Class information for:
Level 1: FAMILIAL HYPERCHOLESTEROLEMIA//FAMILIAL HYPERCHOLESTEROLAEMIA//LDL RECEPTOR GENE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
4643 1678 33.1 73%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
56 28576 CHOLESTERYL ESTER TRANSFER PROTEIN//JOURNAL OF LIPID RESEARCH//HIGH DENSITY LIPOPROTEIN

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FAMILIAL HYPERCHOLESTEROLEMIA Author keyword 239 43% 25% 422
2 FAMILIAL HYPERCHOLESTEROLAEMIA Author keyword 89 55% 7% 112
3 LDL RECEPTOR GENE Author keyword 42 75% 2% 30
4 FAMILIAL DEFECTIVE APOLIPOPROTEIN B 100 Author keyword 36 79% 1% 23
5 LOW DENSITY LIPOPROTEIN RECEPTOR GENE Author keyword 35 81% 1% 21
6 LOW DENSITY LIPOPROTEIN RECEPTOR Author keyword 31 24% 7% 113
7 LDLR GENE Author keyword 28 81% 1% 17
8 AUTOSOMAL RECESSIVE HYPERCHOLESTEROLEMIA Author keyword 27 92% 1% 11
9 LDL RECEPTOR MUTATIONS Author keyword 23 86% 1% 12
10 LDL RECEPTOR Author keyword 22 17% 7% 121

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 FAMILIAL HYPERCHOLESTEROLEMIA 239 43% 25% 422 Search FAMILIAL+HYPERCHOLESTEROLEMIA Search FAMILIAL+HYPERCHOLESTEROLEMIA
2 FAMILIAL HYPERCHOLESTEROLAEMIA 89 55% 7% 112 Search FAMILIAL+HYPERCHOLESTEROLAEMIA Search FAMILIAL+HYPERCHOLESTEROLAEMIA
3 LDL RECEPTOR GENE 42 75% 2% 30 Search LDL+RECEPTOR+GENE Search LDL+RECEPTOR+GENE
4 FAMILIAL DEFECTIVE APOLIPOPROTEIN B 100 36 79% 1% 23 Search FAMILIAL+DEFECTIVE+APOLIPOPROTEIN+B+100 Search FAMILIAL+DEFECTIVE+APOLIPOPROTEIN+B+100
5 LOW DENSITY LIPOPROTEIN RECEPTOR GENE 35 81% 1% 21 Search LOW+DENSITY+LIPOPROTEIN+RECEPTOR+GENE Search LOW+DENSITY+LIPOPROTEIN+RECEPTOR+GENE
6 LOW DENSITY LIPOPROTEIN RECEPTOR 31 24% 7% 113 Search LOW+DENSITY+LIPOPROTEIN+RECEPTOR Search LOW+DENSITY+LIPOPROTEIN+RECEPTOR
7 LDLR GENE 28 81% 1% 17 Search LDLR+GENE Search LDLR+GENE
8 AUTOSOMAL RECESSIVE HYPERCHOLESTEROLEMIA 27 92% 1% 11 Search AUTOSOMAL+RECESSIVE+HYPERCHOLESTEROLEMIA Search AUTOSOMAL+RECESSIVE+HYPERCHOLESTEROLEMIA
9 LDL RECEPTOR MUTATIONS 23 86% 1% 12 Search LDL+RECEPTOR+MUTATIONS Search LDL+RECEPTOR+MUTATIONS
10 LDL RECEPTOR 22 17% 7% 121 Search LDL+RECEPTOR Search LDL+RECEPTOR

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 DEFECTIVE APOLIPOPROTEIN B 100 140 79% 5% 90
2 LDL RECEPTOR GENE 87 52% 7% 118
3 B MUTATION 45 94% 1% 16
4 CAUSES HYPERCHOLESTEROLEMIA 32 80% 1% 20
5 AFRIKANERS 32 78% 1% 21
6 ASSOCIATION EXPERT PANEL 26 54% 2% 34
7 HUMAN LDL RECEPTOR 26 64% 1% 25
8 LIPOPROTEIN RECEPTOR GENE 24 34% 3% 58
9 FAMILIAL DEFECTIVE APOLIPOPROTEIN B 100 22 39% 3% 43
10 LDL RECEPTOR 21 11% 11% 178

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Mechanisms of Disease: genetic causes of familial hypercholesterolemia 2007 172 75 73%
Genetic causes of monogenic heterozygous familial hypercholesterolemia: A HuGE prevalence review 2004 142 100 88%
Integrated guidance on the care of familial hypercholesterolaemia from the International FH Foundation 2014 22 164 40%
Homozygous familial hypercholesterolemia: Current perspectives on diagnosis and treatment 2012 54 44 43%
Familial hypercholesterolemia and coronary heart disease: A HuGE association review 2004 108 76 78%
Genetic heterogeneity of autosomal dominant hypercholesterolemia 2008 78 75 71%
A review on the diagnosis, natural history, and treatment of familial hypercholesterolaemia 2003 213 77 44%
Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society 2014 20 54 33%
Integrating provision of specialist lipid services with cascade testing for familial hypercholesterolaemia 2010 22 10 100%
Familial hypercholesterolemia and estimation of US patients eligible for low-density lipoprotein apheresis after maximally tolerated lipid-Lowering therapy 2014 7 56 63%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CARDIOMETAB SERV 15 88% 0.4% 7
2 UNIDADE ID 9 83% 0.3% 5
3 GRP INVEST CARDIOVASC 8 75% 0.4% 6
4 BRITISH HEART FDN S 7 18% 2.1% 35
5 MRCC E HEART GRP 6 100% 0.2% 4
6 PONTAI MED 6 100% 0.2% 4
7 UNIT GENET BIOL TORS ATHEROSCLEROSIS 5 54% 0.4% 7
8 LIPID DISORDERS CLIN 5 27% 1.0% 17
9 INVEST MOL 5 25% 1.0% 16
10 CGH MED 4 67% 0.2% 4

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000269986 PCSK9//PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9//MIPOMERSEN
2 0.0000213981 APOLIPOPROTEIN B GENE//APOB GENE//SIGNAL PEPTIDE POLYMORPHISM
3 0.0000142652 LDL APHERESIS//LOW DENSITY LIPOPROTEIN APHERESIS//LIPOPROTEIN APHERESIS
4 0.0000133305 HYPERTHERMIC SENSITIVITY//CELLULAR CHOLESTEROL CONTENT//HIV 1 THERAPY
5 0.0000096637 LRP1B//VLDL RECEPTOR//LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN
6 0.0000095944 FIBROUS PLAQUES//CHOLESTEROL SCREENING//PREVENT SECT
7 0.0000073683 LIPOPROTEIN GLOMERULOPATHY//APOLIPOPROTEIN E//TYPE III HYPERLIPOPROTEINEMIA
8 0.0000070336 LIPOPROT UNIT//LIPOPROTEIN KINETICS//OURCE IL KINET ANAL
9 0.0000067469 CEREBROTENDINOUS XANTHOMATOSIS//CHOLESTANOL//BILE ALCOHOLS
10 0.0000066375 JOINT EFFUSIONS//JUMPING HORSE//MED BLOOD TRANSFUS UNIT