Class information for:
Level 1: FARNESYLTRANSFERASE//FARNESYL TRANSFERASE INHIBITOR//FARNESYL TRANSFERASE INHIBITORS

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
2467 2168 43.7 86%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1710 6112 FARNESYLTRANSFERASE//PALMITOYLATION//RLIP76

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FARNESYLTRANSFERASE Author keyword 98 67% 4% 87
2 FARNESYL TRANSFERASE INHIBITOR Author keyword 62 55% 4% 77
3 FARNESYL TRANSFERASE INHIBITORS Author keyword 52 56% 3% 63
4 PROTEIN FARNESYLTRANSFERASE Author keyword 40 79% 1% 26
5 TIPIFARNIB Author keyword 30 60% 2% 33
6 LONAFARNIB Author keyword 30 68% 1% 26
7 R115777 Author keyword 30 84% 1% 16
8 PROTEIN PRENYLATION Author keyword 28 47% 2% 44
9 FARNESYL PROTEIN TRANSFERASE Author keyword 26 67% 1% 24
10 PRENYLATION Author keyword 23 26% 4% 78

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 FARNESYLTRANSFERASE 98 67% 4% 87 Search FARNESYLTRANSFERASE Search FARNESYLTRANSFERASE
2 FARNESYL TRANSFERASE INHIBITOR 62 55% 4% 77 Search FARNESYL+TRANSFERASE+INHIBITOR Search FARNESYL+TRANSFERASE+INHIBITOR
3 FARNESYL TRANSFERASE INHIBITORS 52 56% 3% 63 Search FARNESYL+TRANSFERASE+INHIBITORS Search FARNESYL+TRANSFERASE+INHIBITORS
4 PROTEIN FARNESYLTRANSFERASE 40 79% 1% 26 Search PROTEIN+FARNESYLTRANSFERASE Search PROTEIN+FARNESYLTRANSFERASE
5 TIPIFARNIB 30 60% 2% 33 Search TIPIFARNIB Search TIPIFARNIB
6 LONAFARNIB 30 68% 1% 26 Search LONAFARNIB Search LONAFARNIB
7 R115777 30 84% 1% 16 Search R115777 Search R115777
8 PROTEIN PRENYLATION 28 47% 2% 44 Search PROTEIN+PRENYLATION Search PROTEIN+PRENYLATION
9 FARNESYL PROTEIN TRANSFERASE 26 67% 1% 24 Search FARNESYL+PROTEIN+TRANSFERASE Search FARNESYL+PROTEIN+TRANSFERASE
10 PRENYLATION 23 26% 4% 78 Search PRENYLATION Search PRENYLATION

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FARNESYLTRANSFERASE 274 63% 13% 279
2 FARNESYL 238 76% 8% 167
3 FARNESYL TRANSFERASE INHIBITORS 218 49% 15% 326
4 PRENYLATION 184 50% 12% 266
5 FARNESYL PROTEIN TRANSFERASE 166 56% 9% 204
6 TETRAPEPTIDE INHIBITORS 130 95% 2% 42
7 PROTEIN TRANSFERASE 121 67% 5% 110
8 GERANYLGERANYLTRANSFERASE TYPE I 117 93% 2% 43
9 GERANYLGERANYLTRANSFERASE I 102 75% 3% 73
10 RAS FARNESYLATION 87 81% 2% 52

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Protein prenylation: Molecular mechanisms and functional consequences 1996 1256 200 71%
Protein Prenylation: Enzymes, Therapeutics, and Biotechnology Applications 2015 3 114 77%
Targeting protein prenylation for cancer therapy 2011 111 214 63%
Protein prenyltransferases 1996 504 75 79%
Farnesyl transferase inhibitors 2006 183 209 60%
Farnesyltransferase inhibitors: A detailed chemical view on an elusive biological problem 2008 64 225 85%
Structural biology of protein farnesyltransferase and geranylgeranyltransferase type I 2006 115 171 78%
Ras protein farnesyltransferase: A strategic target for anticancer therapeutic development 1999 363 146 49%
Farnesyltransferase and geranylgeranyltransferase I: structures, mechanism, inhibitors and molecular modeling 2015 1 78 77%
FARNESYLTRANSFERASE INHIBITORS - RAS RESEARCH YIELDS A POTENTIAL CANCER THERAPEUTIC 1994 434 22 77%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 KENTUCKY STRUCT BIOL 12 52% 0.7% 16
2 ANTICANC PROGRAM 3 100% 0.1% 3
3 ABT CHEM BIOL 3 13% 1.1% 23
4 GLENOLDEN 2 23% 0.4% 9
5 PROGRAM CANC STEM CELL BIOL 2 18% 0.6% 12
6 PROGRAM PROTEASES 2 67% 0.1% 2
7 EA GRIIOT 4481 2 21% 0.3% 7
8 LUTTE CONTRE CANC CLAUDIUS REGAUD 1 100% 0.1% 2
9 INNOVAT THER EUT ONCOL MOL 1 18% 0.3% 7
10 BIOCHEM MOL SCI 1 22% 0.2% 5

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000129830 FARNESYLTHIOSALICYLIC ACID//SALIRASIB//ABT STRUKTURELLE BIOL
2 0.0000109389 BIOMARKERS BRANCH//CLONOGEN//COLORADO PARTY
3 0.0000093311 CARA INCHADA//MED VET D SA//COMPETITION CAPACITY
4 0.0000079427 LOVASTATIN//BB BIOCYT//PEDIAT PNEUMONOL ALLERG DIS HEMATOL
5 0.0000078933 PHOSDUCIN//PHOSDUCIN LIKE PROTEIN//PHOSDUCIN LIKE PROTEINS
6 0.0000078320 PERILLYL ALCOHOL//DIETARY ISOPRENOIDS//APOMINE
7 0.0000071092 RAB25//RAB//RAB PROTEINS
8 0.0000068235 N MYRISTOYLTRANSFERASE//PALMITOYLATION//PROTEIN N MYRISTOYLATION
9 0.0000066472 CHOROIDEREMIA//POU3F4//DFN3
10 0.0000062825 SQUALENE SYNTHASE//ZARAGOZIC ACIDS//SQUALENE SYNTHASE INHIBITOR