Class information for:
Level 1: GEMCITABINE//TROXACITABINE//DEOXYCYTIDINE KINASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
9691 1064 35.4 82%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1233 8561 DEOXYCYTIDINE KINASE//PURINE NUCLEOSIDE PHOSPHORYLASE//NUCLEOSIDE TRANSPORT

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 GEMCITABINE Author keyword 61 12% 43% 459
2 TROXACITABINE Author keyword 33 83% 2% 19
3 DEOXYCYTIDINE KINASE Author keyword 19 30% 5% 53
4 CYTIDINE DEAMINASE Author keyword 11 22% 4% 44
5 GEMZAR Author keyword 9 83% 0% 5
6 DEOXYCYTIDINE DEAMINASE Author keyword 8 70% 1% 7
7 SQUALENOYLATION Author keyword 8 70% 1% 7
8 FIXED DOSE RATE Author keyword 7 44% 1% 12
9 DFDU Author keyword 7 67% 1% 6
10 CLIN PHARMACOL ANALYT SERV Address 6 80% 0% 4

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 GEMCITABINE 61 12% 43% 459 Search GEMCITABINE Search GEMCITABINE
2 TROXACITABINE 33 83% 2% 19 Search TROXACITABINE Search TROXACITABINE
3 DEOXYCYTIDINE KINASE 19 30% 5% 53 Search DEOXYCYTIDINE+KINASE Search DEOXYCYTIDINE+KINASE
4 CYTIDINE DEAMINASE 11 22% 4% 44 Search CYTIDINE+DEAMINASE Search CYTIDINE+DEAMINASE
5 GEMZAR 9 83% 0% 5 Search GEMZAR Search GEMZAR
6 DEOXYCYTIDINE DEAMINASE 8 70% 1% 7 Search DEOXYCYTIDINE+DEAMINASE Search DEOXYCYTIDINE+DEAMINASE
7 SQUALENOYLATION 8 70% 1% 7 Search SQUALENOYLATION Search SQUALENOYLATION
8 FIXED DOSE RATE 7 44% 1% 12 Search FIXED+DOSE+RATE Search FIXED+DOSE+RATE
9 DFDU 7 67% 1% 6 Search DFDU Search DFDU
10 DFDCTP 6 80% 0% 4 Search DFDCTP Search DFDCTP

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 2 2 DIFLUORODEOXYCYTIDINE GEMCITABINE 144 76% 9% 100
2 2 2 DIFLUORODEOXYCYTIDINE 117 52% 15% 160
3 SELF POTENTIATION 60 83% 3% 34
4 2 2 DIFLUORO 2 DEOXYCYTIDINE 59 62% 6% 61
5 L CONFIGURATION 38 89% 2% 17
6 ANTICANCER AGENT GEMCITABINE 30 100% 1% 12
7 BCH 4556 27 92% 1% 11
8 DEOXYCYTIDINE KINASE 24 22% 9% 97
9 L DIOXOLANE CYTIDINE 23 70% 2% 19
10 DCK GENE 21 85% 1% 11

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Clinical pharmacology and pharmacogenetics of gemcitabine 2009 52 66 56%
Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases 2013 65 155 18%
Pharmacogenomics of gemcitabine: can genetic studies lead to tailor-made therapy? 2007 58 32 56%
Determinants of resistance to 2 ',2 '-difluorodeoxycytidine (gemcitabine) 2002 159 134 42%
Gemcitabine versus Modified Gemcitabine: A Review of Several Promising Chemical Modifications 2013 17 110 40%
Gemcitabine - A review of its pharmacology and clinical potential in non-small cell lung cancer and pancreatic cancer 1997 150 70 53%
CLINICAL AND PRECLINICAL ACTIVITY OF 2',2'-DIFLUORODEOXYCYTIDINE (GEMCITABINE) 1993 117 12 100%
Combined modality therapy of gemcitabine and radiation 2005 63 112 48%
Molecular Targets of Gemcitabine Action: Rationale for Development of Novel Drugs and Drug Combinations 2012 11 218 56%
Overcoming nucleoside analog chemoresistance of pancreatic cancer: A therapeutic challenge 2012 28 121 28%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ.
in class
1 CLIN PHARMACOL ANALYT SERV 6 80% 0.4% 4
2 UMR 8612IFR 141 5 63% 0.5% 5
3 LA TIMONE UNIV HOSP MARSEILLE 3 100% 0.3% 3
4 TRANSFER ONCOL 3 100% 0.3% 3
5 LCOPM 3 60% 0.3% 3
6 UMR BIOCIS 8076 3 26% 0.8% 9
7 CANC PHARMACOL THER EUT GRP 2 67% 0.2% 2
8 PHARMIFR ITFM 141 2 67% 0.2% 2
9 CLIN PHARMACOL NEW DRUG DEV UNIT 2 50% 0.3% 3
10 CANC CLIN ONCOL 2 16% 0.8% 9

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000205253 CLOFARABINE//CANC THER EUT IMMUNOL//NELARABINE
2 0.0000140063 NUCLEOSIDE TRANSPORT//NITROBENZYLTHIOINOSINE//NUCLEOSIDE TRANSPORTER
3 0.0000139028 CYTIDINE DEAMINASE//ANTIBIOTIC FUNGICIDE//BLASTICIDIN S DEAMINASE
4 0.0000135424 URACIL ARABINOSIDE//ARA CTP//CYTOSINE ARABINOSIDE
5 0.0000126800 ADVANCED PANCREATIC CANCER//FOLFIRINOX//METASTATIC PANCREATIC CANCER
6 0.0000118397 ERCC1//RRM1//MED OVARIAN CANC SECT
7 0.0000110660 POLG//MNGIE//DEOXYRIBONUCLEOSIDE KINASE
8 0.0000095613 VINORELBINE//GEMCITABINE//ADVANCED NON SMALL CELL LUNG CANCER
9 0.0000074261 CYCLOPENTENYL CYTOSINE//CTP SYNTHASE//CTP SYNTHETASE
10 0.0000060767 METASTATIC BREAST CANCER//VINORELBINE//DOCETAXEL