Class information for:
Level 1: ACYCLIC NUCLEOSIDE PHOSPHONATES//ACYCLIC NUCLEOSIDE PHOSPHONATE//PMEA

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
4490 1703 27.6 69%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
77 26633 NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS//NUCLEOSIDES & NUCLEOTIDES//NUCLEOSIDES

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ACYCLIC NUCLEOSIDE PHOSPHONATES Author keyword 56 64% 3% 55
2 ACYCLIC NUCLEOSIDE PHOSPHONATE Author keyword 32 85% 1% 17
3 PMEA Author keyword 25 58% 2% 28
4 PMEDAP Author keyword 23 100% 1% 10
5 PMEG Author keyword 23 100% 1% 10
6 ACYCLIC NUCLEOTIDE ANALOGUES Author keyword 23 72% 1% 18
7 ALKYLATION ELIMINATION Author keyword 20 100% 1% 9
8 HPMPA Author keyword 18 83% 1% 10
9 POLYMETHYLENE ANALOGUES Author keyword 17 100% 0% 8
10 CIDOFOVIR Author keyword 15 18% 5% 78

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 ACYCLIC NUCLEOSIDE PHOSPHONATES 56 64% 3% 55 Search ACYCLIC+NUCLEOSIDE+PHOSPHONATES Search ACYCLIC+NUCLEOSIDE+PHOSPHONATES
2 ACYCLIC NUCLEOSIDE PHOSPHONATE 32 85% 1% 17 Search ACYCLIC+NUCLEOSIDE+PHOSPHONATE Search ACYCLIC+NUCLEOSIDE+PHOSPHONATE
3 PMEA 25 58% 2% 28 Search PMEA Search PMEA
4 PMEDAP 23 100% 1% 10 Search PMEDAP Search PMEDAP
5 PMEG 23 100% 1% 10 Search PMEG Search PMEG
6 ACYCLIC NUCLEOTIDE ANALOGUES 23 72% 1% 18 Search ACYCLIC+NUCLEOTIDE+ANALOGUES Search ACYCLIC+NUCLEOTIDE+ANALOGUES
7 ALKYLATION ELIMINATION 20 100% 1% 9 Search ALKYLATION+ELIMINATION Search ALKYLATION+ELIMINATION
8 HPMPA 18 83% 1% 10 Search HPMPA Search HPMPA
9 POLYMETHYLENE ANALOGUES 17 100% 0% 8 Search POLYMETHYLENE+ANALOGUES Search POLYMETHYLENE+ANALOGUES
10 CIDOFOVIR 15 18% 5% 78 Search CIDOFOVIR Search CIDOFOVIR

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ACYCLIC NUCLEOTIDE ANALOGS 73 73% 3% 56
2 ACYCLIC NUCLEOSIDE PHOSPHONATES 65 46% 6% 107
3 NUCLEOTIDE ANALOGS 58 37% 7% 125
4 9 2 PHOSPHONYLMETHOXYETHYLADENINE 56 58% 4% 65
5 ANTIRETROVIRUS ACTIVITY 53 79% 2% 34
6 ANTI DNA VIRUS 38 64% 2% 37
7 S 1 3 HYDROXY 2 PHOSPHONYLMETHOXYPROPYLCYTOSINE 36 49% 3% 54
8 PMEA 36 54% 3% 46
9 9 2 PHOSPHONYLMETHOXYETHYLADENINE PMEA 28 68% 1% 25
10 PHOSPHONYLMETHOXYALKYL DERIVATIVES 26 57% 2% 31

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Acyclic nucleoside phosphonates: A key class of antiviral drugs 2005 286 124 52%
Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir 1999 177 40 75%
Highlights in the Discovery of Antiviral Drugs: A Personal Retrospective 2010 53 94 41%
The acyclic nucleoside phosphonates from inception to clinical use: Historical perspective 2007 71 104 62%
Phosphonomethoxyalkyl analogs of nucleotides 2003 151 336 64%
Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base 1999 106 104 80%
A 40-Year Journey in Search of Selective Antiviral Chemotherapy 2011 44 116 34%
The Acyclic Nucleoside Phosphonates (ANPs): Antonin Holy's Legacy 2013 8 84 60%
HPMPC (cidofovir), PMEA (adefovir) and related acyclic nucleoside phosphonate analogues: A review of their pharmacology and clinical potential in the treatment of viral infections 1997 170 129 69%
Antiviral acyclic nucleoside phosphonates structure activity studies 2006 32 18 89%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 BK PROJECT TEAM 21 14 65% 0.8% 13
2 CHEMEXPT CLIN CHEMOTHER Y PROGRAM 14 100% 0.4% 7
3 CHEMDEV THER EUT PROGRAM 9 83% 0.3% 5
4 MED 0676 9 83% 0.3% 5
5 SAN DIEGO VET MED FDN 3 100% 0.2% 3
6 PROJECT TEAM BK 21 3 37% 0.4% 7
7 CHIM PHYS ORGAN 3 30% 0.4% 7
8 NOVEL ANTIVIRALS ANTINEOPLAST 2 44% 0.2% 4
9 CHEMBARBARA ANN KARMANOS CANC 2 67% 0.1% 2
10 INSERM U544 2 67% 0.1% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000148782 OXETANOCIN A//CARBOCYCLIC OXETANOCIN//UP A CNRS 6011
2 0.0000119889 PRONUCLEOTIDES//PROTIDE//PRONUCLEOTIDE
3 0.0000116162 ACYCLOVIR RESISTANCE//ASP2151//BAY 57 1293
4 0.0000112242 ISONUCLEOSIDE//ISONUCLEOSIDES//AZT ANALOGS
5 0.0000099591 TRIAZOLE NUCLEOSIDES//COMBINATORIAL CHEM DRUG DISCOVERY//GILEAD SCI IOCB
6 0.0000098375 CARBOCYCLIC NUCLEOSIDES//S ADENOSYLHOMOCYSTEINE HYDROLASE//CARBOCYCLIC NUCLEOSIDE
7 0.0000096447 BV ARAU//5 ETHYL 2 DEOXYURIDINE//BCNA
8 0.0000091303 KETONUCLEOSIDES//UNSATURATED NUCLEOSIDES//EXOMETHYLENE NUCLEOSIDES
9 0.0000078466 AGELASINE//PL BIOL SAKYO KU//ASMARINE
10 0.0000064008 ACYCLOVIR//9 CARBOXYMETHOXYMETHYLGUANINE//VALACYCLOVIR