Class information for: |
Basic class information |
| ID | Publications | Average number of references |
Avg. shr. active ref. in WoS |
|---|---|---|---|
| 2158 | 4521 | 52.1 | 94% |
Classes in level above (level 3) |
| ID, lev. above |
Publications | Label for level above |
|---|---|---|
| 402 | 27207 | RESVERATROL//C ELEGANS//CAENORHABDITIS ELEGANS |
Classes in level below (level 1) |
| ID, lev. below | Publications | Label for level below |
|---|---|---|
| 1510 | 2532 | SIRT1//SIRTUIN//SIRT3 |
| 9852 | 1050 | FOXO//FOXO3A//FOXO1 |
| 11132 | 939 | FOXM1//FORKHEAD BOX M1//WINGED HELIX DNA BINDING DOMAIN |
Terms with highest relevance score |
| Rank | Term | Type of term | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
|---|---|---|---|---|---|---|
| 1 | SIRT1 | Author keyword | 325 | 48% | 11% | 503 |
| 2 | SIRTUIN | Author keyword | 183 | 61% | 4% | 194 |
| 3 | FOXM1 | Author keyword | 177 | 73% | 3% | 136 |
| 4 | SIRT3 | Author keyword | 157 | 79% | 2% | 101 |
| 5 | SIRTUINS | Author keyword | 156 | 53% | 5% | 210 |
| 6 | SIRT2 | Author keyword | 106 | 81% | 1% | 64 |
| 7 | SIRT5 | Author keyword | 65 | 95% | 0% | 21 |
| 8 | SIRT6 | Author keyword | 47 | 69% | 1% | 40 |
| 9 | FOXO3A | Author keyword | 45 | 38% | 2% | 94 |
| 10 | FOXO | Author keyword | 43 | 33% | 2% | 106 |
Web of Science journal categories |
Author Key Words |
| Rank | Web of Science journal category | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
LCSH search | Wikipedia search |
|---|---|---|---|---|---|---|---|
| 1 | SIRT1 | 325 | 48% | 11% | 503 | Search SIRT1 | Search SIRT1 |
| 2 | SIRTUIN | 183 | 61% | 4% | 194 | Search SIRTUIN | Search SIRTUIN |
| 3 | FOXM1 | 177 | 73% | 3% | 136 | Search FOXM1 | Search FOXM1 |
| 4 | SIRT3 | 157 | 79% | 2% | 101 | Search SIRT3 | Search SIRT3 |
| 5 | SIRTUINS | 156 | 53% | 5% | 210 | Search SIRTUINS | Search SIRTUINS |
| 6 | SIRT2 | 106 | 81% | 1% | 64 | Search SIRT2 | Search SIRT2 |
| 7 | SIRT5 | 65 | 95% | 0% | 21 | Search SIRT5 | Search SIRT5 |
| 8 | SIRT6 | 47 | 69% | 1% | 40 | Search SIRT6 | Search SIRT6 |
| 9 | FOXO3A | 45 | 38% | 2% | 94 | Search FOXO3A | Search FOXO3A |
| 10 | FOXO | 43 | 33% | 2% | 106 | Search FOXO | Search FOXO |
Key Words Plus |
| Rank | Web of Science journal category | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
|---|---|---|---|---|---|
| 1 | CALORIE RESTRICTION | 287 | 34% | 16% | 703 |
| 2 | SIRTUINS | 266 | 61% | 6% | 284 |
| 3 | FACTOR FKHR | 168 | 71% | 3% | 137 |
| 4 | DEACETYLASE | 165 | 39% | 7% | 336 |
| 5 | SIR2 LIKE PROTEINS | 161 | 77% | 2% | 111 |
| 6 | PROTEIN DEACETYLASES | 150 | 71% | 3% | 120 |
| 7 | DEPENDENT DEACETYLASE | 150 | 83% | 2% | 84 |
