Class information for:
Level 1: 19 OXYGENATION//HUMAN PLACENTAL MICROSOME//HUMAN PLACENTAL MICROSOMES

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
9722 1062 31.9 60%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1561 6752 STEROIDS//OSW 1//SQUALAMINE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 19 OXYGENATION Author keyword 17 100% 1% 8
2 HUMAN PLACENTAL MICROSOME Author keyword 12 86% 1% 6
3 HUMAN PLACENTAL MICROSOMES Author keyword 9 67% 1% 8
4 SUICIDE SUBSTRATE Author keyword 8 34% 2% 20
5 STEROIDAL INHIBITORS Author keyword 6 80% 0% 4
6 16 ALPHA HYDROXYANDROSTENEDIONE Author keyword 6 100% 0% 4
7 17 ALPHA HYDROXYLASE 17 20 LYASE CYP17 INHIBITORS Author keyword 6 100% 0% 4
8 TIME DEPENDENT INACTIVATION Author keyword 4 50% 1% 6
9 ESTUDOS FARMACEUT Address 3 16% 2% 20
10 17 ALPHA HYDROXYLASE C 17 C 20 LYASE Author keyword 3 100% 0% 3

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 19 OXYGENATION 17 100% 1% 8 Search 19+OXYGENATION Search 19+OXYGENATION
2 HUMAN PLACENTAL MICROSOME 12 86% 1% 6 Search HUMAN+PLACENTAL+MICROSOME Search HUMAN+PLACENTAL+MICROSOME
3 HUMAN PLACENTAL MICROSOMES 9 67% 1% 8 Search HUMAN+PLACENTAL+MICROSOMES Search HUMAN+PLACENTAL+MICROSOMES
4 SUICIDE SUBSTRATE 8 34% 2% 20 Search SUICIDE+SUBSTRATE Search SUICIDE+SUBSTRATE
5 STEROIDAL INHIBITORS 6 80% 0% 4 Search STEROIDAL+INHIBITORS Search STEROIDAL+INHIBITORS
6 16 ALPHA HYDROXYANDROSTENEDIONE 6 100% 0% 4 Search 16+ALPHA+HYDROXYANDROSTENEDIONE Search 16+ALPHA+HYDROXYANDROSTENEDIONE
7 17 ALPHA HYDROXYLASE 17 20 LYASE CYP17 INHIBITORS 6 100% 0% 4 Search 17+ALPHA+HYDROXYLASE+17+20+LYASE+CYP17+INHIBITORS Search 17+ALPHA+HYDROXYLASE+17+20+LYASE+CYP17+INHIBITORS
8 TIME DEPENDENT INACTIVATION 4 50% 1% 6 Search TIME+DEPENDENT+INACTIVATION Search TIME+DEPENDENT+INACTIVATION
9 17 ALPHA HYDROXYLASE C 17 C 20 LYASE 3 100% 0% 3 Search 17+ALPHA+HYDROXYLASE+C+17+C+20+LYASE Search 17+ALPHA+HYDROXYLASE+C+17+C+20+LYASE
10 17 ALPHA HYDROXYLASE C17 3 100% 0% 3 Search 17+ALPHA+HYDROXYLASE+C17 Search 17+ALPHA+HYDROXYLASE+C17

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 HUMAN PLACENTAL AROMATASE 150 70% 12% 126
2 ESTROGEN BIOSYNTHESIS 39 26% 12% 131
3 P45017 ALPHA 39 68% 3% 34
4 P450 17 35 81% 2% 21
5 STRUCTURALLY MODIFIED DERIVATIVES 32 85% 2% 17
6 HUMAN 17 ALPHA HYDROXYLASE 17 20 LYASE CYP17 29 77% 2% 20
7 4 ANDROSTENE 3 6 17 TRIONE 23 86% 1% 12
8 4 HYDROXY 4 ANDROSTENE 3 17 DIONE 21 85% 1% 11
9 TETRAHYDRONAPHTHALENES 18 89% 1% 8
10 P450 AROM 17 100% 1% 8

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Aromatase inhibitors in the treatment of breast cancer 2005 214 133 37%
Nonsteroidal aromatase inhibitors: Recent advances 2002 63 105 55%
Inhibition of CYP 17, a new strategy for the treatment of prostate cancer 2002 41 56 71%
A review of mechanistic studies on aromatase (CYP19) and 17 alpha-hydroxylase-17,20-lyase (CYP17) 2011 19 61 38%
Computational methods for the design of potent aromatase inhibitors 2013 6 91 43%
Inhibitors of 17 alpha-hydroxylase/17,20-lyase (CYP17): Potential agents for the treatment of prostate cancer 1999 66 99 36%
CYP17 inhibitors for prostate cancer treatment - An update 2008 25 216 38%
Inhibitors of steroidal cytochrome P450 enzymes as targets for drug development 2007 28 62 50%
Current status on development of steroids as anticancer agents 2013 19 146 16%
Human aromatase: Perspectives in biochemistry and biotechnology 2013 4 65 45%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ESTUDOS FARMACEUT 3 16% 1.9% 20
2 HRICHTUNG PHARMAZEUT MED CHEM 12 1 3 60% 0.3% 3
3 CNRSEP 9 2 67% 0.2% 2
4 UP EA BIOMOL THER IES ANTITUMORALES 4021 2 67% 0.2% 2
5 PHARMACEUT CHEM GRP 1 38% 0.3% 3
6 DRUG DISCOVERY MED CHEM 3 1 100% 0.2% 2
7 HORMONES CANC PROGRAM 1 100% 0.2% 2
8 ENDOCRINE BIOCHEM 1 21% 0.5% 5
9 ADV STUDY PHARMACEUT SCI 1 50% 0.1% 1
10 FR PHARMACEUT MED CHEM 8 5 1 50% 0.1% 1

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000199634 STEROID SULFATASE//ESTRONE SULFATASE//AROMATASE
2 0.0000159571 D HOMOSTEROIDS//FUSED STEROIDS//16 17 SECOSTEROIDS
3 0.0000140667 ESTROGENIC RECRUITMENT//AMINOGLUTETHIMIDE//CYCLIC TREATMENT
4 0.0000128381 AROMATASE INHIBITORS//EXEMESTANE//ANASTROZOLE
5 0.0000120222 WESTPHALEN REARRANGEMENT//IMIDE REDUCTION//FOSSIL BIOMARKERS
6 0.0000117442 17 ALPHA HYDROXYLASE 17 20 LYASE DEFICIENCY//17 ALPHA HYDROXYLASE DEFICIENCY//ADRENARCHE
7 0.0000090233 HOMO AZA STEROIDAL ESTERS//STEROIDAL ESTERS//HOMO AZA STEROIDS
8 0.0000079160 CYTOCHROME P450 INTERACTIONS//NONLINEAR CLEARANCE//NONLINEAR LIVER BINDING
9 0.0000066870 17 BETA HYDROXYSTEROID DEHYDROGENASE//17 BETA HSD2//17 BETA HSD1
10 0.0000062344 5 ALPHA REDUCTASE//FINASTERIDE//BIOL SYST ANIM PROD