Class information for:
Level 1: FLAVONE ACETIC ACID//DMXAA//5 6 DIMETHYLXANTHENONE 4 ACETIC ACID

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
21065 374 32.2 78%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1318 8021 COMBRETASTATIN//STATHMIN//COMBRETASTATIN A 4

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FLAVONE ACETIC ACID Author keyword 61 86% 8% 31
2 DMXAA Author keyword 53 70% 12% 44
3 5 6 DIMETHYLXANTHENONE 4 ACETIC ACID Author keyword 19 80% 3% 12
4 FLAVONE 8 ACETIC ACID Author keyword 18 89% 2% 8
5 AUCKLAND CANC SOC Address 11 14% 21% 77
6 COLON 38 Author keyword 8 70% 2% 7
7 ANTIVASCULAR Author keyword 8 39% 4% 15
8 5 6 DIMETHYLXANTHENONE 4 ACETIC ACID DMXAA Author keyword 6 100% 1% 4
9 ASA404 Author keyword 6 50% 2% 8
10 ANTI VASCULAR AGENT Author keyword 2 67% 1% 2

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 FLAVONE ACETIC ACID 61 86% 8% 31 Search FLAVONE+ACETIC+ACID Search FLAVONE+ACETIC+ACID
2 DMXAA 53 70% 12% 44 Search DMXAA Search DMXAA
3 5 6 DIMETHYLXANTHENONE 4 ACETIC ACID 19 80% 3% 12 Search 5+6+DIMETHYLXANTHENONE+4+ACETIC+ACID Search 5+6+DIMETHYLXANTHENONE+4+ACETIC+ACID
4 FLAVONE 8 ACETIC ACID 18 89% 2% 8 Search FLAVONE+8+ACETIC+ACID Search FLAVONE+8+ACETIC+ACID
5 COLON 38 8 70% 2% 7 Search COLON+38 Search COLON+38
6 ANTIVASCULAR 8 39% 4% 15 Search ANTIVASCULAR Search ANTIVASCULAR
7 5 6 DIMETHYLXANTHENONE 4 ACETIC ACID DMXAA 6 100% 1% 4 Search 5+6+DIMETHYLXANTHENONE+4+ACETIC+ACID+DMXAA Search 5+6+DIMETHYLXANTHENONE+4+ACETIC+ACID+DMXAA
8 ASA404 6 50% 2% 8 Search ASA404 Search ASA404
9 ANTI VASCULAR AGENT 2 67% 1% 2 Search ANTI+VASCULAR+AGENT Search ANTI+VASCULAR+AGENT
10 AS1404 2 67% 1% 2 Search AS1404 Search AS1404

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 NSC 347512 192 98% 13% 49
2 FLAVONE 8 ACETIC ACID 181 88% 22% 84
3 FLAVONE ACETIC ACID 86 48% 35% 132
4 XANTHENONE 4 ACETIC ACID 73 96% 6% 23
5 COLON 38 TUMORS 52 100% 5% 18
6 ANTIVASCULAR AGENT 46 60% 13% 49
7 9 OXO 9H XANTHENE 4 ACETIC ACID 26 100% 3% 11
8 DMXAA 22 66% 6% 21
9 LM975 17 100% 2% 8
10 MURINE RENAL CANCER 13 48% 5% 20

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
FLAVONE ACETIC-ACID FROM LABORATORY TO CLINIC AND BACK 1993 37 50 84%
The potential of DMXAA (ASA404) in combination with docetaxel in advanced prostate cancer 2008 19 25 76%
Antivascular therapy of cancer: DMXAA 2003 100 70 44%
Immunomodulatory actions of xanthenone anticancer agents 1997 21 56 86%
Pharmacokinetic evaluation of vadimezan (ASA404, 5,6-dimethylxanthenone-4-acetic acid, DMXAA) 2011 2 45 80%
Preclinical Efficacy of Vascular Disrupting Agents in Non-Small-Cell Lung Cancer 2011 6 64 56%
Clinical Trials of Vascular Disrupting Agents in Advanced Non-Small-Cell Lung Cancer 2011 6 22 55%
FLAVONE 8-ACETIC ACID - OUR CURRENT UNDERSTANDING OF ITS MECHANISM OF ACTION IN SOLID TUMORS 1989 27 12 100%
METHODOLOGICAL ASPECTS OF PHASE-I STUDIES OF NOVEL ANTICANCER AGENTS (REVIEW) 1992 2 5 80%
Predicting pharmacokinetics and drug interactions in patients from in vitro and in vivo models: The experience with 5,6-dimethylxanthenone-4-acetic acid (DMXAA), an anti-cancer drug eliminated mainly by conjugation 2002 14 157 23%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 AUCKLAND CANC SOC 11 14% 21% 77
2 CANC CLIN PHARMACOL GRP 1 50% 0.5% 2
3 ARC 1016B 1 50% 0.3% 1
4 AUCKLAND CANC SOC MED SCI 1 50% 0.3% 1
5 BALTIMORE UMB 1 50% 0.3% 1
6 INSERM U640CNRS UMR 8151 1 50% 0.3% 1
7 INSERMCNRSUMR8151U640 1 50% 0.3% 1
8 MINIST AGR PL CHEM 1 50% 0.3% 1
9 PULMONOL KLIN 1 50% 0.3% 1
10 PRECLIN IMAGING IL 1 22% 0.5% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000281790 COMBRETASTATIN//COMBRETASTATIN A 4//COMBRETASTATINS
2 0.0000097444 2 STYRYLCHROMONES//3 STYRYLCHROMONES//AMINOFLAVONE
3 0.0000082705 BATRACYLIN//2 LITHIOMETHYLPHENYL ISOCYANIDE//4H 3 1 BENZOXAZINES
4 0.0000069482 ACYL GLUCURONIDES//ACYL GLUCURONIDE//ZOMEPIRAC
5 0.0000061494 1 4 ADDUCTS//BENZOFURAN 3 ONES//COPPER CATALYZED CASCADE ADDITION
6 0.0000047890 2 3 4 DIARYL 5 OXO 1 2 4 TRIAZINE 6 YLIDENEACETATES//3 4 DIARYL 1 2 4 TRIAZOLO 5 CARBOXYLATES//ADEUOVIRUS
7 0.0000047734 IMEXON//1 4 DIHYDRO 2 3 QUINOXALINEDIONE//CYANOAZIRIDINE
8 0.0000046137 CARBOGEN//TUMOR HYPOXIA//TUMOR OXYGENATION
9 0.0000045886 PYRANES//2 APYRIMIDINE//COLOR PHOTOGRAPH
10 0.0000045622 THALIDOMIDE//CC 5013//CC 4047