| 8 | FORKHEAD TRANSCRIPTION FACTORS | 117 | 26% | 9% | 394 |
| 9 | SMALL MOLECULE ACTIVATORS | 110 | 51% | 3% | 153 |
| 10 | TRANSCRIPTION FACTOR FOXM1 | 103 | 85% | 1% | 55 |
Journals |
Reviews |
| Title | Publ. year | Cit. | Active references | % act. ref. to same field |
|---|---|---|---|---|
| Sirtuins as regulators of metabolism and healthspan | 2012 | 293 | 152 | 71% |
| SIRT1 and other sirtuins in metabolism | 2014 | 52 | 114 | 74% |
| Small molecule SIRT1 activators for the treatment of aging and age-related diseases | 2014 | 48 | 98 | 58% |
| Recent progress in the biology and physiology of sirtuins | 2009 | 490 | 82 | 80% |
| Small-Molecule Allosteric Activators of Sirtuins | 2014 | 36 | 118 | 69% |
| Mammalian Sirtuins: Biological Insights and Disease Relevance | 2010 | 548 | 276 | 62% |
| Sirtuin modulators: an updated patent review (2012-2014) | 2015 | 2 | 25 | 96% |
| The growing landscape of lysine acetylation links metabolism and cell signalling | 2014 | 53 | 156 | 37% |
| Sorting out functions of sirtuins in cancer | 2014 | 24 | 202 | 67% |
| Sirtuins, Aging, and Medicine | 2011 | 158 | 82 | 83% |
Address terms |
| Rank | Address term | Relevance score (tfidf) |
Class's shr. of term's tot. occurrences |
Shr. of publ. in class containing term |
Num. of publ. in class |
|---|---|---|---|---|---|
| 1 | PAUL F GLENN | 25 | 77% | 0.4% | 17 |
| 2 | PAUL F GLENN S BIOL MECH AGING | 16 | 48% | 0.6% | 25 |
| 3 | SIRTRIS | 9 | 83% | 0.1% | 5 |
| 4 | GLENN S BIOL MECH AGING | 7 | 64% | 0.2% | 7 |
| 5 | GLENN SCI AGING | 7 | 64% | 0.2% | 7 |
| 6 | COMM CELLULAR MOL PHYSIOL | 6 | 53% | 0.2% | 8 |
| 7 | CELL SENESCENCE | 6 | 33% | 0.3% | 15 |
| 8 | GLENN S AGING | 4 | 75% | 0.1% | 3 |
| 9 | INTEGRAT SYST PHYSIOL LISP NCEM | 4 | 75% | 0.1% | 3 |
| 10 | YORKSHIRE CANC UNIT P53 | 4 | 75% | 0.1% | 3 |
Related classes at same level (level 2) |
| Rank | Relatedness score | Related classes |
|---|---|---|
| 1 | 0.0000031244 | RESVERATROL//TRANS RESVERATROL//PTEROSTILBENE |
| 2 | 0.0000021958 | TRANSHYDROGENASE//WLDS//NAD KINASE |
| 3 | 0.0000017809 | IRISIN//FGF 21//FIBROBLAST GROWTH FACTOR 21 |
| 4 | 0.0000011808 | C ELEGANS//CAENORHABDITIS ELEGANS//DAF 16 |
| 5 | 0.0000011699 | PROTEIN KINASE D//PROTEIN KINASE D PKD//MEF2C |
| 6 | 0.0000011137 | LONGEVITY//HORMESIS//CALORIC RESTRICTION |
| 7 | 0.0000010897 | MODY//MATURITY ONSET DIABETES OF THE YOUNG//NEONATAL DIABETES |
| 8 | 0.0000009995 | FATTY ACID SYNTHASE//AMPK//AMP ACTIVATED PROTEIN KINASE |
| 9 | 0.0000009748 | EPITHELIAL MESENCHYMAL TRANSITION//EMT//SNAIL |
| 10 | 0.0000008994 | PTEN//MTOR//LHERMITTE DUCLOS DISEASE |