Class information for:
Level 1: EGF POLYMORPHISM//GEFITINIB THERAPY//INTRON 1 POLYMORPHISM

Basic class information

ID Publications Average number
of references
Avg. shr. active
ref. in WoS
25024 245 36.3 89%



Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)



ID, lev.
above
Publications Label for level above
451 15419 HER 2//TRASTUZUMAB//LAPATINIB

Terms with highest relevance score



Rank Term Type of term Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ.
in class
1 EGF POLYMORPHISM Author keyword 3 100% 1% 3
2 GEFITINIB THERAPY Author keyword 1 100% 1% 2
3 INTRON 1 POLYMORPHISM Author keyword 1 100% 1% 2
4 MOL ONCOL CI Address 1 50% 1% 2
5 AC REPEAT Author keyword 1 50% 0% 1
6 AVERAGE GENE COPY NUMBER Author keyword 1 50% 0% 1
7 BIOINFORMAT SIGNALLING UNIT Address 1 50% 0% 1
8 GC BOX BINDING FACTOR Author keyword 1 50% 0% 1
9 GENET TRANSLAT MED PREVENT Address 1 50% 0% 1
10 GRP ONCOL MOL Address 1 50% 0% 1

Web of Science journal categories

Author Key Words



Rank Web of Science journal category Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ.
in class
LCSH search Wikipedia search
1 EGF POLYMORPHISM 3 100% 1% 3 Search EGF+POLYMORPHISM Search EGF+POLYMORPHISM
2 GEFITINIB THERAPY 1 100% 1% 2 Search GEFITINIB+THERAPY Search GEFITINIB+THERAPY
3 INTRON 1 POLYMORPHISM 1 100% 1% 2 Search INTRON+1+POLYMORPHISM Search INTRON+1+POLYMORPHISM
4 AC REPEAT 1 50% 0% 1 Search AC+REPEAT Search AC+REPEAT
5 AVERAGE GENE COPY NUMBER 1 50% 0% 1 Search AVERAGE+GENE+COPY+NUMBER Search AVERAGE+GENE+COPY+NUMBER
6 GC BOX BINDING FACTOR 1 50% 0% 1 Search GC+BOX+BINDING+FACTOR Search GC+BOX+BINDING+FACTOR
7 LINKER SCANNING 1 50% 0% 1 Search LINKER+SCANNING Search LINKER+SCANNING
8 PLASMA EGF 1 50% 0% 1 Search PLASMA+EGF Search PLASMA+EGF
9 PROGNOSTIC ESTIMATES 1 50% 0% 1 Search PROGNOSTIC+ESTIMATES Search PROGNOSTIC+ESTIMATES
10 R497K 1 50% 0% 1 Search R497K Search R497K

Key Words Plus



Rank Web of Science journal category Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 EGF GENE 35 72% 11% 28
2 SP1 RECOGNITION SITE 8 75% 2% 6
3 INTRON 1 POLYMORPHISM 8 46% 5% 13
4 61 G A 8 100% 2% 5
5 5UTR VARIANT A61G 6 100% 2% 4
6 A61G POLYMORPHISM 6 100% 2% 4
7 POLYMORPHIC SEQUENCE 6 100% 2% 4
8 INTRON 1 5 19% 9% 22
9 R497K POLYMORPHISM 4 75% 1% 3
10 EGFR GENE 4 25% 5% 13

Journals

Reviews



Title Publ. year Cit. Active
references
% act. ref.
to same field
EGF +61A > G polymorphism and gastrointestinal cancer risk: A HuGE review and meta-analysis 2013 7 30 43%
EGF receptor-targeted therapy in non-small-cell lung cancer: role of germline polymorphisms in outcome and toxicity 2012 7 75 25%
Polymorphisms to Predict Outcome to the Tyrosine Kinase Inhibitors Gefitinib, Erlotinib, Sorafenib and Sunitinib 2012 4 58 29%
Association of epidermal growth factor receptor (EGFR) gene polymorphism with lung cancer risk: a systematic review 2014 0 12 42%
Pharmacogenetics of small-molecule tyrosine kinase inhibitors: Optimizing the magic bullet 2010 5 42 24%
Lack of association between EGF+61A > G polymorphism and melanoma susceptibility in Caucasians: A HuGE review and meta-analysis 2013 0 20 30%
Modulation of EGFR gene transcription by secondary structures, a polymorphic repetitive sequence and mutations - a link between genetics and epigenetics 2000 39 74 23%
Clinical Pharmacogenetics in Oncology: the Paradigm of Molecular Targeted Therapies 2010 5 84 12%
Promises and pitfalls in the prediction of antiepidermal growth factor receptor activity 2005 0 44 16%
INVITRO TRANSCRIPTION OF EPIDERMAL GROWTH-FACTOR RECEPTOR GENE 1991 1 15 33%

Address terms



Rank Address term Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ.
in class
1 MOL ONCOL CI 1 50% 0.8% 2
2 BIOINFORMAT SIGNALLING UNIT 1 50% 0.4% 1
3 GENET TRANSLAT MED PREVENT 1 50% 0.4% 1
4 GRP ONCOL MOL 1 50% 0.4% 1
5 HEBEI GEN HOSP 1 50% 0.4% 1
6 HOSP UNIV SAO PAULO 1 50% 0.4% 1
7 MA MIGLIAVACCA LIVER DIS 1 50% 0.4% 1
8 PSYCHIAT PEDIAT HUMAN GENET 1 50% 0.4% 1
9 SPORE LUNG CANC 1 50% 0.4% 1
10 SERV ENDOSCOPIAS 0 33% 0.4% 1

Related classes at same level (level 1)



Rank Relatedness score Related classes
1 0.0000179701 BREAST CARCINOMA CELL LINE//BIOTINYLATED EPIDERMAL GROWTH FACTOR//BREAST CANCER BIOPSIES
2 0.0000130599 NIMOTUZUMAB//H R3//CETUXIMAB
3 0.0000128380 VEGF POLYMORPHISMS//VEGF POLYMORPHISM//RS2010963
4 0.0000126617 FLIGHTLESS I//TTYH1//TWEETY
5 0.0000118127 GEFITINIB//ERLOTINIB//EGFR MUTATION
6 0.0000112728 IMMUNOGENE//MED MOLEC BIOL SHINJUKU KU//ERBB PROTEINS
7 0.0000111974 FAMILIAL GLIOMA//RTEL1//EVANSTON KELLOGG CANC CARE
8 0.0000110624 HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2//ADVANCED METASTATIC DISEASE//ANTI EGF RECEPTOR ANTIBODY
9 0.0000083185 PAPER CAPILLARY PERMEATION ADSORPTION//SEPARATABILITY//APRC
10 0.0000079951 ASTROGLIAL CELL CULTURES//NEUROSTATIN//ERBB1