Class information for:
Level 1: CAMPTOTHECIN//SN 38//TOPOTECAN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
2077 2298 35.3 77%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2795 2580 CAMPTOTHECIN//SN 38//TOPOTECAN

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CAMPTOTHECIN Author keyword 148 32% 16% 379
2 SN 38 Author keyword 108 55% 6% 137
3 TOPOTECAN Author keyword 107 33% 12% 267
4 CPT 11 Author keyword 61 36% 6% 138
5 9 NITROCAMPTOTHECIN Author keyword 53 78% 2% 35
6 9 AMINOCAMPTOTHECIN Author keyword 47 79% 1% 30
7 HOMOCAMPTOTHECIN Author keyword 41 87% 1% 20
8 CAMPTOTHECINS Author keyword 40 57% 2% 47
9 IRINOTECAN Author keyword 36 13% 11% 248
10 TOPOISOMERASE I INHIBITORS Author keyword 22 49% 1% 33

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 CAMPTOTHECIN 148 32% 16% 379 Search CAMPTOTHECIN Search CAMPTOTHECIN
2 SN 38 108 55% 6% 137 Search SN+38 Search SN+38
3 TOPOTECAN 107 33% 12% 267 Search TOPOTECAN Search TOPOTECAN
4 CPT 11 61 36% 6% 138 Search CPT+11 Search CPT+11
5 9 NITROCAMPTOTHECIN 53 78% 2% 35 Search 9+NITROCAMPTOTHECIN Search 9+NITROCAMPTOTHECIN
6 9 AMINOCAMPTOTHECIN 47 79% 1% 30 Search 9+AMINOCAMPTOTHECIN Search 9+AMINOCAMPTOTHECIN
7 HOMOCAMPTOTHECIN 41 87% 1% 20 Search HOMOCAMPTOTHECIN Search HOMOCAMPTOTHECIN
8 CAMPTOTHECINS 40 57% 2% 47 Search CAMPTOTHECINS Search CAMPTOTHECINS
9 IRINOTECAN 36 13% 11% 248 Search IRINOTECAN Search IRINOTECAN
10 TOPOISOMERASE I INHIBITORS 22 49% 1% 33 Search TOPOISOMERASE+I+INHIBITORS Search TOPOISOMERASE+I+INHIBITORS

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 NSC 100880 188 78% 5% 124
2 CPT 11 166 39% 15% 337
3 CAMPTOTHECIN 163 26% 24% 552
4 DNA TOPOISOMERASE I 155 33% 17% 389
5 PLANT ANTITUMOR AGENTS 145 73% 5% 110
6 CARBOXYLATE FORMS 144 89% 3% 65
7 RING MODIFIED CAMPTOTHECIN 115 83% 3% 66
8 SN 38 101 53% 6% 133
9 20S CAMPTOTHECIN 99 88% 2% 46
10 CAMPTOTHECIN DERIVATIVE IRINOTECAN 99 78% 3% 66

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Cancer Therapies Utilizing the Camptothecins: A Review of the in Vivo Literature 2010 84 285 66%
Perspectives on Biologically Active Camptothecin Derivatives 2015 1 115 66%
Clinical pharmacokinetics and metabolism of irinotecan (CPT-11) 2001 339 132 67%
Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins 2002 271 155 71%
Camptothecin: current perspectives 2004 204 133 59%
Review Camptothecin: Current Perspectives 2006 98 94 71%
Towards new anticancer drugs: a decade of advances in synthesis of camptothecins and related alkaloids 2003 130 118 64%
Camptothecins - A review of their chemotherapeutic potential 2002 141 144 63%
Clinical applications of the camptothecins 1998 152 90 79%
Camptothecin and its analogues: a review on their chemotherapeutic potential 2005 44 67 75%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 STEHLIN FDN CANC 13 69% 0.5% 11
2 DANIEL DEN HOED KLIN 9 26% 1.3% 31
3 CAROLINA CANC NANOTECHOL EXCELLENCE 4 75% 0.1% 3
4 PEDIAT PHARMACOKINET THER EUT 3 17% 0.8% 18
5 GYNECOL ONCOL OUTREACH PROGRAM 3 100% 0.1% 3
6 JOINT GREEN CHEM 3 60% 0.1% 3
7 PROGRAM MOL THER EUT DRUG DISCOVERY 2 33% 0.3% 6
8 MED ON AB EXPT CHEMOTHER Y PHARMACOL 2 67% 0.1% 2
9 EXPT CHEMOTHER Y PHARMACOL 2 33% 0.2% 4
10 ROTTERDAM CANC 2 14% 0.4% 10

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000258602 NOTHAPODYTES FOETIDA//CAMPTOTHECA ACUMINATA//OPHIORRHIZA PUMILA
2 0.0000123116 TOPOISOMERASE II//ICRF 193//DNA TOPOISOMERASE II
3 0.0000071801 CARBOXYLESTERASE//DRUG METAB BIOPHARMACEUT//CARBOXYLESTERASES
4 0.0000069034 OXALIPLATIN//CAPECITABINE//IRINOTECAN
5 0.0000056244 PLATINUM RESISTANT//RECURRENT OVARIAN CANCER//PEGYLATED LIPOSOMAL DOXORUBICIN
6 0.0000052674 ABCG2//BCRP//BREAST CANCER RESISTANCE PROTEIN
7 0.0000044036 HPMA COPOLYMERS//HPMA COPOLYMER//POLYMER THER EUT
8 0.0000040739 LIPOSOMAL CISPLATIN//LIPOPLATIN//SPI 077
9 0.0000039405 VINORELBINE//GEMCITABINE//ADVANCED NON SMALL CELL LUNG CANCER
10 0.0000038972 BENZOCPHENANTHRIDINE//INDENOISOQUINOLINE//3 ARYLISOQUINOLINE