Class information for:
Level 1: LRRK2//LEUCINE RICH REPEAT KINASE 2//PARK8

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
9586 1074 42.9 93%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
619 13202 ALPHA SYNUCLEIN//PARKIN//LRRK2

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 LRRK2 Author keyword 460 77% 29% 310
2 LEUCINE RICH REPEAT KINASE 2 Author keyword 111 86% 5% 56
3 PARK8 Author keyword 93 91% 4% 39
4 LEUCINE RICH REPEAT KINASE 2 LRRK2 Author keyword 85 85% 4% 45
5 G2019S Author keyword 46 82% 3% 27
6 DARDARIN Author keyword 34 79% 2% 22
7 G2019S MUTATION Author keyword 27 92% 1% 11
8 LRRK2 GENE Author keyword 21 85% 1% 11
9 CELL BIOL GENE EXP S UNIT Address 12 52% 2% 17
10 LRRK1 Author keyword 12 86% 1% 6

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 LRRK2 460 77% 29% 310 Search LRRK2 Search LRRK2
2 LEUCINE RICH REPEAT KINASE 2 111 86% 5% 56 Search LEUCINE+RICH+REPEAT+KINASE+2 Search LEUCINE+RICH+REPEAT+KINASE+2
3 PARK8 93 91% 4% 39 Search PARK8 Search PARK8
4 LEUCINE RICH REPEAT KINASE 2 LRRK2 85 85% 4% 45 Search LEUCINE+RICH+REPEAT+KINASE+2+LRRK2 Search LEUCINE+RICH+REPEAT+KINASE+2+LRRK2
5 G2019S 46 82% 3% 27 Search G2019S Search G2019S
6 DARDARIN 34 79% 2% 22 Search DARDARIN Search DARDARIN
7 G2019S MUTATION 27 92% 1% 11 Search G2019S+MUTATION Search G2019S+MUTATION
8 LRRK2 GENE 21 85% 1% 11 Search LRRK2+GENE Search LRRK2+GENE
9 LRRK1 12 86% 1% 6 Search LRRK1 Search LRRK1
10 EIF4G1 11 69% 1% 9 Search EIF4G1 Search EIF4G1

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 NEURONAL TOXICITY 330 96% 9% 101
2 LEUCINE RICH REPEAT KINASE 2 LRRK2 210 97% 6% 61
3 ROC DOMAIN 167 100% 4% 44
4 AUTOSOMAL DOMINANT PARKINSONISM 155 53% 19% 204
5 LEUCINE RICH REPEAT KINASE 2 149 98% 4% 40
6 G2019S 139 79% 8% 88
7 REPEAT KINASE 2 129 78% 8% 85
8 DISEASE ASSOCIATED MUTATIONS 124 71% 9% 101
9 G2019S MUTATION 115 83% 6% 66
10 GENE LRRK2 106 100% 3% 31

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
The Genetics of Parkinson's Disease: Progress and Therapeutic Implications 2013 75 78 42%
LRRK2 and neuroinflammation: partners in crime in Parkinson's disease? 2014 14 115 57%
LRRK2 and Parkinson Disease 2010 58 64 88%
Mechanisms of LRRK2-Mediated Neurodegeneration 2012 21 86 95%
Parkinson's disease: from monogenic forms to genetic susceptibility factors 2009 273 149 38%
Is inhibition of kinase activity the only therapeutic strategy for LRRK2-associated Parkinson's disease? 2012 21 70 90%
Progress in unraveling the genetic etiology of Parkinson disease in a genomic era 2015 4 118 26%
A visual review of the interactome of LRRK2: Using deep-curated molecular interaction data to represent biology 2015 2 72 46%
Small Molecule Kinase Inhibitors for LRRK2 and Their Application to Parkinson's Disease Models 2012 22 74 84%
Leucine-rich repeat kinase 2 (LRRK2) as a potential therapeutic target in Parkinson's disease 2012 25 79 77%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CELL BIOL GENE EXP S UNIT 12 52% 1.6% 17
2 WANGJIANG HOSP 7 56% 0.8% 9
3 RD CELL DESIGN 6 80% 0.4% 4
4 REGENERAT MED CELL DESIGN 6 80% 0.4% 4
5 BOOTH GARDNER PARKINSONS CARE 6 44% 1.0% 11
6 NEUROBIOL GENE THER Y 5 22% 2.0% 22
7 NEUROREGENERAT PROGRAM 5 27% 1.4% 15
8 PL NEUROGENET 4 42% 0.7% 8
9 CELL BIOL GENE EXP S SECT 4 38% 0.7% 8
10 TRANSGEN SECT 4 41% 0.7% 7

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000290955 PARKIN//PINK1//AUTOSOMAL RECESSIVE JUVENILE PARKINSONISM
2 0.0000130047 ALPHA SYNUCLEIN//SYNUCLEIN//BETA SYNUCLEIN
3 0.0000116810 CUERPO NEUROQUIM//NEUROREGENERAT GRP//TEAM ANIM OURCES
4 0.0000095809 RETROMER//SORTING NEXIN//VPS35
5 0.0000084470 MOL CELLULAR TOXICOL HUMAN PLICAT//OULU CITY HOSP//DOOR TO DOOR SURVEYS
6 0.0000076459 DJ 1//PARK7//DJ 1 PARK7
7 0.0000060173 PKAN//HALLERVORDEN SPATZ SYNDROME//NBIA
8 0.0000058252 NEUROPHARMACOL SECT//NEUROANAT EXPT NEUROL//PHARMACOL CHEM
9 0.0000046439 TRANSCRANIAL SONOGRAPHY//SUBSTANTIA NIGRA HYPERECHOGENICITY//BRAIN PARENCHYMA SONOGRAPHY
10 0.0000039546 PARKINSONS DISEASE DEMENTIA//MOTOR SUBTYPE//SECT PARKINSON DIS MOVEMENT DISORDERS