Class information for:
Level 1: MOL INNOVAT DRUG DISCOVERY//N HYDROXYGUANIDINES//LERNER FDN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
2602 2123 42.8 87%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
370 16580 NITRIC OXIDE//PEROXYNITRITE//NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MOL INNOVAT DRUG DISCOVERY Address 13 26% 2% 42
2 N HYDROXYGUANIDINES Author keyword 12 86% 0% 6
3 LERNER FDN Address 9 83% 0% 5
4 HEME REDUCTION Author keyword 8 70% 0% 7
5 SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS Author keyword 8 100% 0% 5
6 CARDIOVASC MEDDAVIS HEART LUNG Address 6 80% 0% 4
7 IMMUNOL NB3 Address 6 100% 0% 4
8 N OMEGA HYDROXY L ARGININE Author keyword 5 60% 0% 6
9 LOW FREQUENCY EPR IN VIVO PHYSIOL Address 5 63% 0% 5
10 MED MED MED HEMATOL ONCOL Address 5 63% 0% 5

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class		 LCSH search Wikipedia search
1 N HYDROXYGUANIDINES 12 86% 0% 6 Search N+HYDROXYGUANIDINES Search N+HYDROXYGUANIDINES
2 HEME REDUCTION 8 70% 0% 7 Search HEME+REDUCTION Search HEME+REDUCTION
3 SELECTIVE NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS 8 100% 0% 5 Search SELECTIVE+NEURONAL+NITRIC+OXIDE+SYNTHASE+INHIBITORS Search SELECTIVE+NEURONAL+NITRIC+OXIDE+SYNTHASE+INHIBITORS
4 N OMEGA HYDROXY L ARGININE 5 60% 0% 6 Search N+OMEGA+HYDROXY+L+ARGININE Search N+OMEGA+HYDROXY+L+ARGININE
5 N G HYDROXY L ARGININE 5 55% 0% 6 Search N+G+HYDROXY+L+ARGININE Search N+G+HYDROXY+L+ARGININE
6 HYDROXYGUANIDINE 4 56% 0% 5 Search HYDROXYGUANIDINE Search HYDROXYGUANIDINE
7 FORMAMIDOXIME 3 100% 0% 3 Search FORMAMIDOXIME Search FORMAMIDOXIME
8 HEME FMN ELECTRON TRANSFER 3 100% 0% 3 Search HEME+FMN+ELECTRON+TRANSFER Search HEME+FMN+ELECTRON+TRANSFER
9 INTRAPROTEIN KINETICS 3 100% 0% 3 Search INTRAPROTEIN+KINETICS Search INTRAPROTEIN+KINETICS
10 NG HYDROXY L ARGININE 3 100% 0% 3 Search NG+HYDROXY+L+ARGININE Search NG+HYDROXY+L+ARGININE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 OXYGENASE DOMAIN 212 92% 4% 83
2 SUBUNIT DIMERIZATION 107 93% 2% 40
3 OXYGENASE DIMER 92 92% 2% 36
4 HYDROXY L ARGININE 89 47% 7% 142
5 MACROPHAGE NO SYNTHASE 87 88% 2% 42
6 REDUCTASE DOMAIN 71 74% 2% 53
7 TETRAHYDROBIOPTERIN BINDING 65 95% 1% 21
8 PTERIN 65 60% 3% 70
9 2 DOMAIN CONSTRUCT 60 100% 1% 20
10 BIDOMAIN STRUCTURE 57 95% 1% 19

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Nitric oxide synthases: structure, function and inhibition 2001 2008 210 56%
Mammalian nitric oxide synthases 1999 549 124 76%
Nitric oxide and macrophage function 1997 2385 170 31%
Structure-function studies on nitric oxide synthases 2005 153 113 83%
NO synthase: Structures and mechanisms 2010 89 125 74%
Nitric oxide synthases: regulation and function 2012 305 166 16%
Tetrahydrobiopterin in nitric oxide synthase 2013 13 53 92%
Update on mechanism and catalytic regulation in the NO synthases 2004 259 45 62%
NITRIC OXIDES SYNTHASES - PROPERTIES AND CATALYTIC MECHANISM 1995 919 131 61%
Development of nitric oxide synthase inhibitors for neurodegeneration and neuropathic pain 2014 8 234 61%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MOL INNOVAT DRUG DISCOVERY 13 26% 2.0% 42
2 LERNER FDN 9 83% 0.2% 5
3 CARDIOVASC MEDDAVIS HEART LUNG 6 80% 0.2% 4
4 IMMUNOL NB3 6 100% 0.2% 4
5 LOW FREQUENCY EPR IN VIVO PHYSIOL 5 63% 0.2% 5
6 MED MED MED HEMATOL ONCOL 5 63% 0.2% 5
7 TECHNOPORT 4 75% 0.1% 3
8 CHEM LIFE PROC 4 10% 1.8% 38
9 LSOD 3 100% 0.1% 3
10 DRUG DISCOVERY CHEM BIOL 3 19% 0.8% 16

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000165792 VASCULAR ENDOTHELIAL DYSFUNCTION//MOL CARDIOBIOL PROGRAM//VASCULAR ENDOTHELIUM DYSFUNCTION
2 0.0000156958 TYPE I INTERLEUKIN 1 RECEPTOR//INOS PROMOTER//ORG SCI TECHNOL
3 0.0000132461 ARTIF ORGANS TRANSPLANTAT GENE THER Y//CHEM TECH INC//CHRONIC RENAL TRANSPLANT FAILURE
4 0.0000131796 AMINOETHYL ISOTHIOUREA//VASCULAR HYPOREACTIVITY//N G METHYL L ARGININE HYDROCHLORIDE
5 0.0000121278 ZENTRUM PHARMAKOL//URINARY NITRITE NITRATE//AIDS PATHOGENESIS MOL THER EUT
6 0.0000113079 COLLAGENOUS PROTEIN BIOSYNTHESIS//NOS3//IMMUNOL IMMUNOTHER IE CANC
7 0.0000101064 NADPH DIAPHORASE//7 NITROINDAZOLE//NEURONAL NITRIC OXIDE SYNTHASE
8 0.0000100593 GRP IMMUNOBIOL//HUMAN NUTR METAB DIS LIM 25//EXPT ONCOL LIM 24
9 0.0000093527 AGR REPROD PHYSIOL//CATTEDRA A//IST FISIOL VET
10 0.0000076438 NITRIC OXIDE SYNTHASE I//NOS I//CENT ULTRASTRUCT TEAM