Class information for:
Level 1: PYRROLE IMIDAZOLE POLYAMIDE//DISTAMYCIN//MINOR GROOVE BINDERS

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
3216 1959 36.1 73%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2357 3920 DUOCARMYCINS//PYRROLOBENZODIAZEPINE//PYRROLE IMIDAZOLE POLYAMIDE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PYRROLE IMIDAZOLE POLYAMIDE Author keyword 79 94% 1% 29
2 DISTAMYCIN Author keyword 54 64% 3% 54
3 MINOR GROOVE BINDERS Author keyword 37 65% 2% 35
4 NETROPSIN Author keyword 33 59% 2% 37
5 TALLIMUSTINE Author keyword 21 85% 1% 11
6 MINOR GROOVE BINDER Author keyword 19 44% 2% 33
7 MINOR GROOVE Author keyword 17 38% 2% 36
8 LEXITROPSINS Author keyword 15 88% 0% 7
9 PYRROLE IMIDAZOLE POLYAMIDES Author keyword 15 88% 0% 7
10 HOECHST 33258 Author keyword 14 30% 2% 40

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 PYRROLE IMIDAZOLE POLYAMIDE 79 94% 1% 29 Search PYRROLE+IMIDAZOLE+POLYAMIDE Search PYRROLE+IMIDAZOLE+POLYAMIDE
2 DISTAMYCIN 54 64% 3% 54 Search DISTAMYCIN Search DISTAMYCIN
3 MINOR GROOVE BINDERS 37 65% 2% 35 Search MINOR+GROOVE+BINDERS Search MINOR+GROOVE+BINDERS
4 NETROPSIN 33 59% 2% 37 Search NETROPSIN Search NETROPSIN
5 TALLIMUSTINE 21 85% 1% 11 Search TALLIMUSTINE Search TALLIMUSTINE
6 MINOR GROOVE BINDER 19 44% 2% 33 Search MINOR+GROOVE+BINDER Search MINOR+GROOVE+BINDER
7 MINOR GROOVE 17 38% 2% 36 Search MINOR+GROOVE Search MINOR+GROOVE
8 LEXITROPSINS 15 88% 0% 7 Search LEXITROPSINS Search LEXITROPSINS
9 PYRROLE IMIDAZOLE POLYAMIDES 15 88% 0% 7 Search PYRROLE+IMIDAZOLE+POLYAMIDES Search PYRROLE+IMIDAZOLE+POLYAMIDES
10 HOECHST 33258 14 30% 2% 40 Search HOECHST+33258 Search HOECHST+33258

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 NETROPSIN 252 64% 13% 249
2 DISTAMYCIN 251 58% 15% 291
3 PYRROLE IMIDAZOLE POLYAMIDES 199 77% 7% 135
4 DISTAMYCIN A 168 69% 7% 144
5 LEXITROPSINS 165 91% 4% 69
6 HAIRPIN POLYAMIDES 148 90% 3% 64
7 COVALENT PEPTIDE DIMERS 103 97% 2% 30
8 MINOR GROOVE 90 20% 21% 415
9 HAIRPIN POLYAMIDE 86 90% 2% 37
10 SEQUENCE SPECIFIC RECOGNITION 83 47% 7% 130

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Recognition of the DNA minor groove by pyrrole-imidazole polyamides 2003 358 71 89%
Molecular recognition of DNA by small molecules 2001 594 84 71%
Synthesis and biological properties of sequence-specific DNA-alkylating pyrrole-imidazole polyamides 2006 60 49 80%
Sequence-specific DNA recognition by polyamides 1999 217 41 88%
DNA minor-groove recognition by small molecules 2001 268 231 74%
Non-covalent ligand/DNA interactions: Minor groove binding agents 2007 93 108 57%
Designed sequence-specific minor groove ligands 2000 115 77 92%
Regulation of gene expression by synthetic DNA-binding ligands 2005 65 97 87%
Sequence-specific DNA minor groove binders. Design and synthesis of netropsin and distamycin analogues 1998 223 256 75%
Anticancer activities of alkylating pyrrole-imidazole polyamides with specific sequence recognition 2010 23 46 80%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MED CHEM DRUG TECHNOL 8 41% 0.8% 16
2 CANC UK DRUG DNA INTERACT GRP 6 28% 0.9% 17
3 THER EUT AREA ONCOL IMMUNOL 3 100% 0.2% 3
4 ADV SCI HUMANITIES 2 11% 1.0% 20
5 CENT XRAY RADIOL 2 67% 0.1% 2
6 CHEM BIOL BIOORGAN CHEM MOL ENGN 2 67% 0.1% 2
7 MOL RADIAT 2 67% 0.1% 2
8 ONCOL PRECLIN 2 67% 0.1% 2
9 PHARMACOL ANTITUMORALE MOL 2 67% 0.1% 2
10 INNOVAT THER Y GRP 2 33% 0.2% 4

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000181282 DUOCARMYCINS//CC 1065//DUOCARMYCIN
2 0.0000166274 PENTAMIDINE//DIAMIDINES//AROMATIC DIAMIDINES
3 0.0000107296 AN 9//SABARUBICIN//AN 7
4 0.0000100331 HETERO ASSOCIATION//HETEROASSOCIATION//ACTINOMYCINS
5 0.0000098904 POLYACENAPHTHYLENE//DNA CLEARING//BISBENZIMIDE HOECHST 33342
6 0.0000084354 PYRROLOBENZODIAZEPINE//PYRROLOBENZODIAZEPINES//PYRROLO2 1 C1 4BENZODIAZEPINES
7 0.0000084224 ECHINOMYCIN//STREPTOMYCES ALBOFLAVUS 313//PIPERAZIC ACID
8 0.0000081986 DNA CURVATURE//A TRACT//DNA FLEXIBILITY
9 0.0000057336 CATIONIC PORPHYRIN//OUTSIDE BINDING//CATIONIC PORPHYRINS
10 0.0000057200 PYRAZOLOACRIDINE//C 1311//IMIDAZOACRIDINONES