Class information for:
Level 1: CYTOSINE DEAMINASE//SUICIDE GENE THERAPY//HERPES SIMPLEX VIRUS THYMIDINE KINASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
3583 1877 43.7 87%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1512 6953 ONCOLYTIC VIRUS//VIROTHERAPY//CYTOSINE DEAMINASE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CYTOSINE DEAMINASE Author keyword 83 53% 6% 110
2 SUICIDE GENE THERAPY Author keyword 79 52% 6% 106
3 HERPES SIMPLEX VIRUS THYMIDINE KINASE Author keyword 65 55% 4% 81
4 SUICIDE GENE Author keyword 44 39% 5% 89
5 THYMIDINE KINASE Author keyword 33 20% 8% 144
6 BYSTANDER EFFECT Author keyword 32 24% 6% 115
7 GANCICLOVIR Author keyword 26 16% 8% 152
8 HSV TK Author keyword 24 42% 2% 44
9 HSVTK Author keyword 20 62% 1% 21
10 CANCER GENE THERAPY Journal 20 10% 10% 185

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 CYTOSINE DEAMINASE 83 53% 6% 110 Search CYTOSINE+DEAMINASE Search CYTOSINE+DEAMINASE
2 SUICIDE GENE THERAPY 79 52% 6% 106 Search SUICIDE+GENE+THERAPY Search SUICIDE+GENE+THERAPY
3 HERPES SIMPLEX VIRUS THYMIDINE KINASE 65 55% 4% 81 Search HERPES+SIMPLEX+VIRUS+THYMIDINE+KINASE Search HERPES+SIMPLEX+VIRUS+THYMIDINE+KINASE
4 SUICIDE GENE 44 39% 5% 89 Search SUICIDE+GENE Search SUICIDE+GENE
5 THYMIDINE KINASE 33 20% 8% 144 Search THYMIDINE+KINASE Search THYMIDINE+KINASE
6 BYSTANDER EFFECT 32 24% 6% 115 Search BYSTANDER+EFFECT Search BYSTANDER+EFFECT
7 GANCICLOVIR 26 16% 8% 152 Search GANCICLOVIR Search GANCICLOVIR
8 HSV TK 24 42% 2% 44 Search HSV+TK Search HSV+TK
9 HSVTK 20 62% 1% 21 Search HSVTK Search HSVTK
10 GEF GENE 18 89% 0% 8 Search GEF+GENE Search GEF+GENE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 VIRUS THYMIDINE KINASE 98 41% 10% 185
2 THYMIDINE KINASE GENE 94 26% 17% 318
3 EXPERIMENTAL BRAIN TUMORS 77 43% 7% 136
4 5 FLUOROCYTOSINE 74 41% 7% 139
5 CYTOSINE DEAMINASE GENE 58 49% 5% 87
6 CYTOSINE DEAMINASE 44 31% 6% 122
7 THYMIDINE KINASE GENES 44 56% 3% 53
8 SUICIDE GENE 44 30% 6% 122
9 VECTOR PRODUCER CELLS 44 72% 2% 34
10 EXPERIMENTAL GLIOMAS 39 63% 2% 39

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CANCER GENE THERAPY 20 10% 10% 185

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Gene-Directed Enzyme Prodrug Therapy 2015 1 103 62%
Suicide gene therapy in cancer: Where do we stand now? 2012 47 164 47%
Gene directed Enzyme/Prodrug therapy of cancer: Historical appraisal and future prospectives 2001 163 161 68%
Prognostic utility of gene therapy with herpes simplex virus thymidine kinase for patients with high-grade malignant gliomas: a systematic review and meta analysis 2014 2 29 69%
Prodrug cancer gene therapy 2008 61 98 39%
Bystander effect in herpes simplex virus-thymidine kinase/ganciclovir cancer gene therapy: Role of gap-junctional intercellular communication 2000 225 145 42%
Adenovirus Mediated Herpes Simplex Virus-Thymidine Kinase/Ganciclovir Gene Therapy for Resectable Malignant Glioma 2009 24 105 66%
Gene therapy - designer promoters for tumour targeting 2000 147 72 54%
Introduction to the background, principles, and state of the art in suicide gene therapy 2005 53 78 62%
Prodrug activation enzymes in cancer gene therapy 2000 134 113 53%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 UPJOHN 4713 6 100% 0.2% 4
2 SERV CHIRURG ABDOMINALE THORAC 5 63% 0.3% 5
3 BIOL TUMEURS THER IE GEN 3 100% 0.2% 3
4 BASIC CARDIOVASC SECT 3 40% 0.3% 6
5 THYROID STUDY UNIT 2 19% 0.6% 11
6 GENE VIRAL THER Y GRP 2 67% 0.1% 2
7 GRP VECTEURS GENOM THER IE GEN 2 67% 0.1% 2
8 UPJOHN 4302 2 67% 0.1% 2
9 URA 1463 2 67% 0.1% 2
10 MATSUNAGA CONTE PROSTATE CANC 2 23% 0.4% 7

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000257166 GENETIC RADIOTHERAPY//GENE RADIOTHERAPY//PEDIAT MICROBIOL IMMUNOL RADIOL
2 0.0000152754 ADV CELL MOL THER Y//SHUNDE PEOPLES HOSP//TUMOR VACCINE
3 0.0000151040 CB1954//ADEPT//ANTIBODY DIRECTED ENZYME PRODRUG THERAPY
4 0.0000143008 TUMOR TROPISM//MOL NEUROTHER Y IMAGING//VET BIOCHEM IMMUNOL
5 0.0000141861 BIKDD//MITOCHONDRIAL CYTOCHROME C RELEASE//BAX OVEREXPRESSION
6 0.0000139620 ONCOLYTIC VIRUS//VIROTHERAPY//ONCOLYTIC ADENOVIRUS
7 0.0000116974 MOL MED GENE THER Y UNIT//GUTLESS//HELPER DEPENDENT ADENOVIRUS
8 0.0000103588 HSV1 TK//FIAU//RADIOCHEM CYCLOTRON CORE IL
9 0.0000080812 RETROVIRAL VECTORS//RETROVIRAL VECTOR//SELECTIVE AMPLIFIER GENE
10 0.0000062270 GENE THER Y S//PATHOTROPIC TARGETING//RETROVIRAL ENTRY