Class information for:
Level 2: IVABRADINE//SINOATRIAL NODE//HCN CHANNELS

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
2641 3000 38.1 78%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
58 88565 PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY//ATRIAL FIBRILLATION//CARDIAC & CARDIOVASCULAR SYSTEM

Classes in level below (level 1)


ID, lev. below Publications Label for level below
3997 1791 SINOATRIAL NODE//HCN CHANNELS//PACEMAKER CURRENT
11123 940 IVABRADINE//RESTING HEART RATE//HOWARD GILMAN HEART VALVE DIS
24138 269 ZATEBRADINE//YM758//ALINIDINE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 IVABRADINE Author keyword 234 68% 7% 205
2 SINOATRIAL NODE Author keyword 116 43% 7% 208
3 HCN CHANNELS Author keyword 86 71% 2% 69
4 PACEMAKER CURRENT Author keyword 82 77% 2% 56
5 MOL PHYSIOL NEUROBIOL Address 65 95% 1% 21
6 HYPERPOLARIZATION ACTIVATED CURRENT Author keyword 61 70% 2% 50
7 HCN CHANNEL Author keyword 58 72% 2% 46
8 I H Author keyword 51 55% 2% 63
9 HCN4 Author keyword 50 76% 1% 35
10 I F CURRENT Author keyword 40 79% 1% 26

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 IVABRADINE 234 68% 7% 205 Search IVABRADINE Search IVABRADINE
2 SINOATRIAL NODE 116 43% 7% 208 Search SINOATRIAL+NODE Search SINOATRIAL+NODE
3 HCN CHANNELS 86 71% 2% 69 Search HCN+CHANNELS Search HCN+CHANNELS
4 PACEMAKER CURRENT 82 77% 2% 56 Search PACEMAKER+CURRENT Search PACEMAKER+CURRENT
5 HYPERPOLARIZATION ACTIVATED CURRENT 61 70% 2% 50 Search HYPERPOLARIZATION+ACTIVATED+CURRENT Search HYPERPOLARIZATION+ACTIVATED+CURRENT
6 HCN CHANNEL 58 72% 2% 46 Search HCN+CHANNEL Search HCN+CHANNEL
7 I H 51 55% 2% 63 Search I+H Search I+H
8 HCN4 50 76% 1% 35 Search HCN4 Search HCN4
9 I F CURRENT 40 79% 1% 26 Search I+F+CURRENT Search I+F+CURRENT
10 ZD7288 40 66% 1% 37 Search ZD7288 Search ZD7288

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PACEMAKER CHANNELS 324 70% 9% 267
2 CURRENT IF 203 81% 4% 124
3 RABBIT SINOATRIAL NODE 193 63% 7% 195
4 RATE REDUCTION 168 73% 4% 127
5 SINO ATRIAL NODE 156 73% 4% 120
6 BRADYCARDIAC AGENT 147 79% 3% 94
7 I F INHIBITOR 123 72% 3% 96
8 CALF PURKINJE FIBERS 110 78% 2% 72
9 HCN CHANNELS 107 65% 3% 103
10 FUNNY CURRENT 107 82% 2% 63

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
HCN Channels-Modulators of Cardiac and Neuronal Excitability 2015 3 101 91%
Hyperpolarization-Activated Cation Channels: From Genes to Function 2009 264 426 62%
Resting Heart Rate: Risk Indicator and Emerging Risk Factor in Cardiovascular Disease 2015 4 117 62%
The Role of the Funny Current in Pacemaker Activity 2010 137 105 86%
Neurophysiology of HCN channels: From cellular functions to multiple regulations 2014 24 241 59%
Hyperpolarization-activated cation currents: From molecules to physiological function 2003 586 137 72%
A Coupled SYSTEM of Intracellular Ca2+ Clocks and Surface Membrane Voltage Clocks Controls the Timekeeping Mechanism of the Heart's Pacemaker 2010 128 93 73%
Exploring HCN channels as novel drug targets 2011 49 137 91%
HCN channels: Structure, cellular regulation and physiological function 2009 126 235 57%
Genesis and regulation of the heart automaticity 2008 172 485 52%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MOL PHYSIOL NEUROBIOL 65 95% 0.7% 21
2 HOWARD GILMAN HEART VALVE DIS 19 64% 0.6% 18
3 ETTORE SANSAVINI HLTH SCI FDN 8 46% 0.4% 13
4 CIMMBA 7 43% 0.4% 13
5 FISIOL MOL NEUROBIOL 6 80% 0.1% 4
6 DAVEE NEUROL CLIN NEUROSCI 5 27% 0.5% 15
7 KLIN INNERE MED KARDIOL ANGIOL INTERNIST INTENSIV 4 75% 0.1% 3
8 PHARM PHARMAKOL NAT WISSEN 4 56% 0.2% 5
9 PATHOL CARDIAQUES VASC 3 50% 0.2% 5
10 LA PITIE SALPETRIERE HOSP 3 21% 0.5% 14

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000019072 LONG QT SYNDROME//BRUGADA SYNDROME//QT INTERVAL
2 0.0000013647 NEUROSCI REGENERAT//ERYTHROMELALGIA//NAV17
3 0.0000012279 HEART RATE VARIABILITY//RESPIRATORY SINUS ARRHYTHMIA//AUTONOMIC NERVOUS SYSTEM
4 0.0000011677 CONOTOXIN//MIBEFRADIL//CONOTOXINS
5 0.0000011557 SCORPION TOXINS//SCORPION VENOM//POTASSIUM CHANNEL
6 0.0000011120 CARDIOPLEGIA//JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY//CARIPORIDE
7 0.0000010189 CARVEDILOL//NEBIVOLOL//BETA BLOCKERS
8 0.0000009472 CATHETER ABLATION//ATRIOVENTRICULAR NODAL REENTRANT TACHYCARDIA//ATRIAL FLUTTER
9 0.0000008804 AMIODARONE//DESETHYLAMIODARONE//PROPAFENONE
10 0.0000008173 ATRIAL FIBRILLATION//PULMONARY VEIN ISOLATION//CATHETER ABLATION