Class information for:
Level 1: X LINKED AGAMMAGLOBULINEMIA//BRUTONS TYROSINE KINASE//BTK

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
8407 1187 46.5 88%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
313 17635 X LINKED AGAMMAGLOBULINEMIA//BRUTONS TYROSINE KINASE//BTK

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 X LINKED AGAMMAGLOBULINEMIA Author keyword 113 67% 9% 101
2 BRUTONS TYROSINE KINASE Author keyword 113 71% 8% 90
3 BTK Author keyword 84 56% 9% 101
4 XLA Author keyword 34 65% 3% 33
5 BTK GENE Author keyword 31 92% 1% 12
6 BRUTONS TYROSINE KINASE BTK Author keyword 21 71% 1% 17
7 TEC KINASE Author keyword 19 76% 1% 13
8 TEC KINASES Author keyword 15 82% 1% 9
9 ITK Author keyword 14 34% 3% 33
10 BRUTON TYROSINE KINASE Author keyword 14 65% 1% 13

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 X LINKED AGAMMAGLOBULINEMIA 113 67% 9% 101 Search X+LINKED+AGAMMAGLOBULINEMIA Search X+LINKED+AGAMMAGLOBULINEMIA
2 BRUTONS TYROSINE KINASE 113 71% 8% 90 Search BRUTONS+TYROSINE+KINASE Search BRUTONS+TYROSINE+KINASE
3 BTK 84 56% 9% 101 Search BTK Search BTK
4 XLA 34 65% 3% 33 Search XLA Search XLA
5 BTK GENE 31 92% 1% 12 Search BTK+GENE Search BTK+GENE
6 BRUTONS TYROSINE KINASE BTK 21 71% 1% 17 Search BRUTONS+TYROSINE+KINASE+BTK Search BRUTONS+TYROSINE+KINASE+BTK
7 TEC KINASE 19 76% 1% 13 Search TEC+KINASE Search TEC+KINASE
8 TEC KINASES 15 82% 1% 9 Search TEC+KINASES Search TEC+KINASES
9 ITK 14 34% 3% 33 Search ITK Search ITK
10 BRUTON TYROSINE KINASE 14 65% 1% 13 Search BRUTON+TYROSINE+KINASE Search BRUTON+TYROSINE+KINASE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 X LINKED AGAMMAGLOBULINEMIA 233 43% 35% 414
2 BTK 138 63% 12% 138
3 BRUTONS TYROSINE KINASE 102 31% 23% 278
4 BTK GENE 94 97% 2% 28
5 TEC FAMILY 79 71% 5% 64
6 DEFICIENT EXPRESSION 73 88% 3% 35
7 PCI 32765 56 68% 4% 49
8 TEC FAMILY KINASES 52 58% 5% 61
9 XLA 50 86% 2% 25
10 ITK 28 51% 3% 39

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species 2001 141 90 84%
Targeting Bruton's tyrosine kinase in B cell malignancies 2014 24 155 53%
Tec family kinases in T lymphocyte development and function 2005 160 206 67%
Primary B Cell Immunodeficiencies: Comparisons and Contrasts 2009 157 143 36%
Bruton Tyrosine Kinase (BTK) and Its Role in B-cell Malignancy 2012 52 111 53%
Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling 2005 111 101 71%
Ibrutinib and novel BTK inhibitors in clinical development 2013 26 62 71%
New insights into the regulation and functions of Tec family tyrosine kinases in the immune system 2002 59 65 77%
Targets for Ibrutinib Beyond B Cell Malignancies 2015 1 96 71%
Signaling network of the Btk family kinases 2000 105 107 72%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 IMMUNOL INFECT DIS PROGRAM 3 30% 0.8% 9
2 MOL IMMUNOL INFECT DIS 2 12% 1.6% 19
3 CHEM GENOM STRUCT BIOL 2 67% 0.2% 2
4 IMMUNOBIOL OPT INTEGRATED BIOSCI PROGRAM 1 100% 0.2% 2
5 WILLAMETTE VALLEY CANC 1 50% 0.2% 2
6 IMMUNOPHYSIOL SECT 1 33% 0.3% 3
7 JIANGSU MOL TARGETED ANTITUMOR DRUG 1 22% 0.3% 4
8 CLIN IMMUNOL MICROBIOL PATHOL INFECT DIS 1 33% 0.2% 2
9 PEDIAT IMMUNOL CLIN 1 33% 0.2% 2
10 PARKER HUGHES CANC 1 12% 0.5% 6

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000130816 SYK//SPLEEN TYROSINE KINASE//R788
2 0.0000116417 SLP 76//LINKER FOR ACTIVATION OF T CELLS//SECT LYMPHOCYTE SIGNALING
3 0.0000113903 COMMON VARIABLE IMMUNODEFICIENCY//IGA DEFICIENCY//CVID
4 0.0000110641 RECEPTOR EDITING//SURROGATE LIGHT CHAIN//PRE B CELL RECEPTOR
5 0.0000068945 OMENN SYNDROME//SEVERE COMBINED IMMUNODEFICIENCY//T CELL LYMPHOPENIA
6 0.0000060085 VAV//VAV1//VAV3
7 0.0000057894 SHIP2//INOSITOL 5 PHOSPHATASE//SHIP1
8 0.0000056414 ARID3B//JUMONJI//AT RICH INTERACTION DOMAIN
9 0.0000054304 PHOSPHOLIPASE C DELTA 1//PHOSPHOLIPASE C GAMMA 1//GENOME BIOSIGNAL
10 0.0000054178 TOFACITINIB//JAK3//CP 690 550