Class information for:
Level 1: AGONIST AFFINITY//OPERATIONAL MODEL OF AGONISM//IRREVERSIBLE RECEPTOR INACTIVATION METHOD

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
22916 308 29.6 43%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
339 17217 CHLOROETHYLCLONIDINE//ALPHA1 ADRENOCEPTOR SUBTYPE//BETA3 ADRENOCEPTORS

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 AGONIST AFFINITY Author keyword 3 33% 2% 7
2 OPERATIONAL MODEL OF AGONISM Author keyword 2 38% 2% 5
3 IRREVERSIBLE RECEPTOR INACTIVATION METHOD Author keyword 1 100% 1% 2
4 FUNCTIONAL ANTAGONISM Author keyword 1 18% 2% 7
5 SPARE RECEPTOR Author keyword 1 29% 1% 4
6 MYOCARDIAL NOREPINEPHRINE Author keyword 1 40% 1% 2
7 ANALYTICAL PHARMACOLOGY Author keyword 1 50% 0% 1
8 CHENG PRUSOFF Author keyword 1 50% 0% 1
9 CHENG PRUSOFF EQUATION Author keyword 1 50% 0% 1
10 EFFICACY DISTRIBUTION Author keyword 1 50% 0% 1

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class		 LCSH search Wikipedia search
1 AGONIST AFFINITY 3 33% 2% 7 Search AGONIST+AFFINITY Search AGONIST+AFFINITY
2 OPERATIONAL MODEL OF AGONISM 2 38% 2% 5 Search OPERATIONAL+MODEL+OF+AGONISM Search OPERATIONAL+MODEL+OF+AGONISM
3 IRREVERSIBLE RECEPTOR INACTIVATION METHOD 1 100% 1% 2 Search IRREVERSIBLE+RECEPTOR+INACTIVATION+METHOD Search IRREVERSIBLE+RECEPTOR+INACTIVATION+METHOD
4 FUNCTIONAL ANTAGONISM 1 18% 2% 7 Search FUNCTIONAL+ANTAGONISM Search FUNCTIONAL+ANTAGONISM
5 SPARE RECEPTOR 1 29% 1% 4 Search SPARE+RECEPTOR Search SPARE+RECEPTOR
6 MYOCARDIAL NOREPINEPHRINE 1 40% 1% 2 Search MYOCARDIAL+NOREPINEPHRINE Search MYOCARDIAL+NOREPINEPHRINE
7 ANALYTICAL PHARMACOLOGY 1 50% 0% 1 Search ANALYTICAL+PHARMACOLOGY Search ANALYTICAL+PHARMACOLOGY
8 CHENG PRUSOFF 1 50% 0% 1 Search CHENG+PRUSOFF Search CHENG+PRUSOFF
9 CHENG PRUSOFF EQUATION 1 50% 0% 1 Search CHENG+PRUSOFF+EQUATION Search CHENG+PRUSOFF+EQUATION
10 EFFICACY DISTRIBUTION 1 50% 0% 1 Search EFFICACY+DISTRIBUTION Search EFFICACY+DISTRIBUTION

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 BINDING FREQUENCY 6 100% 1% 4
2 AGONIST DISSOCIATION CONSTANTS 3 57% 1% 4
3 PRUSOFF 3 60% 1% 3
4 OPERATIONAL MODEL 2 15% 3% 10
5 INDUCED SUPER SENSITIVITY 1 50% 1% 2
6 PHARMACOLOGICAL AGONISM 1 12% 3% 8
7 COMPLEX OCCUPANCY MECHANISMS 1 33% 1% 2
8 NULL METHOD 1 50% 0% 1
9 PHARMACOLOGICAL ESTIMATION 1 22% 1% 2
10 INHIBITION CURVES 0 20% 1% 2

Journals

Reviews


Title Publ. year Cit. Active
references		 % act. ref.
to same field
Assessing the (a)symmetry of concentration-effect curves: empirical versus mechanistic models 2002 51 29 28%
Why the Schild method is better than Schild realised 2007 15 12 42%
DEFINITION OF PHARMACOLOGICAL RECEPTORS 1992 105 40 25%
Assessing receptor affinity for inverse agonists: Schild and Cheng-Prusoff methods revisited 2007 11 26 31%
A personal view of pharmacology 1996 30 22 18%
Agonist binding, agonist affinity and agonist efficacy at G protein-coupled receptors 2008 33 57 14%
SCHILD REGRESSIONS AS INDICATORS OF NON-EQUILIBRIUM STEADY-STATES AND HETEROGENEOUS RECEPTOR POPULATIONS 1985 33 7 86%
Modeling of G-protein-coupled Receptor Signaling Pathways 2009 14 54 11%
RECEPTOR DISCRIMINATION AND CONTROL OF AGONIST-ANTAGONIST BINDING 1995 16 26 19%
International Union of Pharmacology. XIX. The IUPHAR receptor code: A proposal for an alphanumeric classification system 1998 15 42 10%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 GLENFIELD GEN HOSP MED ELDERLY 1 50% 0.3% 1
2 MED INTERNAL MED 1 11 SEIRYO MACHI 0 20% 0.3% 1
3 KATEDRA FIZJOL BIOCHEM FARMAKOL TOKSYKOL 0 17% 0.3% 1
4 CASILLA 2407 0 10% 0.3% 1
5 68 HALF MOON LANE 0 100% 0.3% 1
6 GRP BIOMAT REC 0 100% 0.3% 1
7 PHARMACOL ESCOLA PAULISTA MED 0 100% 0.3% 1
8 SAFETY PHARMACOL DRUG SAFETY EVALUAT 0 100% 0.3% 1
9 SELLY OAK HOSP MED ELDERLY 0 100% 0.3% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000124081 INTACT CELL BINDING//DIABET METAB DIS PROGRAM//GENE REPRESSOR
2 0.0000119386 POSTJUNCTIONAL ALPHA 2 ADRENOCEPTORS//UK14304//ALPHA 1 ADRENOCEPTORS
3 0.0000117838 T 0509//ZINTEROL//BETA ADRENERGIC RECEPTOR SUBTYPE
4 0.0000111325 AGONIST ANTAGONIST DISCRIMINATION//BINDING THERMODYNAMICS//W SSM RATS
5 0.0000104856 CAS 76963 41 2//MIFENTIDINE//HISTAMINE H 2 RECEPTORS
6 0.0000102898 RHYTHMICAL CONTRACTIONS//SEROTONIN2A RECEPTORS//MOTILITY ANALYSIS
7 0.0000097183 XAMOTEROL//EPANOLOL//DENOPAMINE
8 0.0000095581 GTP REGULATORY PROTEINS//INOSITOL TRISPHOSPHATE PHOSPHATASE//POSITIVE INOTROPIC EFFECT
9 0.0000094144 TRANS MEMBRANE CONDUCTANCE//ONSAGER RECIPROCITY THEOREM//INSTANTANEOUS RATE
10 0.0000090952 ALPHA BETA ADRENOCEPTOR BLOCKADE//KMUP 1//EUGENOSEDIN A