Class information for:
Level 1: ROLIPRAM//PDE4//PHOSPHODIESTERASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
643 3133 42.0 78%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1104 9294 ROLIPRAM//PHOSPHODIESTERASE//PDE4

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ROLIPRAM Author keyword 198 56% 8% 244
2 PDE4 Author keyword 147 70% 4% 122
3 PHOSPHODIESTERASE Author keyword 115 27% 12% 369
4 PDE10A Author keyword 102 89% 2% 47
5 PDE4 INHIBITOR Author keyword 59 71% 2% 48
6 PHOSPHODIESTERASE 4 Author keyword 58 58% 2% 66
7 ROFLUMILAST Author keyword 44 54% 2% 56
8 PDE7 Author keyword 35 86% 1% 18
9 CYCLIC NUCLEOTIDE PHOSPHODIESTERASES Author keyword 35 47% 2% 55
10 PHOSPHODIESTERASE 10A Author keyword 27 83% 0% 15

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 ROLIPRAM 198 56% 8% 244 Search ROLIPRAM Search ROLIPRAM
2 PDE4 147 70% 4% 122 Search PDE4 Search PDE4
3 PHOSPHODIESTERASE 115 27% 12% 369 Search PHOSPHODIESTERASE Search PHOSPHODIESTERASE
4 PDE10A 102 89% 2% 47 Search PDE10A Search PDE10A
5 PDE4 INHIBITOR 59 71% 2% 48 Search PDE4+INHIBITOR Search PDE4+INHIBITOR
6 PHOSPHODIESTERASE 4 58 58% 2% 66 Search PHOSPHODIESTERASE+4 Search PHOSPHODIESTERASE+4
7 ROFLUMILAST 44 54% 2% 56 Search ROFLUMILAST Search ROFLUMILAST
8 PDE7 35 86% 1% 18 Search PDE7 Search PDE7
9 CYCLIC NUCLEOTIDE PHOSPHODIESTERASES 35 47% 2% 55 Search CYCLIC+NUCLEOTIDE+PHOSPHODIESTERASES Search CYCLIC+NUCLEOTIDE+PHOSPHODIESTERASES
10 PHOSPHODIESTERASE 10A 27 83% 0% 15 Search PHOSPHODIESTERASE+10A Search PHOSPHODIESTERASE+10A

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CYCLIC NUCLEOTIDE PHOSPHODIESTERASES 425 43% 24% 756
2 CAMP SPECIFIC PHOSPHODIESTERASE 324 73% 8% 247
3 AMP SPECIFIC PHOSPHODIESTERASE 261 95% 3% 89
4 ROLIPRAM 261 66% 8% 245
5 AMP PHOSPHODIESTERASE 149 64% 5% 146
6 PDE4 INHIBITORS 130 71% 3% 104
7 CAMP PHOSPHODIESTERASE 93 51% 4% 130
8 STRIATUM ENRICHED PHOSPHODIESTERASE 91 89% 1% 41
9 AFFINITY ROLIPRAM BINDING 85 100% 1% 26
10 PDE10A 83 84% 1% 46

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ADVANCES IN CYCLIC NUCLEOTIDE AND PROTEIN PHOSPHORYLATION RESEARCH 3 14% 1% 19
2 ADVANCES IN SECOND MESSENGER AND PHOSPHOPROTEIN RESEARCH 2 12% 1% 19
3 JOURNAL OF CYCLIC NUCLEOTIDE AND PROTEIN PHOSPHORYLATION RESEARCH 2 11% 0% 13
4 SECOND MESSENGERS AND PHOSPHOPROTEINS 1 13% 0% 8

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Cyclic nucleotide phosphodiesterases: Molecular regulation to clinical use 2006 698 246 72%
Advances in targeting cyclic nucleotide phosphodiesterases 2014 39 244 58%
Biochemistry and physiology of cyclic nucleotide Phosphocliesterases: Essential components in cyclic nucleotide signaling 2007 471 170 54%
Phosphodiesterase Inhibitors as a Target for Cognition Enhancement in Aging and Alzheimer's Disease: A Translational Overview 2015 3 128 59%
Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents 2006 399 334 72%
Overview of PDEs and their regulation 2007 265 168 85%
Mammalian Cyclic Nucleotide Phosphodiesterases: Molecular Mechanisms and Physiological Functions 2011 122 397 60%
CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES - FUNCTIONAL IMPLICATIONS OF MULTIPLE ISOFORMS 1995 1275 136 54%
PDE4 inhibitors: current status 2008 147 77 79%
PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization 2003 419 120 78%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PHARMACOMETR PHARMACOKINET 13 71% 0.3% 10
2 MOL PHARMACOL GRP 8 15% 1.7% 53
3 BEHAV MED PSYCHIAT 5 17% 0.8% 26
4 PULM CRIT CARE MED BRANCH 5 13% 1.1% 33
5 SACKLER PULM PHARMACOL 3 12% 0.8% 26
6 SMALL MOL CHEM 3 43% 0.2% 6
7 MATERNITE PORT ROYAL COCHIN 3 100% 0.1% 3
8 TOXICOL PHARM CHEM 3 100% 0.1% 3
9 F NES S 3 31% 0.3% 8
10 BIOCHEM D DEN 3 60% 0.1% 3

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000155537 PDE 5 INHIBITION//PDE5//PHOSPHODIESTERASE 5
2 0.0000118099 IBUDILAST//CAS 50847 11 5//221 MIYAMA
3 0.0000092132 GRAVIN//AKAP//A KINASE ANCHORING PROTEIN
4 0.0000085657 DOXOFYLLINE//ENPROFYLLINE//3H IMIDAZO4 5 CQUINOLIN 45H ONE
5 0.0000072172 TYPE II CGMP DEPENDENT PROTEIN KINASE//CGMP DEPENDENT PROTEIN KINASE//CANC MOL BIOL SECT
6 0.0000059915 1 2 3 4 TETRAHYDROPYRAZINO1 2 AINDOLES//BENZOFUROPYRIDINE//IODOLACTONISATION
7 0.0000058518 ENOXIMONE//AMRINONE//MILRINONE
8 0.0000056108 CILOSTAZOL//CLIN PHARMACOKINET PHARMACODYNAM METAB//CAS 73963 72 1
9 0.0000047416 BIOQUIM ENVELHECIMENTO DOENCAS CORRELACIONA//NPPG//BIOQUIM METABOL
10 0.0000038615 DRUG INDUCED VASCULAR INJURY//STEROID RESPONSIVE MENINGITIS ARTERITIS//CNS IMMUNE RESPONSE