Class information for:
Level 1: METHOTREXATE//METHOTREXATE POLYGLUTAMATES//MX 68

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
3580 1877 35.5 72%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
389 16325 RHEUMATOID ARTHRITIS//RHEUMATOLOGY//RHEUMATOL

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 METHOTREXATE Author keyword 83 12% 33% 625
2 METHOTREXATE POLYGLUTAMATES Author keyword 18 65% 1% 17
3 MX 68 Author keyword 5 63% 0% 5
4 METHOTREXATE PNEUMONITIS Author keyword 4 75% 0% 3
5 MTX TOXICITY Author keyword 4 75% 0% 3
6 LONGTERM TREATMENT Author keyword 3 57% 0% 4
7 CH 1504 Author keyword 3 100% 0% 3
8 THERAPEUTIC SEGMENT Author keyword 3 100% 0% 3
9 DISEASE MODIFYING ANTIRHEUMATIC DRUGS Author keyword 3 12% 1% 24
10 METHOTREXATE TOXICITY Author keyword 3 32% 0% 8

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 METHOTREXATE 83 12% 33% 625 Search METHOTREXATE Search METHOTREXATE
2 METHOTREXATE POLYGLUTAMATES 18 65% 1% 17 Search METHOTREXATE+POLYGLUTAMATES Search METHOTREXATE+POLYGLUTAMATES
3 MX 68 5 63% 0% 5 Search MX+68 Search MX+68
4 METHOTREXATE PNEUMONITIS 4 75% 0% 3 Search METHOTREXATE+PNEUMONITIS Search METHOTREXATE+PNEUMONITIS
5 MTX TOXICITY 4 75% 0% 3 Search MTX+TOXICITY Search MTX+TOXICITY
6 LONGTERM TREATMENT 3 57% 0% 4 Search LONGTERM+TREATMENT Search LONGTERM+TREATMENT
7 CH 1504 3 100% 0% 3 Search CH+1504 Search CH+1504
8 THERAPEUTIC SEGMENT 3 100% 0% 3 Search THERAPEUTIC+SEGMENT Search THERAPEUTIC+SEGMENT
9 DISEASE MODIFYING ANTIRHEUMATIC DRUGS 3 12% 1% 24 Search DISEASE+MODIFYING+ANTIRHEUMATIC+DRUGS Search DISEASE+MODIFYING+ANTIRHEUMATIC+DRUGS
10 METHOTREXATE TOXICITY 3 32% 0% 8 Search METHOTREXATE+TOXICITY Search METHOTREXATE+TOXICITY

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 LOW DOSE METHOTREXATE 186 34% 24% 451
2 PULSE METHOTREXATE 169 72% 7% 132
3 TERM PROSPECTIVE TRIAL 42 83% 1% 24
4 COMBINED CYCLOPHOSPHAMIDE 32 78% 1% 21
5 POLYGLUTAMATE CONCENTRATIONS 31 92% 1% 12
6 LONG TERM METHOTREXATE 26 63% 1% 26
7 2ND LINE DRUGS 22 40% 2% 44
8 ORAL METHOTREXATE 19 32% 3% 48
9 LEUCOVORIN FOLINIC ACID 18 83% 1% 10
10 FOLATE PATHWAY 15 68% 1% 13

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Methotrexate in Rheumatoid Arthritis: Optimizing Therapy Among Different Formulations. Current and Emerging Paradigms 2014 9 42 69%
Low-dose methotrexate: A mainstay in the treatment of rheumatoid arthritis 2005 200 126 65%
Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative 2009 159 94 48%
Assessment and management of methotrexate hepatotoxicity in psoriasis patients: report from a consensus conference to evaluate current practice and identify key questions toward optimizing methotrexate use in the clinic 2011 28 45 58%
Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis 2008 99 61 46%
Methotrexate pharmacogenetics in rheumatoid arthritis: a status report 2013 9 59 73%
Molecular action of methotrexate in inflammatory diseases 2002 193 91 38%
Methotrexate and liver fibrosis in people with psoriasis: a systematic review of observational studies 2014 5 25 56%
Effect of genetic polymorphisms in the folate pathway on methotrexate therapy in rheumatic diseases 2011 18 85 64%
Clinical pharmacokinetics of low-dose pulse methotrexate in rheumatoid arthritis 1996 113 81 75%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 ADV TRAINING HLTH SCI TECHNOL 3 50% 0.2% 4
2 HIGHER HLTH SCI NORTH ISCS N 2 67% 0.1% 2
3 MOL ONCOL GRP CI 2 26% 0.3% 6
4 HEALTHCARE QUAL OUTCOMES 1 50% 0.1% 2
5 SF IOAN EMERGENCY HOSP 1 50% 0.1% 2
6 DRUG EVALUAT INFORMAT 1 17% 0.3% 6
7 CLIN PHARMACOL GENET 1 16% 0.3% 6
8 DERMATOONCOL EXCELLENCE 1 40% 0.1% 2
9 ABEL SALAZAR BIOMED SCI ICBAS 1 13% 0.3% 6
10 ABORATING MOL BIOL NOVEL STRATEGIES TRE 1 50% 0.1% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000192510 SULFASALAZINE//SULPHASALAZINE//2ND LINE AGENT
2 0.0000188105 7 HYDROXYMETHOTREXATE//GLUCARPIDASE//HIGH DOSE METHOTREXATE
3 0.0000160147 STEROID DEPENDENT ASTHMA//STEROID SPARING AGENTS//ALLERGY P CARE
4 0.0000134406 AG LES MARKUS KRANKENHAUS//DESERT ORTHOPED//DISEASE MODIFYING ANTI RHEUMATIC DRUGS DMARD
5 0.0000129868 RHEUMATOLOTA KU//MDR I//DANINI HOSP
6 0.0000122409 ABATACEPT//TOCILIZUMAB//DISEASE MODIFYING ANTIRHEUMATIC DRUGS
7 0.0000110526 DISSOLUCYTOSIS//METALLIC GOLD//AURANOFIN
8 0.0000108149 PULMONARY RHEUMATOID NODULE//RHEUMATOID LUNG//RHEUMATOID PLEURITIS
9 0.0000106781 JOINT SPACE MEASUREMENT//COMPUTER AIDED JOINT SPACE ANALYSIS//SHARP SCORE
10 0.0000106050 INTESTINAL DAMAGE//SOYBEAN CONCENTRATE//ADJUVANT FREUND INDUCED ARTHRITIS