Class information for:
Level 1: 5 LIPOXYGENASE//LEUKOTRIENE A4 HYDROLASE//5 LIPOXYGENASE ACTIVATING PROTEIN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
2589 2127 39.1 85%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
860 10928 5 LIPOXYGENASE//EXPT THER EUT REPERFUS INJURY//LEUKOTRIENES

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 5 LIPOXYGENASE Author keyword 133 37% 13% 283
2 LEUKOTRIENE A4 HYDROLASE Author keyword 61 76% 2% 42
3 5 LIPOXYGENASE ACTIVATING PROTEIN Author keyword 59 71% 2% 48
4 BLT2 Author keyword 53 89% 1% 24
5 LEUKOTRIENE Author keyword 39 22% 7% 157
6 LEUKOTRIENES Author keyword 24 14% 7% 155
7 5 LIPOXYGENASE ACTIVATING PROTEIN FLAP Author keyword 23 100% 0% 10
8 CHEM 2 Address 21 36% 2% 48
9 LEUKOTRIENE A4 Author keyword 21 75% 1% 15
10 ALOX5AP Author keyword 20 66% 1% 19

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 5 LIPOXYGENASE 133 37% 13% 283 Search 5+LIPOXYGENASE Search 5+LIPOXYGENASE
2 LEUKOTRIENE A4 HYDROLASE 61 76% 2% 42 Search LEUKOTRIENE+A4+HYDROLASE Search LEUKOTRIENE+A4+HYDROLASE
3 5 LIPOXYGENASE ACTIVATING PROTEIN 59 71% 2% 48 Search 5+LIPOXYGENASE+ACTIVATING+PROTEIN Search 5+LIPOXYGENASE+ACTIVATING+PROTEIN
4 BLT2 53 89% 1% 24 Search BLT2 Search BLT2
5 LEUKOTRIENE 39 22% 7% 157 Search LEUKOTRIENE Search LEUKOTRIENE
6 LEUKOTRIENES 24 14% 7% 155 Search LEUKOTRIENES Search LEUKOTRIENES
7 5 LIPOXYGENASE ACTIVATING PROTEIN FLAP 23 100% 0% 10 Search 5+LIPOXYGENASE+ACTIVATING+PROTEIN+FLAP Search 5+LIPOXYGENASE+ACTIVATING+PROTEIN+FLAP
8 LEUKOTRIENE A4 21 75% 1% 15 Search LEUKOTRIENE+A4 Search LEUKOTRIENE+A4
9 ALOX5AP 20 66% 1% 19 Search ALOX5AP Search ALOX5AP
10 LEUKOTRIENE B 4 19 19% 4% 88 Search LEUKOTRIENE+B+4 Search LEUKOTRIENE+B+4

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 LEUKOTRIENE SYNTHESIS 74 48% 5% 113
2 A4 HYDROLASE 73 88% 2% 35
3 5 LIPOXYGENASE ACTIVATING PROTEIN 65 45% 5% 108
4 LTA4 HYDROLASE 59 90% 1% 26
5 ARACHIDONATE 5 LIPOXYGENASE 45 54% 3% 58
6 B 4 45 54% 3% 57
7 B 4 RECEPTOR 38 60% 2% 42
8 5 LIPOXYGENASE 35 15% 10% 215
9 LEUKOTRIENE BIOSYNTHESIS INHIBITOR 30 62% 1% 31
10 LEUKOTRIENE B 4 RECEPTOR 29 43% 2% 50

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease 2015 4 104 71%
Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease 2011 126 441 51%
Mechanisms of disease: Leukotrienes 2007 411 116 37%
What's all the FLAP about?: 5-lipoxygenase-activating protein inhibitors for inflammatory diseases 2008 92 53 79%
Targeting leukotriene B-4 in inflammation 2014 7 118 75%
Recent Advances in the Search for Novel 5-Lipoxygenase Inhibitors 2014 9 43 56%
5-Lipoxygenase: regulation of expression and enzyme activity 2007 138 91 75%
The role of leukotrienes in allergic diseases 2015 2 194 31%
Prostaglandins and leukotrienes: Advances in eicosanoid biology 2001 1694 55 18%
5-Lipoxygenase inhibitors: a review of recent developments and patents 2010 47 106 64%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CHEM 2 21 36% 2.3% 48
2 PHYSIOL CHEM 2 11 19% 2.4% 50
3 PHARMACEUT ANALYT 6 27% 0.9% 19
4 PHARMACEUT CHEM ZAFES 6 43% 0.5% 10
5 CHAIR PHARMACEUT MED CHEM 5 30% 0.7% 14
6 CARDIOPULM PHARMACOL 3 28% 0.4% 9
7 ZAFES CMP 2 38% 0.2% 5
8 ARRHENIUS S A4 2 67% 0.1% 2
9 CARDIOVASC P PHARMACEUT DEV 2 67% 0.1% 2
10 LUMINAL GASTROENTEROL 2 67% 0.1% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000204264 5 OXO ETE//CLAUDE PEPPER//5 HETE
2 0.0000180748 PRANLUKAST//MONTELUKAST//CYSTEINYL LEUKOTRIENES
3 0.0000156183 12 LIPOXYGENASE//15 LIPOXYGENASE//15 LIPOXYGENASE 1
4 0.0000109452 TMEM132A//C FOS SERUM RESPONSE ELEMENT//FAS FASL INTERACTIONS
5 0.0000104808 EXPT THER EUT REPERFUS INJURY//RESOLVINS//LIPOXINS
6 0.0000086752 TENIDAP//TEPOXALIN//TENIDAP SODIUM
7 0.0000086009 GROWTH FACTOR DEPRIVATION THERAPY//A63162//MED DISCOVERY
8 0.0000080627 MEMORY AND LEARNING IMPAIRMENT//ALZHEIMER KOR KUTATOCSOPORT//FLAP PROTEIN
9 0.0000080495 MPGES 1//PROSTAGLANDIN E SYNTHASE//MPGES 2
10 0.0000075897 LIPOPHILIC MOIETY//3 HEXENOL//BIOCARTOL