Class information for: |
Basic class information |
| ID | Publications | Average number of references |
Avg. shr. active ref. in WoS |
|---|---|---|---|
| 21966 | 342 | 36.5 | 71% |
Classes in level above (level 2) |
| ID, lev. above |
Publications | Label for level above |
|---|---|---|
| 395 | 16247 | CYTOCHROME P450//CYP2D6//PREGNANE X RECEPTOR |
Terms with highest relevance score |
| Rank | Term | Type of term | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
|---|---|---|---|---|---|---|
| 1 | LIVER SLICES | Author keyword | 13 | 35% | 9% | 31 |
| 2 | PRECISION CUT TISSUE SLICES | Author keyword | 13 | 80% | 2% | 8 |
| 3 | PRECISION CUT LIVER SLICES | Author keyword | 11 | 46% | 5% | 18 |
| 4 | RAT LIVER SLICES | Author keyword | 9 | 48% | 4% | 14 |
| 5 | PRECISION CUT SLICES | Author keyword | 7 | 67% | 2% | 6 |
| 6 | PRECISION CUT RAT LIVER SLICES | Author keyword | 4 | 67% | 1% | 4 |
| 7 | ETHOXYCOUMARIN O DEETHYLATION | Author keyword | 4 | 75% | 1% | 3 |
| 8 | LUNG SLICE CULTURE | Author keyword | 4 | 75% | 1% | 3 |
| 9 | LIVER SLICES PRECISION CUT | Author keyword | 3 | 100% | 1% | 3 |
| 10 | OPTIMAL SLICE VIABILITY | Author keyword | 3 | 100% | 1% | 3 |
Web of Science journal categories |
Author Key Words |
Key Words Plus |
| Rank | Web of Science journal category | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
|---|---|---|---|---|---|
| 1 | DYNAMIC ORGAN CULTURE | 75 | 71% | 18% | 60 |
| 2 | MULTIWELL PLATE CULTURE | 27 | 92% | 3% | 11 |
| 3 | PHARMACOTOXICOLOGY | 19 | 80% | 4% | 12 |
| 4 | BIOTRANSFORMATION ACTIVITY | 15 | 88% | 2% | 7 |
| 5 | RAT LIVER SLICES | 10 | 40% | 6% | 19 |
| 6 | TISSUE SLICES | 9 | 20% | 12% | 41 |
| 7 | KIDNEY SLICES | 9 | 50% | 4% | 13 |
| 8 | CYCLOSPORINE A METABOLISM | 9 | 59% | 3% | 10 |
| 9 | PRECISION CUT RAT | 6 | 47% | 3% | 9 |
| 10 | CUT TISSUE SLICES | 5 | 50% | 2% | 7 |
Journals |
Reviews |
| Title | Publ. year | Cit. | Active references | % act. ref. to same field |
|---|---|---|---|---|
| Preparation and culture of precision-cut organ slices from human and animal | 2013 | 9 | 30 | 53% |
| Development of a live tissue microtome: reflections of an amateur machinist | 2013 | 3 | 2 | 100% |
| Evaluation of the metabolism and hepatotoxicity of xenobiotics utilizing precision-cut slices | 2013 | 8 | 101 | 55% |
| Precision-cut liver slices: characteristics and use for in vitro pharmaco-toxicology | 2000 | 111 | 203 | 49% |
| Up-regulation of cytochrome P450 and phase II enzymes by xenobiotics in precision-cut tissue slices | 2013 | 5 | 73 | 62% |
| Precision-cut tissue slices as a tool to predict metabolism of novel drugs | 2007 | 20 | 174 | 55% |
| Cryopreservation of precision-cut tissue slices for application in drug metabolism research | 2003 | 19 | 85 | 73% |
| Precision-cut organ slices as a tool to study toxicity and metabolism of xenobiotics with special reference to non-hepatic tissues | 2002 | 39 | 187 | 37% |
| Past, present, and future applications of precision-cut liver slices for in vitro xenobiotic metabolism | 1996 | 62 | 96 | 45% |
| In vitro lung slices: a powerful approach for assessment of lung pathophysiology | 2010 | 19 | 46 | 41% |
Address terms |
| Rank | Address term | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
|---|---|---|---|---|---|
| 1 | PRECLIN DRUG VALIDAT UNIT | 2 | 67% | 0.6% | 2 |
| 2 | INSERM U295 | 1 | 40% | 0.6% | 2 |
| 3 | ABT ZELLBIOL TUMORBIOL | 1 | 50% | 0.3% | 1 |
| 4 | ORGANON S | 1 | 50% | 0.3% | 1 |
| 5 | SECUR MED | 1 | 50% | 0.3% | 1 |
| 6 | PMNT 7369 | 1 | 25% | 0.6% | 2 |
| 7 | PHARMACIA ITALIA SPA | 0 | 25% | 0.3% | 1 |
| 8 | EXPLANATORY TOXICOL | 0 | 13% | 0.6% | 2 |
| 9 | PHARMACEUT ANAL GRP | 0 | 20% | 0.3% | 1 |
| 10 | SECUR MEDICAMENT | 0 | 20% | 0.3% | 1 |
Related classes at same level (level 1) |
| Rank | Relatedness score | Related classes |
|---|---|---|
| 1 | 0.0000135215 | BIOARTIFICIAL LIVER//ARTIFICIAL LIVER//HYBRID ARTIFICIAL LIVER |
| 2 | 0.0000085061 | HEPATOCYTE TRANSPLANTATION//MARION BESSIN LIVER//LIVER REPOPULATION |
| 3 | 0.0000082633 | N N N TRIETHYLENEPHOSPHORAMIDE//THIOTEPA MERCAPTURATE//TEPA |
| 4 | 0.0000080875 | CYP2A6//CYP2A5//CYP2A13 |
| 5 | 0.0000078696 | INTERSPECIES SCALING//DMPK TRANSLAT SCI//WELL STIRRED MODEL |
| 6 | 0.0000074760 | CRYOBIOLOGY//INTRACELLULAR ICE FORMATION//CRYO-LETTERS |
| 7 | 0.0000072754 | ALDEHYDE OXIDASE//RS 8359//AOX1 |
| 8 | 0.0000068810 | PHARMACOKINET BIOANAL//CYP2D19//PROPRANOLOL ENANTIOMER |
| 9 | 0.0000067352 | ALPHA NAPHTHYLISOTHIOCYANATE//IDIOSYNCRATIC DRUG INDUCED LIVER INJURY//IDIOSYNCRATIC ADVERSE DRUG REACTIONS |
| 10 | 0.0000062681 | CYP3A//COCKTAIL//MECHANISM BASED INHIBITION |