBOXYAMIDOTRIAZOLE//CARBOXYAMIDO TRIAZOLE//PROOFREADING STIMULATION
10 0.0000043286 FLUOROESTRADIOL//F 18 FES PET//FES PET