Class information for:
Level 1: OATP1B1//SLCO1B1//OATP

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
4101 1771 42.7 87%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
408 16067 STATINS//EZETIMIBE//SIMVASTATIN

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 OATP1B1 Author keyword 115 76% 5% 80
2 SLCO1B1 Author keyword 96 76% 4% 67
3 OATP Author keyword 42 48% 4% 64
4 MOL PHARMACOKINET Address 35 39% 4% 71
5 ORGANIC ANION TRANSPORTING POLYPEPTIDE Author keyword 27 50% 2% 39
6 ORGANIC ANION TRANSPORTING POLYPEPTIDE 1B1 Author keyword 21 85% 1% 11
7 CYP2C8 Author keyword 16 31% 2% 42
8 ESTRONE 3 SULFATE Author keyword 14 65% 1% 13
9 SANDWICH CULTURED HEPATOCYTES Author keyword 12 63% 1% 12
10 ORGANIC ANION TRANSPORTING POLYPEPTIDE 1B3 Author keyword 12 86% 0% 6

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 OATP1B1 115 76% 5% 80 Search OATP1B1 Search OATP1B1
2 SLCO1B1 96 76% 4% 67 Search SLCO1B1 Search SLCO1B1
3 OATP 42 48% 4% 64 Search OATP Search OATP
4 ORGANIC ANION TRANSPORTING POLYPEPTIDE 27 50% 2% 39 Search ORGANIC+ANION+TRANSPORTING+POLYPEPTIDE Search ORGANIC+ANION+TRANSPORTING+POLYPEPTIDE
5 ORGANIC ANION TRANSPORTING POLYPEPTIDE 1B1 21 85% 1% 11 Search ORGANIC+ANION+TRANSPORTING+POLYPEPTIDE+1B1 Search ORGANIC+ANION+TRANSPORTING+POLYPEPTIDE+1B1
6 CYP2C8 16 31% 2% 42 Search CYP2C8 Search CYP2C8
7 ESTRONE 3 SULFATE 14 65% 1% 13 Search ESTRONE+3+SULFATE Search ESTRONE+3+SULFATE
8 SANDWICH CULTURED HEPATOCYTES 12 63% 1% 12 Search SANDWICH+CULTURED+HEPATOCYTES Search SANDWICH+CULTURED+HEPATOCYTES
9 ORGANIC ANION TRANSPORTING POLYPEPTIDE 1B3 12 86% 0% 6 Search ORGANIC+ANION+TRANSPORTING+POLYPEPTIDE+1B3 Search ORGANIC+ANION+TRANSPORTING+POLYPEPTIDE+1B3
10 CERIVASTATIN 11 29% 2% 33 Search CERIVASTATIN Search CERIVASTATIN

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 C SLC21A6 134 100% 2% 37
2 OATP C SLC21A6 102 74% 4% 75
3 HEPATIC UPTAKE 95 35% 12% 220
4 ANION TRANSPORTING POLYPEPTIDE 88 59% 6% 99
5 SLCO1B1 POLYMORPHISM 83 73% 4% 64
6 MULTIPLE DOSE PRAVASTATIN 49 94% 1% 17
7 OATP C 44 57% 3% 52
8 PLASMA PRAVASTATIN CONCENTRATIONS 42 94% 1% 15
9 OATP1B1 40 71% 2% 32
10 SIMVASTATIN ACID 36 69% 2% 31

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Membrane transporters in drug development 2010 789 205 34%
Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake 2011 164 220 77%
Impact of OATP transporters on pharmacokinetics 2009 262 147 86%
Clinical significance of organic anion transporting polypeptides (OATPs) in drug disposition: their roles in hepatic clearance and intestinal absorption 2013 47 152 63%
The SLCO (former SLC21) superfamily of transporters 2013 39 149 66%
The Expression and Function of Organic Anion Transporting Polypeptides in Normal Tissues and in Cancer 2012 68 82 67%
Drug interactions with lipid-lowering drugs: Mechanisms and clinical relevance 2006 325 143 72%
Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family 2008 189 124 71%
OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies 2012 81 292 48%
Impact of Genetic Variation in OATP Transporters to Drug Disposition and Response 2013 21 137 84%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MOL PHARMACOKINET 35 39% 4.0% 71
2 RIKEN INNOVAT 8 43% 0.8% 15
3 CNS PAIN INNOVAT MED DMPK 6 100% 0.2% 4
4 SUGIYAMA 5 33% 0.7% 13
5 MOL BIOPHARMACEUT 3 29% 0.6% 10
6 CARDIOVASC METAB DIS INNOVAT MED DMPK 3 100% 0.2% 3
7 TOKYO NEW DRUG S 1 3 40% 0.3% 6
8 MEMBRANE TRANSPORT BIOPHARMACEUT 2 22% 0.6% 10
9 RETINAL THER EUT GRP 2 38% 0.3% 5
10 NAT PROD CLIN PHARMACOL 2 67% 0.1% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000237990 STATIN MYOPATHY//STATIN INTOLERANCE//MYALGIA
2 0.0000190657 ROSUVASTATIN CALCIUM//ATORVASTATIN CALCIUM//EZETIMIBE GLUCURONIDE
3 0.0000128263 CYP3A//COCKTAIL//MECHANISM BASED INHIBITION
4 0.0000113285 ORGANIC CATION TRANSPORTER//ORGANIC ANION TRANSPORTER//ORGANIC CATION TRANSPORT
5 0.0000096940 MRP1//MULTIDRUG RESISTANCE ASSOCIATED PROTEIN//DUBIN JOHNSON SYNDROME
6 0.0000096328 INTERSPECIES SCALING//DMPK TRANSLAT SCI//WELL STIRRED MODEL
7 0.0000095154 NK 104//PITAVASTATIN//CAS 147526 32 7
8 0.0000093729 GRAPEFRUIT JUICE//HERB DRUG INTERACTIONS//BERGAMOTTIN
9 0.0000086445 PRAVASTATIN//HMG COA REDUCTASE INHIBITOR//COMPACTIN
10 0.0000085890 ABCG2//BCRP//BREAST CANCER RESISTANCE PROTEIN