Class information for:
Level 2: 11 BETA HYDROXYSTEROID DEHYDROGENASE//ALDOSTERONE//EPLERENONE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
1985 5079 40.6 82%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
252 41951 PHEOCHROMOCYTOMA//NEUROBLASTOMA//ALDOSTERONE

Classes in level below (level 1)


ID, lev. below Publications Label for level below
2008 2324 ALDOSTERONE//EPLERENONE//SPIRONOLACTONE
2137 2275 11 BETA HYDROXYSTEROID DEHYDROGENASE//11 BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1//11 BETA HSD1
18558 480 HIGH BLOOD P SURE UNIT//ADRENOCORTICOTROPHIC HORMONE//GLUCOCORTICOID INDUCED HYPERTENSION

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 11 BETA HYDROXYSTEROID DEHYDROGENASE Author keyword 470 74% 7% 344
2 ALDOSTERONE Author keyword 283 26% 19% 941
3 EPLERENONE Author keyword 184 67% 3% 164
4 11 BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1 Author keyword 183 84% 2% 98
5 MINERALOCORTICOID RECEPTOR Author keyword 150 39% 6% 304
6 SPIRONOLACTONE Author keyword 121 36% 5% 274
7 11 BETA HSD1 Author keyword 119 75% 2% 85
8 MOL HYPERTENS Address 63 81% 1% 38
9 HIGH BLOOD P SURE UNIT Address 47 88% 0% 22
10 11 BETA HSD2 Author keyword 42 62% 1% 43

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 11 BETA HYDROXYSTEROID DEHYDROGENASE 470 74% 7% 344 Search 11+BETA+HYDROXYSTEROID+DEHYDROGENASE Search 11+BETA+HYDROXYSTEROID+DEHYDROGENASE
2 ALDOSTERONE 283 26% 19% 941 Search ALDOSTERONE Search ALDOSTERONE
3 EPLERENONE 184 67% 3% 164 Search EPLERENONE Search EPLERENONE
4 11 BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1 183 84% 2% 98 Search 11+BETA+HYDROXYSTEROID+DEHYDROGENASE+TYPE+1 Search 11+BETA+HYDROXYSTEROID+DEHYDROGENASE+TYPE+1
5 MINERALOCORTICOID RECEPTOR 150 39% 6% 304 Search MINERALOCORTICOID+RECEPTOR Search MINERALOCORTICOID+RECEPTOR
6 SPIRONOLACTONE 121 36% 5% 274 Search SPIRONOLACTONE Search SPIRONOLACTONE
7 11 BETA HSD1 119 75% 2% 85 Search 11+BETA+HSD1 Search 11+BETA+HSD1
8 11 BETA HSD2 42 62% 1% 43 Search 11+BETA+HSD2 Search 11+BETA+HSD2
9 GLUCOCORTICOID METABOLISM 40 77% 1% 27 Search GLUCOCORTICOID+METABOLISM Search GLUCOCORTICOID+METABOLISM
10 MINERALOCORTICOID 33 32% 2% 87 Search MINERALOCORTICOID Search MINERALOCORTICOID

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 APPARENT MINERALOCORTICOID EXCESS 410 69% 7% 354
2 CORTICOSTEROID 11 BETA DEHYDROGENASE 349 91% 3% 144
3 EPLERENONE 239 64% 5% 236
4 SPIRONOLACTONE 219 37% 9% 470
5 11 BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1 188 41% 7% 353
6 CORTISOL METABOLISM 185 73% 3% 143
7 HEXOSE 6 PHOSPHATE DEHYDROGENASE 160 75% 2% 115
8 MINERALOCORTICOID RECEPTOR 159 34% 8% 390
9 BETA HYDROXYSTEROID DEHYDROGENASE 154 54% 4% 199
10 11 BETA HYDROXYSTEROID DEHYDROGENASE 153 33% 8% 383

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Role of Mineralocorticoid Receptor Antagonists in Cardiovascular Disease 2015 4 84 74%
11 beta-HYDROXYSTEROID DEHYDROGENASES: INTRACELLULAR GATE-KEEPERS OF TISSUE GLUCOCORTICOID ACTION 2013 47 735 67%
11 beta-hydroxysteroid dehydrogenase type 1: A tissue-specific regulator of glucocorticoid response 2004 518 358 77%
Mineralocorticoid Receptor Activation and Mineralocorticoid Receptor Antagonist Treatment in Cardiac and Renal Diseases 2015 2 103 83%
Mineralocorticoid receptors in the heart: lessons from cell-selective transgenic animals 2015 2 85 73%
Aldosterone: effects on the kidney and cardiovascular system 2010 98 137 79%
Vascular Actions of Aldosterone 2013 23 83 88%
Narrative Review: The Emerging Clinical Implications of the Role of Aldosterone in the Metabolic Syndrome and Resistant Hypertension 2009 150 45 64%
11beta-Hydroxysteroid dehydrogenase type 1 inhibitors: novel agents for the treatment of metabolic syndrome and obesity-related disorders? 2013 24 103 75%
Aldosterone synthase inhibitors in cardiovascular and renal diseases 2014 9 38 82%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MOL HYPERTENS 63 81% 0.7% 38
2 HIGH BLOOD P SURE UNIT 47 88% 0.4% 22
3 MOL SYST TOXICOL 21 48% 0.6% 32
4 U478 9 25% 0.6% 31
5 MED CHEM CLIN PHARM 7 50% 0.2% 10
6 REG ENDOCRINE UNIT 7 41% 0.3% 13
7 DEV ENDOCRINE SIGNALLING 4 42% 0.2% 8
8 JULIUS BERNSTEIN PHYSIOL 4 18% 0.4% 21
9 QUEEN ELIZABETH HOSP MED 4 56% 0.1% 5
10 ASSAY DEV SCREENING 3 39% 0.1% 7

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000019543 GLUCOCORTICOID RECEPTOR//GLUCOCORTICOID RESISTANCE//TRANSREPRESSION
2 0.0000015920 GLYCYRRHIZIN//LICORICE//GLABRIDIN
3 0.0000013110 TORASEMIDE//HYPERKALEMIA//FUROSEMIDE
4 0.0000011561 KCC2//ENAC//EPITHELIAL SODIUM CHANNEL
5 0.0000011226 CONGENITAL ADRENAL HYPERPLASIA//21 HYDROXYLASE DEFICIENCY//CYP21A2
6 0.0000010111 DOPING CONTROL//EPITESTOSTERONE//DOPING ANALYSIS
7 0.0000009988 GITELMANS SYNDROME//GITELMAN SYNDROME//BARTTER SYNDROME
8 0.0000009714 CORTISOL AWAKENING RESPONSE//SALIVARY CORTISOL//HAIR CORTISOL
9 0.0000009479 ANGIOTENSIN II//ANGIOTENSIN 1 7//RENIN ANGIOTENSIN SYSTEM
10 0.0000009303 PHEOCHROMOCYTOMA//NEUROBLASTOMA//PRIMARY ALDOSTERONISM