Class information for:
Level 1: JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS//NONMEM//INDIRECT RESPONSE MODELS

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
5645 1528 27.8 64%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1987 5071 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS//NONMEM

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS Journal 105 40% 14% 207
2 NONMEM Author keyword 53 28% 11% 162
3 INDIRECT RESPONSE MODELS Author keyword 40 82% 2% 23
4 PHARMACOKINET DRUG THER Y Address 21 31% 4% 56
5 PHARMACOMETRICS Author keyword 20 41% 3% 39
6 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS Journal 16 14% 7% 103
7 SAMPLING WINDOWS Author keyword 15 88% 0% 7
8 MODEL BASED DRUG DEVELOPMENT Author keyword 14 59% 1% 16
9 TURNOVER MODELS Author keyword 14 100% 0% 7
10 POPULATION PHARMACOKINETICS Author keyword 14 11% 7% 111

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 NONMEM 53 28% 11% 162 Search NONMEM Search NONMEM
2 INDIRECT RESPONSE MODELS 40 82% 2% 23 Search INDIRECT+RESPONSE+MODELS Search INDIRECT+RESPONSE+MODELS
3 PHARMACOMETRICS 20 41% 3% 39 Search PHARMACOMETRICS Search PHARMACOMETRICS
4 SAMPLING WINDOWS 15 88% 0% 7 Search SAMPLING+WINDOWS Search SAMPLING+WINDOWS
5 MODEL BASED DRUG DEVELOPMENT 14 59% 1% 16 Search MODEL+BASED+DRUG+DEVELOPMENT Search MODEL+BASED+DRUG+DEVELOPMENT
6 TURNOVER MODELS 14 100% 0% 7 Search TURNOVER+MODELS Search TURNOVER+MODELS
7 POPULATION PHARMACOKINETICS 14 11% 7% 111 Search POPULATION+PHARMACOKINETICS Search POPULATION+PHARMACOKINETICS
8 NONLINEAR MIXED EFFECTS MODELS 11 35% 2% 25 Search NONLINEAR+MIXED+EFFECTS+MODELS Search NONLINEAR+MIXED+EFFECTS+MODELS
9 MONOLIX 10 73% 1% 8 Search MONOLIX Search MONOLIX
10 NONLINEAR MIXED EFFECTS MODEL 9 32% 2% 23 Search NONLINEAR+MIXED+EFFECTS+MODEL Search NONLINEAR+MIXED+EFFECTS+MODEL

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 NONMEM 43 38% 6% 90
2 INDIRECT PHARMACODYNAMIC RESPONSES 37 75% 2% 27
3 4 BASIC MODELS 30 57% 2% 35
4 POPULATION PHARMACODYNAMIC MODEL 29 88% 1% 14
5 FISHER INFORMATION MATRIX 19 56% 2% 23
6 NATURAL CELLS 19 76% 1% 13
7 POPULATION PHARMACOKINETIC PARAMETERS 18 52% 2% 24
8 API CRITERIA 17 100% 1% 8
9 PHARMACOMETRICS 17 75% 1% 12
10 VS SEQUENTIAL ANALYSIS 15 68% 1% 13

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 105 40% 14% 207
2 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS 16 14% 7% 103

Reviews


Title Publ. year Cit. Active
references		 % act. ref.
to same field
Implementation of pharmacokinetic and pharrnacodynamic strategies in early research phases of drug discovery and development at Novartis Institute of Biomedical Research 2014 4 61 36%
Clinical pharmacology = disease progression plus drug action 2015 1 45 56%
A survey of population analysis methods and software for complex pharmacokinetic and pharmacodynamic models with examples 2007 59 23 87%
Model-based clinical drug development in the past, present and future: a commentary 2015 1 28 54%
A genetic algorithm based global search strategy for population pharmacokinetic/pharmacodynamic model selection 2015 1 8 50%
A review on estimation of stochastic differential equations for pharmacokinetic/pharmacodynamic models 2013 7 31 58%
Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research 2008 68 19 53%
Covariate selection in pharmacometric analyses: a review of methods 2015 1 34 47%
Quantitative Disease, Drug, and Trial Models 2009 44 27 59%
Early integration of pharmacokinetic and dynamic reasoning is essential for optimal development of lead compounds: strategic considerations 2009 40 5 60%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PHARMACOKINET DRUG THER Y 21 31% 3.7% 56
2 PHARMACOMETR 13 32% 2.2% 34
3 PL PHARMACOKINET 7 18% 2.4% 37
4 PHARMACOMETR GRP 7 46% 0.7% 11
5 ADV PK PD MODELING SIMULAT 6 48% 0.7% 10
6 OFF CLIN PHARMACOL BIOPHARMACEUT 6 27% 1.2% 19
7 PHARMACEUT EVALUAT 1 5 45% 0.6% 9
8 PHARMACOKINET PHARMACOMETR 5 63% 0.3% 5
9 UMR 738 4 25% 1.0% 15
10 CLIN PHARMACOL MODELLING SIMULAT 4 22% 1.1% 17

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000103483 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//DISTRIBUTION CLEARANCE//CURVE MOMENTS
2 0.0000069039 D OPTIMALITY//APPROXIMATE DESIGNS//APPROXIMATE DESIGN
3 0.0000059268 FCRN//NEONATAL FC RECEPTOR//TARGET MEDIATED DRUG DISPOSITION
4 0.0000058110 INDIVIDUAL BIOEQUIVALENCE//HIGHLY VARIABLE DRUGS//BIOEQUIVALENCE
5 0.0000055579 LYMPHOCYTE IMMUNOSUPPRESSANT SENSITIVITY TEST LIST//LYMPHOCYTE SENSITIVITY//T CELL MITOGEN
6 0.0000055444 UNLICENSED//OFF LABEL//OFF LABEL DRUG USE
7 0.0000055177 INTERSPECIES SCALING//DMPK TRANSLAT SCI//WELL STIRRED MODEL
8 0.0000049170 ETOPOSIDE PHOSPHATE//ETOPOSIDE//ORAL ETOPOSIDE
9 0.0000047487 AMINOGLYCOSIDES//AMIKACIN//TOBRAMYCIN
10 0.0000041062 NAB PACLITAXEL//CREMOPHOR EL//NEW MAT BIOL