Class information for:
Level 1: FLT3//FLT3 ITD//NPM1

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
4271 1740 45.8 92%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
81 26583 MYELODYSPLASTIC SYNDROMES//ACUTE MYELOID LEUKEMIA//LEUKEMIA

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FLT3 Author keyword 246 65% 13% 234
2 FLT3 ITD Author keyword 117 72% 5% 92
3 NPM1 Author keyword 35 49% 3% 53
4 INTERNAL TANDEM DUPLICATION Author keyword 35 81% 1% 21
5 NPM1 MUTATIONS Author keyword 27 92% 1% 11
6 FLT3 GENE Author keyword 24 91% 1% 10
7 FLT3 MUTATIONS Author keyword 23 69% 1% 20
8 FLT3 LIGAND Author keyword 22 37% 3% 49
9 NPM1 MUTATION Author keyword 19 68% 1% 17
10 FLT3 INTERNAL TANDEM DUPLICATION Author keyword 18 83% 1% 10

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 FLT3 246 65% 13% 234 Search FLT3 Search FLT3
2 FLT3 ITD 117 72% 5% 92 Search FLT3+ITD Search FLT3+ITD
3 NPM1 35 49% 3% 53 Search NPM1 Search NPM1
4 INTERNAL TANDEM DUPLICATION 35 81% 1% 21 Search INTERNAL+TANDEM+DUPLICATION Search INTERNAL+TANDEM+DUPLICATION
5 NPM1 MUTATIONS 27 92% 1% 11 Search NPM1+MUTATIONS Search NPM1+MUTATIONS
6 FLT3 GENE 24 91% 1% 10 Search FLT3+GENE Search FLT3+GENE
7 FLT3 MUTATIONS 23 69% 1% 20 Search FLT3+MUTATIONS Search FLT3+MUTATIONS
8 FLT3 LIGAND 22 37% 3% 49 Search FLT3+LIGAND Search FLT3+LIGAND
9 NPM1 MUTATION 19 68% 1% 17 Search NPM1+MUTATION Search NPM1+MUTATION
10 FLT3 INTERNAL TANDEM DUPLICATION 18 83% 1% 10 Search FLT3+INTERNAL+TANDEM+DUPLICATION Search FLT3+INTERNAL+TANDEM+DUPLICATION

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 INTERNAL TANDEM DUPLICATION 513 59% 34% 583
2 NORMAL CYTOGENETICS 145 60% 9% 158
3 NORMAL KARYOTYPE 120 43% 12% 212
4 NUCLEOPHOSMIN NPM1 75 76% 3% 53
5 NPM1 MUTATIONS 57 61% 4% 61
6 AML 53 19% 15% 255
7 STUDY GROUP ULM 42 70% 2% 35
8 CYTOPLASMIC NUCLEOPHOSMIN 41 55% 3% 51
9 32D CELLS 38 71% 2% 30
10 MURINE FLT3 37 74% 2% 28

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification? 2007 255 93 56%
FLT3 as a therapeutic target in AML: still challenging after all these years 2010 127 123 82%
The role of FLT3 in haematopoietic malignancies 2003 394 116 73%
Molecular Genetics of Adult Acute Myeloid Leukemia: Prognostic and Therapeutic Implications 2011 170 76 46%
FLT3 tyrosine kinase inhibitors in acute myeloid leukemia: clinical implications and limitations 2014 13 75 88%
The roles of FLT3 in hematopoiesis and leukemia 2002 622 131 74%
Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications 2015 2 55 55%
FLT3 inhibition: a moving and evolving target in acute myeloid leukaemia 2013 23 108 84%
Acute myeloid leukemia carrying cytoplasmic/mutated nucleophosmin (NPMc(+) AML): biologic and clinical features 2007 189 115 30%
FLT3 inhibition in acute myeloid leukaemia 2007 44 83 92%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 LEUKEMIA DIAGNOST 10 33% 1.4% 25
2 MICROBIOL VIROL IMMUNOL MED GENET 10 63% 0.6% 10
3 ALLIANCE CLIN TRIALS ONCOL STAT DATA 8 70% 0.4% 7
4 CLIN COOPERAT GRP LEUKEMIA 6 28% 1.1% 19
5 MED ONCOL HEMATOL NEOPLASIA 5 55% 0.3% 6
6 LEUKAEMIA DIAGNOST 4 75% 0.2% 3
7 CLIN COOPERAT GRP ACUTE LEUKEMIAS 3 60% 0.2% 3
8 HEMATOL HEMOSTASIS ONCOL STEM CELL TRANSPL 3 11% 1.3% 23
9 CELL BIOL ANAT PHYSIOL SCI 2 67% 0.1% 2
10 ADULT LEUKEMIA PROGRAM 2 25% 0.4% 7

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000197189 ACUTE MYELOID LEUKEMIA//GEMTUZUMAB OZOGAMICIN//AML
2 0.0000176557 LEUKEMIA STEM CELLS//EXPT THER EUT TRANSLAT ONCOL PROGRAM//LEUKEMIC STEM CELL
3 0.0000147590 NUCLEOPHOSMIN//NUCLEOPHOSMIN B23//GLTSCR2
4 0.0000138541 PDXP//SITEP PHASE UNIT 1//DIOC23
5 0.0000129956 NUP98//T711P15P15//DDX10
6 0.0000077956 MLL//MLL GENE//11Q23
7 0.0000072918 CXXC5//THEOPHYLLAMINE//BIOCHIP ARRAY
8 0.0000067086 RUNX3//AML1 ETO//AML1
9 0.0000065504 IDH1//IDH2//ISOCITRATE DEHYDROGENASE 1
10 0.0000062361 C EBP BETA//C EBP DELTA//C EBP