Class information for:
Level 1: TACE INHIBITORS//TACE INHIBITOR//MMP INHIBITORS

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
9359 1094 38.8 82%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
705 12205 MATRIX METALLOPROTEINASES//CD147//MATRIX METALLOPROTEINASE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 TACE INHIBITORS Author keyword 68 100% 2% 22
2 TACE INHIBITOR Author keyword 29 88% 1% 14
3 MMP INHIBITORS Author keyword 14 41% 2% 27
4 MMP 2 INHIBITORS Author keyword 14 100% 1% 7
5 GELATINASE INHIBITOR Author keyword 12 86% 1% 6
6 47J Address 9 83% 0% 5
7 MATRIX METALLOPROTEINASE INHIBITORS Author keyword 7 29% 2% 21
8 CANC AREA Address 7 67% 1% 6
9 ZINC BINDING GROUPS Author keyword 7 67% 1% 6
10 HYDROXAMATE Author keyword 6 21% 3% 28

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 TACE INHIBITORS 68 100% 2% 22 Search TACE+INHIBITORS Search TACE+INHIBITORS
2 TACE INHIBITOR 29 88% 1% 14 Search TACE+INHIBITOR Search TACE+INHIBITOR
3 MMP INHIBITORS 14 41% 2% 27 Search MMP+INHIBITORS Search MMP+INHIBITORS
4 MMP 2 INHIBITORS 14 100% 1% 7 Search MMP+2+INHIBITORS Search MMP+2+INHIBITORS
5 GELATINASE INHIBITOR 12 86% 1% 6 Search GELATINASE+INHIBITOR Search GELATINASE+INHIBITOR
6 MATRIX METALLOPROTEINASE INHIBITORS 7 29% 2% 21 Search MATRIX+METALLOPROTEINASE+INHIBITORS Search MATRIX+METALLOPROTEINASE+INHIBITORS
7 ZINC BINDING GROUPS 7 67% 1% 6 Search ZINC+BINDING+GROUPS Search ZINC+BINDING+GROUPS
8 HYDROXAMATE 6 21% 3% 28 Search HYDROXAMATE Search HYDROXAMATE
9 MMP SELECTIVITY 6 100% 0% 4 Search MMP+SELECTIVITY Search MMP+SELECTIVITY
10 MATRIX METALLOPROTEINASE INHIBITOR 5 21% 2% 22 Search MATRIX+METALLOPROTEINASE+INHIBITOR Search MATRIX+METALLOPROTEINASE+INHIBITOR

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MATRIX METALLOPROTEINASE INHIBITORS 79 30% 21% 225
2 MMP INHIBITORS 57 70% 4% 47
3 HYDROXAMATE INHIBITOR 51 83% 3% 29
4 CYCLIC SUCCINATE SERIES 38 93% 1% 14
5 STROMELYSIN INHIBITOR 31 92% 1% 12
6 ZINC BINDING GROUPS 30 60% 3% 33
7 THERAPEUTIC APPLICATION 28 51% 4% 40
8 TACE INHIBITORS 25 66% 2% 23
9 NON HYDROXAMATE INHIBITORS 24 91% 1% 10
10 HYDROXAMIC ACID INHIBITOR 18 83% 1% 10

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Design and therapeutic application of matrix metalloproteinase inhibitors 1999 674 286 43%
Current perspective of TACE inhibitors: A review 2009 54 107 68%
Novel methods and strategies in the discovery of TACE inhibitors 2013 7 70 84%
Recent developments in the design of specific matrix metalloproteinase inhibitors aided by structural and computational studies 2005 136 130 78%
New Hope for the Treatment of Osteoarthritis Through Selective Inhibition of MMP-13 2011 27 133 64%
To bind zinc or not to bind zinc: An examination of innovative approaches to improved metalloproteinase inhibition 2010 54 139 67%
Matrix metalloproteinases (MMPs): Chemical-biological functions and (Q)SARs 2007 146 139 50%
Towards third generation matrix metalloproteinase inhibitors for cancer therapy 2006 181 31 45%
The design, structure, and clinical update of small molecular weight matrix metalloproteinase inhibitors 2004 129 160 61%
Matrix metalloproteinase inhibitors: a patent review (2011-2013) 2014 4 74 50%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 47J 9 83% 0.5% 5
2 CANC AREA 7 67% 0.5% 6
3 HOKKAIDO ABORAT 6 100% 0.4% 4
4 ABT BIOCHEM 1 4 41% 0.6% 7
5 INFLAMMAT ONCOL 3 100% 0.3% 3
6 BIOL CALORIMETRY 2 67% 0.2% 2
7 MED TISSUE PHYSIOL CHIYODA KU 2 67% 0.2% 2
8 PROTEASES CANC PROGRAM 2 33% 0.5% 5
9 CORE BIOTECHNOL 2 43% 0.3% 3
10 530 CHOKEIJI 1 50% 0.2% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000225231 TUMOR TISSUE PROGRESSION//FIBROBLAST COLLAGENASE//CARRAGEENAN GRANULOMA
2 0.0000140832 MT1 MMP//CANC CELL//MMP 2
3 0.0000086517 ADAM//ADAM8//ADAM17
4 0.0000082474 AGGRECANASE//ADAMTS//ADAMTS 5
5 0.0000079866 SB 3CT//HEAD SHAKE RESPONSE//BBB BREAKDOWN
6 0.0000079297 CLOSTRIDIUM HISTOLYTICUM//FALGPA//PZ PEPTIDASE
7 0.0000055968 CHEM TECHNOL DRUGS//2 MERCAPTOBENZENESULFONAMIDE//2 MERCAPTOBENZENESULFONAMIDES
8 0.0000055584 TIMP 1//SORSBYS FUNDUS DYSTROPHY//SORSBY FUNDUS DYSTROPHY
9 0.0000051951 CARBOXYPEPTIDASE T//PROCARBOXYPEPTIDASE A//CALDECRIN
10 0.0000051287 AMINOHYDROXAMIC ACIDS//DIHYDROXAMIC ACIDS//DESFERRIOXAMINE B