Class information for:
Level 2: ALDOSE REDUCTASE//ALDO KETO REDUCTASE//17 BETA HYDROXYSTEROID DEHYDROGENASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
1801 5753 35.2 69%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
54 89702 MENOPAUSE//POLYCYSTIC OVARY SYNDROME//ESTROGEN

Classes in level below (level 1)


ID, lev. below Publications Label for level below
2911 2038 ALDOSE REDUCTASE//AKR1B10//ALDOSE REDUCTASE INHIBITOR
7380 1294 STEROID SULFATASE//ESTRONE SULFATASE//AROMATASE
9789 1055 DIHYDRODIOL DEHYDROGENASE//CARBONYL REDUCTASE//ALDO KETO REDUCTASE
11515 909 17 BETA HYDROXYSTEROID DEHYDROGENASE//17 BETA HSD2//17 BETA HSD1
19056 457 X LINKED ICHTHYOSIS//STEROID SULFATASE DEFICIENCY//STS GENE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ALDOSE REDUCTASE Author keyword 339 57% 7% 400
2 ALDO KETO REDUCTASE Author keyword 181 65% 3% 172
3 17 BETA HYDROXYSTEROID DEHYDROGENASE Author keyword 97 54% 2% 124
4 STEROID SULFATASE Author keyword 95 65% 2% 90
5 AKR1B10 Author keyword 88 89% 1% 40
6 X LINKED ICHTHYOSIS Author keyword 79 88% 1% 37
7 ALDOSE REDUCTASE INHIBITOR Author keyword 71 49% 2% 105
8 ALDOSE REDUCTASE INHIBITORS Author keyword 65 63% 1% 65
9 POLYOL PATHWAY Author keyword 57 46% 2% 92
10 ESTRONE SULFATASE Author keyword 55 87% 0% 27

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 ALDOSE REDUCTASE 339 57% 7% 400 Search ALDOSE+REDUCTASE Search ALDOSE+REDUCTASE
2 ALDO KETO REDUCTASE 181 65% 3% 172 Search ALDO+KETO+REDUCTASE Search ALDO+KETO+REDUCTASE
3 17 BETA HYDROXYSTEROID DEHYDROGENASE 97 54% 2% 124 Search 17+BETA+HYDROXYSTEROID+DEHYDROGENASE Search 17+BETA+HYDROXYSTEROID+DEHYDROGENASE
4 STEROID SULFATASE 95 65% 2% 90 Search STEROID+SULFATASE Search STEROID+SULFATASE
5 AKR1B10 88 89% 1% 40 Search AKR1B10 Search AKR1B10
6 X LINKED ICHTHYOSIS 79 88% 1% 37 Search X+LINKED+ICHTHYOSIS Search X+LINKED+ICHTHYOSIS
7 ALDOSE REDUCTASE INHIBITOR 71 49% 2% 105 Search ALDOSE+REDUCTASE+INHIBITOR Search ALDOSE+REDUCTASE+INHIBITOR
8 ALDOSE REDUCTASE INHIBITORS 65 63% 1% 65 Search ALDOSE+REDUCTASE+INHIBITORS Search ALDOSE+REDUCTASE+INHIBITORS
9 POLYOL PATHWAY 57 46% 2% 92 Search POLYOL+PATHWAY Search POLYOL+PATHWAY
10 ESTRONE SULFATASE 55 87% 0% 27 Search ESTRONE+SULFATASE Search ESTRONE+SULFATASE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ALDEHYDE REDUCTASE 173 54% 4% 225
2 ESTRONE SULFATASE 138 72% 2% 109
3 DIABETIC COMPLICATIONS 112 28% 6% 341
4 ESTROGEN DEPENDENT DISEASES 103 97% 1% 30
5 KETO REDUCTASE SUPERFAMILY 91 62% 2% 95
6 17 BETA HYDROXYSTEROID DEHYDROGENASE 87 48% 2% 132
7 SORBINIL 84 58% 2% 98
8 DIHYDRODIOL DEHYDROGENASE 83 51% 2% 117
9 3 ALPHA HYDROXYSTEROID DEHYDROGENASE 80 48% 2% 123
10 KETO REDUCTASES 79 94% 1% 29

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Advance in Dietary Polyphenols as Aldose Reductases Inhibitors: Structure-Activity Relationship Aspect 2015 4 85 38%
Relationships of sex steroid hormone levels in benign and cancerous breast tissue and blood: A critical appraisal of current science 2015 2 27 52%
Transcriptional control of local estrogen formation by aromatase in the breast 2015 2 135 46%
Aldo-keto reductases and bioactivation/detoxication 2007 165 114 56%
Steroid sulfatase: Molecular biology, regulation, and inhibition 2005 239 255 64%
THE ALDO-KETO REDUCTASE SUPERFAMILY AND ITS ROLE IN DRUG METABOLISM AND DETOXIFICATION 2008 131 298 60%
17 beta-Hydroxysteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) family; nomenclature and main characteristics of the 17HSD/KSR enzymes 1999 180 75 85%
Aldose reductase, oxidative stress, and diabetic mellitus 2012 34 98 55%
Aldose reductase in glucose toxicity: A potential target for the prevention of diabetic complications 1998 286 103 58%
Aromatase, breast cancer and obesity: a complex interaction 2012 33 73 56%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 OCULAR THER EUT 40 79% 0.5% 26
2 STERIX LTD 27 51% 0.7% 38
3 ONCOL MOL ENDOCRINOL 18 23% 1.2% 70
4 EXCELLENCE ENVIRONM TOXICOL 14 27% 0.7% 43
5 CECIL H IDA GREEN REPROD BIOL SCI 9 18% 0.7% 43
6 IGBMCUPR BIOL STRUCT 8 100% 0.1% 5
7 ENDOCRINOL GENOM UNIT 7 57% 0.1% 8
8 GRP MOL ENDOCRINOL 7 34% 0.3% 16
9 TOXICOL PHARMACOL NAT SCIENTISTS 6 27% 0.3% 20
10 ABORATING REPROD HLTH 6 35% 0.2% 13

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000019396 DIABETIC NEUROPATHY//SYMPATHETIC SKIN RESPONSE//NERVE BLOOD FLOW
2 0.0000012464 2 METHOXYESTRADIOL//INDOLE 3 CARBINOL//3 3 DIINDOLYLMETHANE
3 0.0000012047 STEROIDS//OSW 1//SQUALAMINE
4 0.0000010456 OLEOYL ESTRONE//APOLIPOPROTEIN D//BREAST CYST FLUID
5 0.0000009467 ALPHA CRYSTALLIN//CATARACT//LENS
6 0.0000008991 TAMOXIFEN//AROMATASE INHIBITORS//ANASTROZOLE
7 0.0000008132 CONGENITAL ADRENAL HYPERPLASIA//21 HYDROXYLASE DEFICIENCY//CYP21A2
8 0.0000007733 ADVANCED GLYCATION END PRODUCTS//HMGB1//RAGE
9 0.0000007380 MAMMOGRAPHIC DENSITY//BREAST DENSITY//CANCER CAUSES & CONTROL
10 0.0000007201 SULFOTRANSFERASE//RENALASE//PHENOL SULFOTRANSFERASE