Class information for:
Level 1: MPGES 1//PROSTAGLANDIN E SYNTHASE//MPGES 2

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
18805 469 42.5 90%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
670 12541 CYCLOOXYGENASE 2//COX 2//CYCLOOXYGENASE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MPGES 1 Author keyword 60 60% 14% 66
2 PROSTAGLANDIN E SYNTHASE Author keyword 15 44% 6% 27
3 MPGES 2 Author keyword 15 88% 1% 7
4 PGE SYNTHASE Author keyword 13 69% 2% 11
5 MICROSOMAL PROSTAGLANDIN E SYNTHASE 1 Author keyword 8 41% 3% 15
6 MICROSOMAL PROSTAGLANDIN E 2 SYNTHASE 1 Author keyword 7 57% 2% 8
7 CPGES Author keyword 6 80% 1% 4
8 MICROSOMAL PROSTAGLANDIN E SYNTHASE 1 MPGES 1 Author keyword 4 50% 1% 6
9 MICROSOMAL PROSTAGLANDIN E SYNTHASE Author keyword 3 43% 1% 6
10 MPGES 1 INHIBITORS Author keyword 3 100% 1% 3

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 MPGES 1 60 60% 14% 66 Search MPGES+1 Search MPGES+1
2 PROSTAGLANDIN E SYNTHASE 15 44% 6% 27 Search PROSTAGLANDIN+E+SYNTHASE Search PROSTAGLANDIN+E+SYNTHASE
3 MPGES 2 15 88% 1% 7 Search MPGES+2 Search MPGES+2
4 PGE SYNTHASE 13 69% 2% 11 Search PGE+SYNTHASE Search PGE+SYNTHASE
5 MICROSOMAL PROSTAGLANDIN E SYNTHASE 1 8 41% 3% 15 Search MICROSOMAL+PROSTAGLANDIN+E+SYNTHASE+1 Search MICROSOMAL+PROSTAGLANDIN+E+SYNTHASE+1
6 MICROSOMAL PROSTAGLANDIN E 2 SYNTHASE 1 7 57% 2% 8 Search MICROSOMAL+PROSTAGLANDIN+E+2+SYNTHASE+1 Search MICROSOMAL+PROSTAGLANDIN+E+2+SYNTHASE+1
7 CPGES 6 80% 1% 4 Search CPGES Search CPGES
8 MICROSOMAL PROSTAGLANDIN E SYNTHASE 1 MPGES 1 4 50% 1% 6 Search MICROSOMAL+PROSTAGLANDIN+E+SYNTHASE+1+MPGES+1 Search MICROSOMAL+PROSTAGLANDIN+E+SYNTHASE+1+MPGES+1
9 MICROSOMAL PROSTAGLANDIN E SYNTHASE 3 43% 1% 6 Search MICROSOMAL+PROSTAGLANDIN+E+SYNTHASE Search MICROSOMAL+PROSTAGLANDIN+E+SYNTHASE
10 MPGES 1 INHIBITORS 3 100% 1% 3 Search MPGES+1+INHIBITORS Search MPGES+1+INHIBITORS

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 E 2 SYNTHASE 55 63% 12% 55
2 E 2 BIOSYNTHESIS 37 52% 11% 50
3 MPGES 1 INHIBITORS 26 87% 3% 13
4 E 2 SYNTHASE 1 23 79% 3% 15
5 INDUCED PYRESIS 19 70% 3% 16
6 PROSTAGLANDIN E SYNTHASE 1 15 28% 10% 46
7 E ISOMERASE 15 88% 1% 7
8 H E ISOMERASE 15 88% 1% 7
9 MPGES 1 10 61% 2% 11
10 PROSTAGLANDIN E SYNTHASE 9 21% 8% 37

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Membrane prostaglandin E synthase-1: A novel therapeutic target 2007 224 183 46%
Characterization of Microsomal Prostaglandin E Synthase 1 Inhibitors 2014 6 60 75%
Identification and development of mPGES-1 inhibitors: where we are at? 2011 24 111 77%
Prostaglandin E synthases: Understanding their pathophysiological roles through mouse genetic models 2010 41 92 60%
Prostaglandin E-2 synthesis and secretion: The role of PGE(2) synthases 2006 189 84 35%
Multifaceted roles of PGE(2) in inflammation and cancer 2013 28 143 19%
mPGES-1 as a target for cancer suppression A comprehensive invited review "Phospholipase A(2) and lipid mediators" 2010 23 60 55%
Prostaglandin E synthase, a terminal enzyme for prostaglandin E-2 biosynthesis 2005 100 45 44%
Inhibitors of the Microsomal Prostaglandin E-2 Synthase-1 as Alternative to Non Steroidal Anti-Inflammatory Drugs (NSAIDs) - A Critical Review 2009 42 207 43%
Prostaglandin E synthase: A novel drug target for inflammation and cancer 2006 86 99 45%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 LIFF ZAFES 2 50% 0.6% 3
2 ANGIOL VASC BIOL INFLAMMAT 2 29% 1.1% 5
3 PHARMACEUT ANALYT 2 14% 2.1% 10
4 DEV INNOVAT MED NEEDS 1 33% 0.6% 3
5 PFIZER WORLDWIDE MED CHEM 1 30% 0.6% 3
6 BRIGHAM WOMENS HOSP RHEUMATOL IMMUNOL ALL 1 50% 0.2% 1
7 CELLULES TISSUS 1 50% 0.2% 1
8 CNS PAIN IMED 1 50% 0.2% 1
9 DRUG SAFETY TECHNOL 1 50% 0.2% 1
10 EXCELLENCE AGING MED 1 50% 0.2% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000207485 GEORGE M OBRIEN KIDNEY UROL DIS//GEORGE OBRIEN KIDNEY UROL DIS//SERV 151 E
2 0.0000195676 ONO 1301//IP RECEPTOR//EP4 RECEPTOR
3 0.0000188711 MICROSOMAL GLUTATHIONE TRANSFERASE//MGST1//MOL GENET PHARMACOL
4 0.0000159565 15 HYDROXYPROSTAGLANDIN DEHYDROGENASE//PROSTAGLANDIN TRANSPORTER//15 PGDH
5 0.0000158787 NEUROINFLAMMAT S//MOL NEUROSCI UNIT//BUTAPROST
6 0.0000148132 EXPT THER EUT PHARMACOINFORMAT//PROSTACYCLIN SYNTHASE GENE//PROSTACYCLIN SYNTHASE
7 0.0000109578 PROSTAGLANDIN H SYNTHASE//IMRECOXIB//AB HANCOCK JR MEM CANC
8 0.0000108386 CYCLOOXYGENASE 2//COX 2//CELECOXIB
9 0.0000091001 N ACETYL 4 AMINOPHENOL//FOETAL TESTIS//PROSTAGLANDIN E SERIES
10 0.0000090219 CRTH2//MOL BEHAV BIOL//PROSTAGLANDIN D 2