Class information for:
Level 1: APOLIPOPROTEIN E//APOE//APOLIPOPROTEIN E4

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
1834 2395 48.1 88%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
14 37098 ALZHEIMERS DISEASE//AMYLOID PRECURSOR PROTEIN//BETA AMYLOID

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 APOLIPOPROTEIN E Author keyword 244 26% 34% 822
2 APOE Author keyword 48 19% 10% 229
3 APOLIPOPROTEIN E4 Author keyword 21 44% 2% 37
4 APOLIPOPROTEIN E APOE Author keyword 8 26% 1% 27
5 491 A T POLYMORPHISM Author keyword 6 80% 0% 4
6 APOE EPSILON 4 ALLELE Author keyword 6 44% 0% 11
7 APOE PROMOTER Author keyword 6 58% 0% 7
8 APOLIPOPROTEIN E GENOTYPE Author keyword 6 27% 1% 19
9 TARGETED REPLACEMENT MICE Author keyword 6 100% 0% 4
10 APOE GENOTYPE Author keyword 6 19% 1% 26

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 APOLIPOPROTEIN E 244 26% 34% 822 Search APOLIPOPROTEIN+E Search APOLIPOPROTEIN+E
2 APOE 48 19% 10% 229 Search APOE Search APOE
3 APOLIPOPROTEIN E4 21 44% 2% 37 Search APOLIPOPROTEIN+E4 Search APOLIPOPROTEIN+E4
4 APOLIPOPROTEIN E APOE 8 26% 1% 27 Search APOLIPOPROTEIN+E+APOE Search APOLIPOPROTEIN+E+APOE
5 491 A T POLYMORPHISM 6 80% 0% 4 Search 491+A+T+POLYMORPHISM Search 491+A+T+POLYMORPHISM
6 APOE EPSILON 4 ALLELE 6 44% 0% 11 Search APOE+EPSILON+4+ALLELE Search APOE+EPSILON+4+ALLELE
7 APOE PROMOTER 6 58% 0% 7 Search APOE+PROMOTER Search APOE+PROMOTER
8 APOLIPOPROTEIN E GENOTYPE 6 27% 1% 19 Search APOLIPOPROTEIN+E+GENOTYPE Search APOLIPOPROTEIN+E+GENOTYPE
9 TARGETED REPLACEMENT MICE 6 100% 0% 4 Search TARGETED+REPLACEMENT+MICE Search TARGETED+REPLACEMENT+MICE
10 APOE GENOTYPE 6 19% 1% 26 Search APOE+GENOTYPE Search APOE+GENOTYPE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 TYPE 4 ALLELE 233 48% 15% 358
2 E GENOTYPE 214 46% 14% 345
3 E POLYMORPHISM 92 29% 11% 274
4 ISOFORM SPECIFIC BINDING 81 80% 2% 51
5 EPSILON 4 ALLELE 73 36% 7% 161
6 E IMMUNOREACTIVITY 70 79% 2% 45
7 E MESSENGER RNA 68 51% 4% 97
8 APOE GENOTYPE 66 31% 8% 182
9 ISOFORM SPECIFIC INTERACTIONS 61 88% 1% 29
10 E ALLELE EPSILON 4 55 54% 3% 71

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ALZHEIMERS REPORTS 2 12% 1% 16

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease - A meta-analysis 1997 1525 64 81%
The Role of Apolipoprotein E in Alzheimer's Disease 2009 383 229 68%
Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy 2013 156 166 50%
Apolipoprotein E4: A causative factor and therapeutic target in neuropathology including Alzheimer's disease 2006 416 155 65%
Apolipoprotein E in Alzheimer's disease and other neurological disorders 2011 183 164 57%
ApoE and A beta in Alzheimer's Disease: Accidental Encounters or Partners? 2014 31 156 46%
Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy 2009 317 144 42%
Alzheimer Mechanisms and Therapeutic Strategies 2012 276 192 25%
Soluble apoE/A beta complex: mechanism and therapeutic target for APOE4-induced AD risk 2014 11 102 71%
Apolipoprotein E in Alzheimer's Disease: An Update 2014 14 130 58%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MULTIDISCIPLINARY NEUROPROTECT 4 67% 0.2% 4
2 GLADSTONE NEUROL DIS 4 13% 1.2% 28
3 BRYAN ALZHEIMERS DIS 3 31% 0.4% 9
4 JOSEPH KATHLEEN BRYAN ALZHEIMERS DIS 3 16% 0.7% 16
5 HOPE NEUROL DISORDERS NEUROL 3 60% 0.1% 3
6 NEUROSYMPTOMAT DISORDERS 3 60% 0.1% 3
7 R DAVID THOMAS EXECUT TRAINING 3 60% 0.1% 3
8 STUDY NERVOUS SYST INJURY 2 11% 0.8% 20
9 HOSP MOINHOS VENTO PORTO ALEGRE 2 67% 0.1% 2
10 PHYSIOLNEUROSCI 2 67% 0.1% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000247853 ALPHA 1 ANTICHYMOTRYPSIN//D10S1423//PSYCHIATGERONTOL UNIT
2 0.0000187627 LIPOPROTEIN GLOMERULOPATHY//APOLIPOPROTEIN E//TYPE III HYPERLIPOPROTEINEMIA
3 0.0000143985 AMYLOID PRECURSOR PROTEIN GENE//BRAIN INJURY DEMENTIA//FAMILIAL ALZHEIMER
4 0.0000136107 24S HYDROXYCHOLESTEROL//CYP46//24 HYDROXYCHOLESTEROL
5 0.0000129727 SORL1//TOMM40//PICALM
6 0.0000118990 SECT ENDOCRINOL DIABET METAB MC 797//CHOLESTEROL RICH DIETS//APOLIPOPROTEIN E ISOFORMS
7 0.0000081634 APOLIPOPROTEIN D//APOLIPOPROTEIN D APOD//APOD
8 0.0000079406 LRP1B//VLDL RECEPTOR//LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN
9 0.0000077668 HERPES SIMPLEX TYPE 1 VIRUS//INT ALZHEIMER//CX340
10 0.0000063739 BETA A4 DEPOSITS//SENILE PLAQUES//NEUROFIBRILLARY TANGLES