Class information for:
Level 2: DUOCARMYCINS//PYRROLOBENZODIAZEPINE//PYRROLE IMIDAZOLE POLYAMIDE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
2357 3920 34.5 71%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
333 33297 HUMAN SERUM ALBUMIN//CARDIOTOXICITY//BOVINE SERUM ALBUMIN

Classes in level below (level 1)


ID, lev. below Publications Label for level below
3216 1959 PYRROLE IMIDAZOLE POLYAMIDE//DISTAMYCIN//MINOR GROOVE BINDERS
14862 676 PENTAMIDINE//DIAMIDINES//AROMATIC DIAMIDINES
15070 664 PYRROLOBENZODIAZEPINE//PYRROLOBENZODIAZEPINES//PYRROLO2 1 C1 4BENZODIAZEPINES
15823 621 DUOCARMYCINS//CC 1065//DUOCARMYCIN

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 DUOCARMYCINS Author keyword 87 94% 1% 31
2 PYRROLOBENZODIAZEPINE Author keyword 83 90% 1% 36
3 PYRROLE IMIDAZOLE POLYAMIDE Author keyword 79 94% 1% 29
4 PYRROLOBENZODIAZEPINES Author keyword 79 94% 1% 29
5 MINOR GROOVE BINDERS Author keyword 68 80% 1% 43
6 CC 1065 Author keyword 67 89% 1% 31
7 DISTAMYCIN Author keyword 57 65% 1% 55
8 DUOCARMYCIN Author keyword 48 77% 1% 33
9 ADOZELESIN Author keyword 45 94% 0% 16
10 PYRROLO2 1 C1 4BENZODIAZEPINES Author keyword 45 94% 0% 16

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 DUOCARMYCINS 87 94% 1% 31 Search DUOCARMYCINS Search DUOCARMYCINS
2 PYRROLOBENZODIAZEPINE 83 90% 1% 36 Search PYRROLOBENZODIAZEPINE Search PYRROLOBENZODIAZEPINE
3 PYRROLE IMIDAZOLE POLYAMIDE 79 94% 1% 29 Search PYRROLE+IMIDAZOLE+POLYAMIDE Search PYRROLE+IMIDAZOLE+POLYAMIDE
4 PYRROLOBENZODIAZEPINES 79 94% 1% 29 Search PYRROLOBENZODIAZEPINES Search PYRROLOBENZODIAZEPINES
5 MINOR GROOVE BINDERS 68 80% 1% 43 Search MINOR+GROOVE+BINDERS Search MINOR+GROOVE+BINDERS
6 CC 1065 67 89% 1% 31 Search CC+1065 Search CC+1065
7 DISTAMYCIN 57 65% 1% 55 Search DISTAMYCIN Search DISTAMYCIN
8 DUOCARMYCIN 48 77% 1% 33 Search DUOCARMYCIN Search DUOCARMYCIN
9 ADOZELESIN 45 94% 0% 16 Search ADOZELESIN Search ADOZELESIN
10 PYRROLO2 1 C1 4BENZODIAZEPINES 45 94% 0% 16 Search PYRROLO2+1+C1+4BENZODIAZEPINES Search PYRROLO2+1+C1+4BENZODIAZEPINES

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ENHANCED FUNCTIONAL ANALOGS 292 100% 2% 69
2 CC 1065 292 77% 5% 196
3 NETROPSIN 287 67% 7% 261
4 DISTAMYCIN 283 61% 8% 305
5 LEXITROPSINS 212 95% 2% 72
6 PYRROLE IMIDAZOLE POLYAMIDES 209 78% 3% 137
7 LEFT HAND SUBUNIT 204 90% 2% 89
8 NONCOVALENT BINDING SELECTIVITY 192 98% 1% 49
9 DISTAMYCIN A 182 71% 4% 148
10 DNA ALKYLATION PROPERTIES 157 100% 1% 42

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Recognition of the DNA minor groove by pyrrole-imidazole polyamides 2003 358 71 89%
Molecular recognition of DNA by small molecules 2001 594 84 71%
The mammalian molybdenum enzymes of mARC 2015 1 92 36%
DNA minor groove binders as potential antitumor and antimicrobial agents 2004 186 200 85%
DNA minor-groove recognition by small molecules 2001 268 231 82%
Synthesis of DNA-Interactive Pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) 2011 35 191 88%
Sequence-specific DNA recognition by polyamides 1999 217 41 88%
CC-1065 and the duocarmycins: Understanding their biological function through mechanistic studies 1996 222 184 92%
Minor groove binders as anti-infective agents 2013 15 59 73%
Synthesis and biological properties of sequence-specific DNA-alkylating pyrrole-imidazole polyamides 2006 60 49 92%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CANC UK GENE TARGETED DRUG DESIGN GRP 38 89% 0.4% 17
2 GENE TARGETED DRUG DESIGN GRP 32 85% 0.4% 17
3 SPIROGEN LTD 21 90% 0.2% 9
4 CANC UK DRUG DNA INTERACT GRP 20 49% 0.8% 30
5 GENE TARGETING DRUG DESIGN GRP 12 86% 0.2% 6
6 MED CHEM DRUG TECHNOL 10 44% 0.4% 17
7 CR UK DRUG DNA INTERACT GRP 8 70% 0.2% 7
8 CRC GENE TARGETED DRUG DESIGN GRP 8 100% 0.1% 5
9 DNA INTERACT GRP 6 80% 0.1% 4
10 YORKSHIRE CANC DRUG DESIGN 5 43% 0.2% 9

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000021375 Z DNA//JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS//B Z TRANSITION
2 0.0000016919 HAPLOID EMBRYONIC STEM CELLS//POLYACENAPHTHYLENE//FRAGMIN PROTAMINE MICROPARTICLES
3 0.0000016469 CARDIOTOXICITY//ANTHRACYCLINES//DOXORUBICIN
4 0.0000016257 RESONANCE RAYLEIGH SCATTERING//RESONANCE LIGHT SCATTERING//DNA BINDING
5 0.0000015669 MEYERS INTERDISCIPLINARY ORGAN MED CHE//BLEOMYCIN HYDROLASE//BLEOMYCIN AMPLIFICATION
6 0.0000015118 BENZIMIDAZOLE//BENZIMIDAZOLES//BENZOXAZOLES
7 0.0000012486 DT DIAPHORASE//EO9//NQO1
8 0.0000009452 PRODIGIOSIN//PYRROLES//LAMELLARIN
9 0.0000008894 ARYNES//ENEDIYNES//ENEDIYNE
10 0.0000008747 PNEUMOCYSTIS CARINII//PNEUMOCYSTIS JIROVECII//PNEUMOCYSTIS CARINII PNEUMONIA