Class information for:
Level 1: SIROLIMUS//EVEROLIMUS//PROLIFERATION SIGNAL INHIBITORS

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
2898 2042 31.5 86%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
126 23061 TRANSPLANTATION//TRANSPLANTATION PROCEEDINGS//MYCOPHENOLIC ACID

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 SIROLIMUS Author keyword 200 34% 23% 477
2 EVEROLIMUS Author keyword 62 23% 12% 244
3 PROLIFERATION SIGNAL INHIBITORS Author keyword 52 87% 1% 26
4 CERTICAN Author keyword 33 100% 1% 13
5 SDZ RAD Author keyword 26 87% 1% 13
6 CALCINEURIN INHIBITORS Author keyword 21 16% 6% 116
7 BELATACEPT Author keyword 19 43% 2% 34
8 IMMUNOL ORGAN TRANSPLANTAT Address 17 26% 3% 54
9 CALCINEURIN INHIBITOR WITHDRAWAL Author keyword 9 83% 0% 5
10 CHRONIC ALLOGRAFT NEPHROPATHY Author keyword 8 15% 2% 49

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 SIROLIMUS 200 34% 23% 477 Search SIROLIMUS Search SIROLIMUS
2 EVEROLIMUS 62 23% 12% 244 Search EVEROLIMUS Search EVEROLIMUS
3 PROLIFERATION SIGNAL INHIBITORS 52 87% 1% 26 Search PROLIFERATION+SIGNAL+INHIBITORS Search PROLIFERATION+SIGNAL+INHIBITORS
4 CERTICAN 33 100% 1% 13 Search CERTICAN Search CERTICAN
5 SDZ RAD 26 87% 1% 13 Search SDZ+RAD Search SDZ+RAD
6 CALCINEURIN INHIBITORS 21 16% 6% 116 Search CALCINEURIN+INHIBITORS Search CALCINEURIN+INHIBITORS
7 BELATACEPT 19 43% 2% 34 Search BELATACEPT Search BELATACEPT
8 CALCINEURIN INHIBITOR WITHDRAWAL 9 83% 0% 5 Search CALCINEURIN+INHIBITOR+WITHDRAWAL Search CALCINEURIN+INHIBITOR+WITHDRAWAL
9 CHRONIC ALLOGRAFT NEPHROPATHY 8 15% 2% 49 Search CHRONIC+ALLOGRAFT+NEPHROPATHY Search CHRONIC+ALLOGRAFT+NEPHROPATHY
10 CYCLOSPORINE WITHDRAWAL 4 67% 0% 4 Search CYCLOSPORINE+WITHDRAWAL Search CYCLOSPORINE+WITHDRAWAL

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 EARLY CYCLOSPORINE WITHDRAWAL 157 69% 7% 133
2 SDZ RAD 133 63% 7% 133
3 SIROLIMUS 88 21% 19% 381
4 CALCINEURIN INHIBITORS 83 26% 14% 282
5 RAPAMYCIN 57 11% 23% 477
6 MYCOPHENOLATE MOFETIL 50 11% 22% 443
7 REDUCED EXPOSURE CYCLOSPORINE 50 86% 1% 25
8 IMMUNOSUPPRESSANT SDZ RAD 47 88% 1% 22
9 CERTICAN 42 94% 1% 15
10 SIROLIMUS BASED THERAPY 34 65% 2% 32

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Target of rapamycin inhibitors (Sirolimus and Everolimus) for primary immunosuppression of kidney transplant recipients: A systematic review and meta-analysis of randomized trials 2006 179 36 72%
Calcineurin inhibitor-sparing regimens in solid organ transplantation: focus on improving renal function and nephrotoxicity 2008 174 110 45%
Calcineurin inhibitor-sparing regimens based on mycophenolic acid after kidney transplantation 2015 1 38 63%
mTOR inhibition: A promising strategy for stabilization of atherosclerotic plaques 2014 13 65 35%
Focus on mTOR inhibitors and tacrolimus in renal transplantation: Pharmacokinetics, exposure-response relationships, and clinical outcomes 2014 4 53 87%
Immunosuppressive minimization with mTOR inhibitors and belatacept 2015 1 37 46%
A Comprehensive Review of Everolimus Clinical Reports: A New Mammalian Target of Rapamycin Inhibitor 2012 23 46 80%
Use of sirolimus in solid organ transplantation 2007 95 154 69%
Review of combination therapy with mTOR inhibitors and tacrolimus minimization after transplantation 2013 16 76 53%
The pros and the cons of mTOR inhibitors in kidney transplantation 2014 5 79 57%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 IMMUNOL ORGAN TRANSPLANTAT 17 26% 2.6% 54
2 PUBL MED SOCIAL HLTH 6 80% 0.2% 4
3 KIDNEY TRANSPLANT SERV 5 27% 0.7% 15
4 AUSTRALIAN BIOANALYT SERV PTY LTD 4 50% 0.3% 6
5 NEPHROL DIALYSIS ORGAN TRANSPLANTAT 3 22% 0.7% 14
6 ALLGEMEINE PHARMAKOL 3 33% 0.3% 7
7 UNIDAD TRANSPLANTE RENAL 3 35% 0.3% 6
8 SERV TRANSPLANTAT ADULTE 2 67% 0.1% 2
9 HOSP RIM HIPERTENSAO 2 15% 0.6% 13
10 SECT RENAL TRANSPLANTAT 2 21% 0.4% 9

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000162325 STEROID WITHDRAWAL//CORTICOSTEROID WITHDRAWAL//EARLY STEROID WITHDRAWAL
2 0.0000147129 SIMULTANEOUS LIVER KIDNEY TRANSPLANTATION//DUAL ORGAN TRANSPLANTATION//COMBINED TRANSPLANTATION
3 0.0000127284 SUBCLINICAL REJECTION//PROTOCOL BIOPSY//ALBERTA TRANSPLANT PL GENOM
4 0.0000114241 MYCOPHENOLIC ACID//MYCOPHENOLIC ACID GLUCURONIDE//MYCOPHENOLATE MOFETIL
5 0.0000106189 POSTTRANSPLANTATION HYPERTENSION//POST TRANSPLANT NEPHROTIC SYNDROME//POST TRANSPLANT HYPERTENSION
6 0.0000105710 BASILIXIMAB//THYMOGLOBULIN//DACLIZUMAB
7 0.0000104232 CYP3A5//TACROLIMUS//CYTOCHROME P450 3A5
8 0.0000087824 FK 506//FUJISAWA AMER//FUJISAWA AMER INC
9 0.0000080681 NEORAL//C2 MONITORING//C 2 MONITORING
10 0.0000072110 POSTTRANSPLANT HYPERLIPIDEMIA//ABT LEBENSMITTELSICHERHEIT 1//APOLIPOPROTEIN DISTRIBUTION