Class information for:
Level 1: PROTEIN MELTING DOMAINS//THERMAL SHIFT ASSAYS//THERMOFLUOR

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
18607 478 38.5 70%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1035 9679 MOLTEN GLOBULE//APOMYOGLOBIN//PROTEIN FORMULATION

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 PROTEIN MELTING DOMAINS Author keyword 6 100% 1% 4
2 THERMAL SHIFT ASSAYS Author keyword 6 100% 1% 4
3 THERMOFLUOR Author keyword 3 32% 1% 7
4 DIFFERENTIAL TITRATION CALORIMETER Author keyword 2 67% 0% 2
5 ISOTHERMAL DENATURATION Author keyword 2 67% 0% 2
6 THERMAL SHIFT ANALYSIS Author keyword 2 67% 0% 2
7 CALORIMETRIC ENTHALPY Author keyword 2 50% 1% 3
8 IRREVERSIBLE THERMAL DENATURATION Author keyword 2 50% 1% 3
9 THERMODENATURATION Author keyword 2 33% 1% 4
10 THERMAL SHIFT ASSAY Author keyword 2 20% 1% 7

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class		 LCSH search Wikipedia search
1 PROTEIN MELTING DOMAINS 6 100% 1% 4 Search PROTEIN+MELTING+DOMAINS Search PROTEIN+MELTING+DOMAINS
2 THERMAL SHIFT ASSAYS 6 100% 1% 4 Search THERMAL+SHIFT+ASSAYS Search THERMAL+SHIFT+ASSAYS
3 THERMOFLUOR 3 32% 1% 7 Search THERMOFLUOR Search THERMOFLUOR
4 DIFFERENTIAL TITRATION CALORIMETER 2 67% 0% 2 Search DIFFERENTIAL+TITRATION+CALORIMETER Search DIFFERENTIAL+TITRATION+CALORIMETER
5 ISOTHERMAL DENATURATION 2 67% 0% 2 Search ISOTHERMAL+DENATURATION Search ISOTHERMAL+DENATURATION
6 THERMAL SHIFT ANALYSIS 2 67% 0% 2 Search THERMAL+SHIFT+ANALYSIS Search THERMAL+SHIFT+ANALYSIS
7 CALORIMETRIC ENTHALPY 2 50% 1% 3 Search CALORIMETRIC+ENTHALPY Search CALORIMETRIC+ENTHALPY
8 IRREVERSIBLE THERMAL DENATURATION 2 50% 1% 3 Search IRREVERSIBLE+THERMAL+DENATURATION Search IRREVERSIBLE+THERMAL+DENATURATION
9 THERMODENATURATION 2 33% 1% 4 Search THERMODENATURATION Search THERMODENATURATION
10 THERMAL SHIFT ASSAY 2 20% 1% 7 Search THERMAL+SHIFT+ASSAY Search THERMAL+SHIFT+ASSAY

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 THERMOFLUOR 10 57% 3% 12
2 OPTIMIZING EXPERIMENTAL PARAMETERS 9 83% 1% 5
3 SIGNIFICANT DISCREPANCIES 9 30% 5% 24
4 ENTROPY TITRATION 6 80% 1% 4
5 SHIFT ASSAYS 6 80% 1% 4
6 VANT HOFF 5 21% 5% 23
7 THERMAL SHIFT ASSAYS 4 22% 4% 18
8 STATISTICAL ERROR 4 31% 3% 12
9 CHEMICAL SYSTEM ENTROPY 4 67% 1% 4
10 GILL TITRATION CALORIMETER 4 75% 1% 3

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Theoretical aspects of isothermal titration calorimetry 1998 97 1 100%
Calorimetry and thermodynamics in drug design 2008 129 67 40%
Isothermal titration calorimetry: Experimental design, data analysis, and probing Macromolecule/Ligand binding and kinetic interactions 2008 109 20 45%
Optimization of protein purification and characterization using Thermofluor screens 2013 18 55 35%
Thermodynamic studies for drug design and screening 2012 15 47 49%
High throughput methods of assessing protein stability and aggregation 2009 47 28 46%
Isothermal titration calorimetry in membrane protein research 2014 5 108 18%
Thermal Denaturation Assays in Chemical Biology 2012 15 73 37%
Isothermal titration calorimetry and differential scanning calorimetry as complementary tools to investigate the energetics of biomolecular recognition 1999 381 109 22%
Recent developments in the use of differential scanning fluorometry in protein and small molecule discovery and characterization 2013 4 68 40%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 FENSKE 165 1 50% 0.4% 2
2 UCLA DOE STRUCT BIOL GENET 1 100% 0.4% 2
3 THERMODYNAM SOLUT POLYMERS 1 17% 1.0% 5
4 BIOCALORIMETRY 1 14% 1.0% 5
5 ARC COHERENT XRAY SCI 1 50% 0.2% 1
6 BIOSTRUCT BIOIMAGINES 1 50% 0.2% 1
7 DEV BRANCH FLOW ASSURANCE 1 50% 0.2% 1
8 BIOMOL DESIGN GRP 0 33% 0.2% 1
9 BIOPHYS ENZYMOL CHEM SCREENING SCI 0 33% 0.2% 1
10 DISCOVERY INNOVAT 0 33% 0.2% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000115758 NMR SCREENING//FRAGMENT BASED DRUG DISCOVERY//WATERLOGSY
2 0.0000107508 HUMAN HYALINE CARTILAGE//CONFORMATION OF MYOSIN//ISOPERIBOLIC BATCH CALORIMETRY
3 0.0000104949 PROTEIN SURFACTANT INTERACTION//VARIABLE ALPHA N PLUS BETA N//GRP BIOPHYS INTER ES
4 0.0000104033 PROTEIN FORMULATION//SUBVISIBLE PARTICLES//PROTEIN AGGREGATION
5 0.0000098540 DIPARTIMENTO SCI BIOL AMBIENTALI//CAVITY CREATION//WORK OF CAVITY CREATION
6 0.0000095288 STAPHYLOCOCCAL NUCLEASE//THERMODYNAMIC MOLECULAR SWITCH//PROTEIN THERMOSTABILITY
7 0.0000093450 THERMOKINETIC RESEARCH METHOD//CALORIMETRIC MODEL//TIME PARAMETER METHOD
8 0.0000087043 STREPTOMYCES SUBTILISIN INHIBITOR//DNASE INHIBITOR//M ECO RI
9 0.0000079301 AMORPHOUS CONTENT//ISOTHERMAL MICROCALORIMETRY//SORPTION CALORIMETRY
10 0.0000076254 PREFERENTIAL HYDRATION//PREFERENTIAL INTERACTIONS//PREFERENTIAL INTERACTION