Class information for:
Level 2: JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS//NONMEM

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
1987 5071 29.6 56%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
316 35223 P GLYCOPROTEIN//MULTIDRUG RESISTANCE//SGLT2 INHIBITOR

Classes in level below (level 1)


ID, lev. below Publications Label for level below
5645 1528 JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS//NONMEM//INDIRECT RESPONSE MODELS
9503 1082 INTERSPECIES SCALING//DMPK TRANSLAT SCI//WELL STIRRED MODEL
12239 857 BOF 4272//MULTIPLE INDICATOR DILUTION//HEPATIC ELIMINATION
14872 675 ASAN FDN//DA 125//MED DIAGNOST PATHOL
16012 611 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//DISTRIBUTION CLEARANCE//CURVE MOMENTS
26555 206 INO 2628 CZ//DOUBLE PEAKS//DISCONTINUOUS ABSORPTION
32124 112 ORAL PHARMACOL THER EUT//PHARMACEUT SCI BIOPHARMACEUT MIZUHO KU//31 TANABE DORIMIZUHO KU

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS Journal 171 42% 6% 311
2 JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS Journal 160 48% 5% 248
3 NONMEM Author keyword 57 29% 3% 168
4 INDIRECT RESPONSE MODELS Author keyword 40 82% 0% 23
5 PL PHARMACOKINET Address 34 36% 1% 76
6 ASAN FDN Address 33 83% 0% 19
7 BIOPHARMACEUTICS & DRUG DISPOSITION Journal 26 11% 4% 212
8 DA 125 Author keyword 23 86% 0% 12
9 PHARMACOKINET DRUG THER Y Address 23 33% 1% 58
10 INTERSPECIES SCALING Author keyword 22 53% 1% 30

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 NONMEM 57 29% 3% 168 Search NONMEM Search NONMEM
2 INDIRECT RESPONSE MODELS 40 82% 0% 23 Search INDIRECT+RESPONSE+MODELS Search INDIRECT+RESPONSE+MODELS
3 DA 125 23 86% 0% 12 Search DA+125 Search DA+125
4 INTERSPECIES SCALING 22 53% 1% 30 Search INTERSPECIES+SCALING Search INTERSPECIES+SCALING
5 PHARMACOMETRICS 22 42% 1% 40 Search PHARMACOMETRICS Search PHARMACOMETRICS
6 WELL STIRRED MODEL 19 74% 0% 14 Search WELL+STIRRED+MODEL Search WELL+STIRRED+MODEL
7 DA 8159 19 64% 0% 18 Search DA+8159 Search DA+8159
8 BOF 4272 18 89% 0% 8 Search BOF+4272 Search BOF+4272
9 MODEL BASED DRUG DEVELOPMENT 17 63% 0% 17 Search MODEL+BASED+DRUG+DEVELOPMENT Search MODEL+BASED+DRUG+DEVELOPMENT
10 POPULATION PHARMACOKINETICS 16 12% 2% 120 Search POPULATION+PHARMACOKINETICS Search POPULATION+PHARMACOKINETICS

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 DOSAGE REGIMENS 94 51% 3% 130
2 PLASMA PARTITION COEFFICIENTS 64 72% 1% 50
3 INTRINSIC CLEARANCE 62 45% 2% 104
4 MULTIPLE INDICATOR DILUTION 55 70% 1% 45
5 HUMAN DRUG CLEARANCE 52 80% 1% 32
6 HEPATIC METABOLIC CLEARANCE 47 81% 1% 29
7 NONMEM 44 38% 2% 91
8 INDIRECT PHARMACODYNAMIC RESPONSES 42 78% 1% 28
9 LOCAL DISPOSITION 41 90% 0% 18
10 HEPATIC ELIMINATION 37 61% 1% 40

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS 171 42% 6% 311
2 JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 160 48% 5% 248
3 BIOPHARMACEUTICS & DRUG DISPOSITION 26 11% 4% 212

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Combining the 'bottom up' and 'top down' approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data 2015 6 55 44%
A novel strategy for physiologically based predictions of human pharmacokinetics 2006 155 60 78%
Physiologically-Based Pharmacokinetics in Drug Development and Regulatory Science 2011 161 164 29%
Prediction of Human Pharmacokinetics From Preclinical Information: Comparative Accuracy of Quantitative Prediction Approaches 2009 102 44 59%
The application of allometric scaling principles to predict pharmacokinetic parameters across species 2014 5 42 79%
The Simcyp (R) Population-based ADME Simulator 2009 123 36 47%
Pharmacokinetics 2014 15 124 24%
Prediction of Human Pharmacokinetics from Preclinical Information of Rhein, an Antidiabetic Nephropathy Drug, Using a Physiologically Based Pharmacokinetic Model 2014 5 22 55%
Model-based clinical drug development in the past, present and future: a commentary 2015 1 28 64%
Simulation of clinical trials 2000 119 30 63%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PL PHARMACOKINET 34 36% 1.5% 76
2 ASAN FDN 33 83% 0.4% 19
3 PHARMACOKINET DRUG THER Y 23 33% 1.1% 58
4 PHARMACEUT EVALUAT 1 21 75% 0.3% 15
5 MED DIAGNOST PATHOL 21 90% 0.2% 9
6 WOODMONT OFF 2 21 85% 0.2% 11
7 SECT PHARMACOKINET 18 44% 0.6% 31
8 ASAN FDNASAN MED 18 89% 0.2% 8
9 DMPK TRANSLAT SCI 15 88% 0.1% 7
10 OFF CLIN PHARMACOL BIOPHARMACEUT 14 39% 0.6% 28

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000018204 APA HAMSTER//APA HAMSTERS//AMINO ACID LOAD
2 0.0000016274 PEPT1//PEPT2//HPEPT1
3 0.0000011884 CYTOCHROME P450//CYP2D6//PREGNANE X RECEPTOR
4 0.0000011699 RAPID EQUILIBRIUM//UNSTABLE PRODUCT//ELECT ENGN ELECT AUTOMAT COMMUN
5 0.0000009055 TORASEMIDE//HYPERKALEMIA//FUROSEMIDE
6 0.0000008834 REGUCALCIN//SMP30//ENDOCRINOL MOL METAB
7 0.0000008824 BIOANALYSIS//LC NMR//DRIED BLOOD SPOT DBS
8 0.0000008587 CAFFEINE//COFFEE//ENERGY DRINKS
9 0.0000006993 CHEMOTHERAPY-TOKYO//JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY//CEFEPIME
10 0.0000006714 VISNAGIN//AMMI VISNAGA//FURANOCHROMONES