Class information for:
Level 1: DIPHTHERIA TOXIN//PSEUDOMONAS EXOTOXIN//IMMUNOTOXIN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
6550 1402 38.2 75%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1933 5231 RIBOSOME INACTIVATING PROTEINS//RICIN//TRICHOSANTHIN

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 DIPHTHERIA TOXIN Author keyword 45 33% 8% 113
2 PSEUDOMONAS EXOTOXIN Author keyword 16 43% 2% 29
3 IMMUNOTOXIN Author keyword 14 16% 6% 83
4 PSEUDOMONAS EXOTOXIN A Author keyword 13 38% 2% 27
5 RECOMBINANT IMMUNOTOXIN Author keyword 12 48% 1% 19
6 SECT MOL CANC THER EUT Address 11 57% 1% 13
7 FUSION TOXIN Author keyword 9 50% 1% 13
8 DAB389IL 2 Author keyword 8 75% 0% 6
9 BIOTHER Y SECT Address 8 62% 1% 8
10 SECT EXPT CANC IMMUNOL Address 6 71% 0% 5

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 DIPHTHERIA TOXIN 45 33% 8% 113 Search DIPHTHERIA+TOXIN Search DIPHTHERIA+TOXIN
2 PSEUDOMONAS EXOTOXIN 16 43% 2% 29 Search PSEUDOMONAS+EXOTOXIN Search PSEUDOMONAS+EXOTOXIN
3 IMMUNOTOXIN 14 16% 6% 83 Search IMMUNOTOXIN Search IMMUNOTOXIN
4 PSEUDOMONAS EXOTOXIN A 13 38% 2% 27 Search PSEUDOMONAS+EXOTOXIN+A Search PSEUDOMONAS+EXOTOXIN+A
5 RECOMBINANT IMMUNOTOXIN 12 48% 1% 19 Search RECOMBINANT+IMMUNOTOXIN Search RECOMBINANT+IMMUNOTOXIN
6 FUSION TOXIN 9 50% 1% 13 Search FUSION+TOXIN Search FUSION+TOXIN
7 DAB389IL 2 8 75% 0% 6 Search DAB389IL+2 Search DAB389IL+2
8 ANTIBODY REFOLDING 6 100% 0% 4 Search ANTIBODY+REFOLDING Search ANTIBODY+REFOLDING
9 B3 ANTIBODY 6 100% 0% 4 Search B3+ANTIBODY Search B3+ANTIBODY
10 PE38 5 63% 0% 5 Search PE38 Search PE38

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PSEUDOMONAS EXOTOXIN 49 25% 12% 170
2 SINGLE CHAIN IMMUNOTOXIN 36 58% 3% 42
3 DIPHTHERIA TOXIN 35 16% 14% 202
4 GENETIC CONSTRUCTION 30 64% 2% 29
5 RECOMBINANT IMMUNOTOXIN 30 35% 5% 69
6 BINDING DOMAIN SUBSTITUTION 24 82% 1% 14
7 A FRAGMENT 21 57% 2% 25
8 T DOMAIN 20 52% 2% 28
9 FRAGMENT A 20 52% 2% 27
10 RFB4DSFV PE38 BL22 19 74% 1% 14

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Immunotoxin treatment of cancer 2007 166 91 43%
Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century 2001 144 74 74%
Recombinant Immunotoxins Containing Truncated Bacterial Toxins for the Treatment of Hematologic Malignancies 2009 57 147 61%
Mechanism of Diphtheria Toxin Catalytic Domain Delivery to the Eukaryotic Cell Cytosol and the Cellular Factors that Directly Participate in the Process 2011 32 55 69%
Immunotoxins for leukemia 2014 12 72 43%
Penetration of protein toxins into cells 2000 172 54 54%
Therapeutic potential of anticancer immunotoxins 2011 30 62 55%
Immunotoxins for targeted cancer therapy 2006 121 264 45%
Immunotoxins: The Role of the Toxin 2013 15 98 34%
Treatment of Hematologic Malignancies with Immunotoxins and Antibody-Drug Conjugates 2011 39 53 43%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 SECT MOL CANC THER EUT 11 57% 0.9% 13
2 BIOTHER Y SECT 8 62% 0.6% 8
3 SECT EXPT CANC IMMUNOL 6 71% 0.4% 5
4 SECT BIOPHYS CHEM 6 53% 0.6% 8
5 PHARMACEUT PROD DEV 5 25% 1.2% 17
6 EXPT MED IMMUNOTHER Y 4 25% 1.1% 15
7 STEM CELL MOL BIOL 2 27% 0.6% 8
8 CLIN IMMUNOTHER Y SECT 2 36% 0.4% 5
9 DCBDC 2 67% 0.1% 2
10 US DOE STRUCT BIOL MOLEC MED 2 67% 0.1% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000144205 ELONGATION FACTOR 2 KINASE//EUKARYOTIC ELONGATION FACTOR 2 EEF2//ELONGATION FACTOR 2
2 0.0000139298 RIBOSOME INACTIVATING PROTEINS//TRICHOSANTHIN//RICIN
3 0.0000072341 ANTIBODY DRUG CONJUGATE//ANTIBODY DRUG CONJUGATES//T DM1
4 0.0000072070 ADP RIBOSYLTRANSFERASE//ADP RIBOSYLATION//CLOSTRIDIUM BOTULINUM C2 TOXIN
5 0.0000065531 LEUKEMIA STEM CELLS//EXPT THER EUT TRANSLAT ONCOL PROGRAM//LEUKEMIC STEM CELL
6 0.0000056876 CSE1L//PHOSPHO CSE1L//CELLULAR APOPTOSIS SUSCEPTIBILITY
7 0.0000056717 EXOU//EXOENZYME S//PSEUDOMONAL ELASTASE
8 0.0000054676 SCFV//SINGLE CHAIN FV//PHAGE DISPLAY
9 0.0000047100 INTERLEUKIN 2 RECEPTOR//IL 2 RECEPTOR//IL 2 RECEPTOR GAMMA CHAIN
10 0.0000041663 HB EGF//HEPARIN BINDING EGF LIKE GROWTH FACTOR//HEPARIN BINDING EPIDERMAL GROWTH FACTOR LIKE GROWTH FACTOR