Class information for:
Level 1: FRUCTOSE 1 6 BISPHOSPHATASE//FBPASE//MUSCLE FBPASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
18422 487 30.2 55%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2368 3860 PHOSPHOFRUCTOKINASE//GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE//6 PHOSPHOFRUCTO 2 KINASE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FRUCTOSE 1 6 BISPHOSPHATASE Author keyword 18 29% 11% 53
2 FBPASE Author keyword 12 53% 3% 16
3 MUSCLE FBPASE Author keyword 11 100% 1% 6
4 AMP INHIBITION Author keyword 6 80% 1% 4
5 GLYCONEOGENESIS Author keyword 6 41% 2% 11
6 ANIM MOL PHYSIOL Address 5 32% 2% 12
7 DISCOVERY BASEL Address 4 67% 1% 4
8 FRUCTOSE 1 6 BISPHOSPHATASE DEFICIENCY Author keyword 4 75% 1% 3
9 FRUCTOSE 1 6 DIPHOSPHATASE Author keyword 3 60% 1% 3
10 AMP ACTIVATION Author keyword 2 67% 0% 2

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 FRUCTOSE 1 6 BISPHOSPHATASE 18 29% 11% 53 Search FRUCTOSE+1+6+BISPHOSPHATASE Search FRUCTOSE+1+6+BISPHOSPHATASE
2 FBPASE 12 53% 3% 16 Search FBPASE Search FBPASE
3 MUSCLE FBPASE 11 100% 1% 6 Search MUSCLE+FBPASE Search MUSCLE+FBPASE
4 AMP INHIBITION 6 80% 1% 4 Search AMP+INHIBITION Search AMP+INHIBITION
5 GLYCONEOGENESIS 6 41% 2% 11 Search GLYCONEOGENESIS Search GLYCONEOGENESIS
6 FRUCTOSE 1 6 BISPHOSPHATASE DEFICIENCY 4 75% 1% 3 Search FRUCTOSE+1+6+BISPHOSPHATASE+DEFICIENCY Search FRUCTOSE+1+6+BISPHOSPHATASE+DEFICIENCY
7 FRUCTOSE 1 6 DIPHOSPHATASE 3 60% 1% 3 Search FRUCTOSE+1+6+DIPHOSPHATASE Search FRUCTOSE+1+6+DIPHOSPHATASE
8 AMP ACTIVATION 2 67% 0% 2 Search AMP+ACTIVATION Search AMP+ACTIVATION
9 AMP MIMETIC 2 67% 0% 2 Search AMP+MIMETIC Search AMP+MIMETIC
10 GLYCEROLURIA 2 67% 0% 2 Search GLYCEROLURIA Search GLYCEROLURIA

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PIG KIDNEY FRUCTOSE 1 6 BISPHOSPHATASE 94 97% 6% 28
2 RABBIT LIVER FRUCTOSE 1 6 BISPHOSPHATASE 76 100% 5% 24
3 FRUCTOSE 1 6 BISPHOSPHATASE 60 37% 27% 130
4 1 6 BISPHOSPHATASE 55 77% 8% 37
5 BISPHOSPHATASE 50 76% 7% 35
6 AMP INHIBITION 48 100% 3% 17
7 LIVER FRUCTOSE 1 6 BISPHOSPHATASE 47 88% 5% 22
8 DYNAMIC LOOP 41 100% 3% 15
9 BENZOXAZOLE BENZENESULFONAMIDES 38 93% 3% 14
10 NEUTRAL FORM 34 93% 3% 13

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Localization and regulation of muscle fructose-1,6-bisphosphatase, the key enzyme of glyconeogenesis 2006 9 74 57%
REVERSIBLE ENZYME-INHIBITORS AS MECHANISTIC PROBES 1995 12 3 100%
Discovery of fructose-1,6-bisphosphatase inhibitors for the treatment of type 2 diabetes 2007 11 32 44%
Discovery of potent and specific fructose-1,6-bisphosphatase inhibitors and a series of orally-bioavailable phosphoramidase-sensitive prodrugs for the treatment of type 2 diabetes 2007 36 91 18%
Enzymes involved in L-lactate metabolism in humans 2013 5 152 14%
MECHANISM OF ACTION OF FRUCTOSE 1,6-BISPHOSPHATASE 1982 191 10 70%
LIGAND-BINDING TO PROTEINS BY EQUILIBRIUM GEL PENETRATION 1985 9 2 100%
Organophosphonic acids as drug candidates 2006 7 36 19%
Are biological sensors modulated by their structural scaffolds? The role of the structural muscle proteins alpha-actinin-2 and alpha-actinin-3 as modulators of biological sensors 2010 6 84 12%
IMMOBILIZATION OF NUCLEOSIDE DIPHOSPHATASE AT THE ALLOSTERIC SITE USING PYRIDOXAL 5'-PHOSPHATE DERIVATIVES 1987 0 1 100%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ANIM MOL PHYSIOL 5 32% 2.5% 12
2 DISCOVERY BASEL 4 67% 0.8% 4
3 BIOCHEM MOL MODELING 1 50% 0.4% 2
4 CIENCIAS BIOQUIM CASILLA 567 1 50% 0.2% 1
5 CORE EVOLUTIONAL SCI TECHNOL PROGRAM 1 50% 0.2% 1
6 EXPLORATORY S I 1 50% 0.2% 1
7 STRUCT PROTE TORONTO 1 50% 0.2% 1
8 GENET CELL PHYSIOL 0 20% 0.4% 2
9 MED CHEM S 1 0 10% 0.8% 4
10 OBES DIABET INNOVAT 0 33% 0.2% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000271006 6 PHOSPHOFRUCTO 2 KINASE//6 PHOSPHOFRUCTO 2 KINASE FRUCTOSE 2 6 BISPHOSPHATASE//FRUCTOSE 2 6 BISPHOSPHATE
2 0.0000101839 THIOREDOXIN H//PHOSPHORIBULOKINASE//CP12
3 0.0000090153 GLYCEROL KINASE DEFICIENCY//COMPLEX GLYCEROL KINASE DEFICIENCY//KOHLSCHUTTER TONZ SYNDROME
4 0.0000074168 ECOM//ENZIMOL CONTROLE METAB//ONCOBIOL MOL OMOL
5 0.0000062819 ALDOLASE//CLASS II ALDOLASE//FRUCTOSE 1 6 BISPHOSPHATE ALDOLASE
6 0.0000045718 BIPHASIC ACTIVATION//DSPE//BIOMATH TOXICOL UNIT
7 0.0000045161 CA COMPLEX//IY POSTOVSKII ORGAN SYNTH//VINYL PHOSPHONATE
8 0.0000044460 FROG OOCYTE//FROG OOCYTES//MAT NAT SUBST ENVIRONM MODELING
9 0.0000043180 SUCROSE PHOSPHATE SYNTHASE//SUCROSE PHOSPHATE PHOSPHATASE//SUCROSE SYNTHESIS
10 0.0000041535 GLUCOSE REPRESSION//CATABOLITE INACTIVATION//MIG1